Click here to switch to the map view.

The map label for this gene is aslB [H]

Identifier: 157163272

GI number: 157163272

Start: 4011371

End: 4012606

Strand: Direct

Name: aslB [H]

Synonym: EcHS_A4019

Alternate gene names: 157163272

Gene position: 4011371-4012606 (Clockwise)

Preceding gene: 157163271

Following gene: 157163279

Centisome position: 86.39

GC content: 52.27

Gene sequence:

>1236_bases
ATGCTGCAACAGGTTCCAACGCGTGCTTTTCATGTGATGGCGAAACCGAGTGGTTCCGATTGTAATCTGAACTGTGACTA
CTGTTTTTATCTCGAAAAACAATCCCTTTACCGCGAAAAGCCAGTCACGCATATGGACGATGACACGCTGGAAGCGTATA
TCCGTCACTATATCGCCGCCAGCGAACTGCAAAACGAAGTGGCTTTTACCTGGCAGGGCGGCGAACCAACGCTACTCGGG
CTGGAGTTTTACCGCCGTGCCGTAGCGCTACAGGCGAAATATGGTGCTGGCAGGAAGATAAGTAACAGCTTCCAGACTAA
CGGCGTGCTGCTGGATGACGAATGGTGCGCGTTTCTCGCGGAGCATCATTTTCTTGTTGGTTTATCGCTGGATGGTCCGC
CTGAGATCCACAATCAATATCGCGTGACTAAAGGTGGCAGACCCACGCATAAGCTGGTGATGCGTGCCCTGACGCTGCTG
CAAAAACATCATGTCGACTATAACGTGCTGGTCTGCGTTAATCGCACCAGCGCGCAGCAACCGTTGCAGGTATATGATTT
TTTGTGCGATGCGGGAGTGGAATTCATCCAGTTTATTCCGGTGGTCGAGCGCCTGGCTGATGAAACGGCTGCCCGCGAAG
GACTGAAATTGCATGCGCCTGGTGATATTCAGGGTGAGCTAACGGAATGGTCGGTGCGCCCCGAGGAGTTCGGTGAATTT
CTGGTGGCGATATTCGACCACTGGATCAAACGCGACGTCGGCAAGATTTTCGTGATGAATATCGAATGGGCGTTTGCCAA
TTTTGTCGGTGCGCCGGGTGCGGTTTGCCATCATCAGCCAACCTGTGGGCGCTCGGTGATTGTTGAGCACAACGGCGACG
TTTACGCCTGCGATCACTATGTTTATCCACAATATCGGCTGGGGAATATGCACCAGCAAACAATTGCAGAAATGATCGAT
TCCCCGCAACAGCAGGTGTTTGGTGAAGATAAATTTAAGCAATTACCGGCGCAGTGTCGCAGTTGTAACGTGTTAAAAGC
GTGCTGGGGAGGCTGCCCGAAACACCGCTTCATGCTCGATGCCAGCGGCAAACCGGGGCTGAATTATTTGTGTGCCGGGT
ATCAGCGTTATTTCCGCCATCTACCGCCATATCTTAAAGCAATGGCTGATTTGCTGGCGCACGGTCGCCCGGCCAGTGAC
ATTATGCATGCGCATTTGCTGGTGGTGAGTAAGTAA

Upstream 100 bases:

>100_bases
GTCACCCTCCCTTCGCAATAAACGCCCGTAATAACTCATTGCCCCACGGTATGATTTCGCCCTTAACGTATTGAAGGATG
ACTTCAGGCAAGGAGTGACC

Downstream 100 bases:

>100_bases
AAAAGCGGCCATTTTGTGGCCGCCTGCGGTTGATTGCCGGATGCGGCGTAAACGCCTTATCCGGCCTACATGATCGTGCA
AATTCAATAAATTGCAGCGT

Product: arylsulfatase-activating protein AslB

Products: NA

Alternate protein names: AnSME homolog [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYIRHYIAASELQNEVAFTWQGGEPTLLG
LEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAEHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAAREGLKLHAPGDIQGELTEWSVRPEEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMHAHLLVVSK

Sequences:

>Translated_411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYIRHYIAASELQNEVAFTWQGGEPTLLG
LEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAEHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAAREGLKLHAPGDIQGELTEWSVRPEEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMHAHLLVVSK
>Mature_411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYIRHYIAASELQNEVAFTWQGGEPTLLG
LEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAEHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAAREGLKLHAPGDIQGELTEWSVRPEEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMHAHLLVVSK

Specific function: Potential Positive Factor For The Regulation Of Arylsulfatase. [C]

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=411, Percent_Identity=98.5401459854015, Blast_Score=854, Evalue=0.0,
Organism=Escherichia coli, GI87081923, Length=392, Percent_Identity=41.0714285714286, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 46614; Mature: 46614

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYIRHYIAA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SELQNEVAFTWQGGEPTLLGLEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLA
HHHCCCEEEEEECCCCEEEHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEECHHHHHHHH
EHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSAQQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PLQVYDFLCDAGVEFIQFIPVVERLADETAAREGLKLHAPGDIQGELTEWSVRPEEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEECCCCHHHHHHH
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEECE
VYPQYRLGNMHQQTIAEMIDSPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
ECCCHHCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASDIMHAHLLVVSK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHEEEEEEEEC
>Mature Secondary Structure
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYIRHYIAA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SELQNEVAFTWQGGEPTLLGLEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLA
HHHCCCEEEEEECCCCEEEHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEECHHHHHHHH
EHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSAQQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PLQVYDFLCDAGVEFIQFIPVVERLADETAAREGLKLHAPGDIQGELTEWSVRPEEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEECCCCHHHHHHH
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEECE
VYPQYRLGNMHQQTIAEMIDSPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
ECCCHHCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASDIMHAHLLVVSK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 11222759 [H]