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The map label for this gene is hokA

Identifier: 157163032

GI number: 157163032

Start: 3749751

End: 3749903

Strand: Reverse

Name: hokA

Synonym: EcHS_A3758

Alternate gene names: 157163032

Gene position: 3749903-3749751 (Counterclockwise)

Preceding gene: 157163035

Following gene: 157163029

Centisome position: 80.76

GC content: 35.29

Gene sequence:

>153_bases
ATGCCGCAGAAATATAGATTACTTTCTTTAATAGTGATTTGTTTCACGCTTTTATTTTTCACCTGGATGATAAGAGATTC
ACTGTGTGAATTGCATATTAAACAGGAGAGTTATGAGCTGGCGGCGTTTTTAGCCTGCAAATTGAAAGAGTAA

Upstream 100 bases:

>100_bases
AGGGTATTTTGGCTTTGACATATTAGGGGCTATTCCATTTCATCGTCCAACAAAATGGGTGCAGTACATACTCGTTGGAA
ATCAACACAGGAGGCTGGGA

Downstream 100 bases:

>100_bases
GAGTCTTCGGCGGGAAATTATTCCCGCCTTACTTACGGCGTTGCGCATTCTCATTGCACCCAAATTTATTCTTCACAAAA
ATAATAATAGATTTTATTAC

Product: small toxic polypeptide

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 50; Mature: 49

Protein sequence:

>50_residues
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE

Sequences:

>Translated_50_residues
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE
>Mature_49_residues
PQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family

Homologues:

Organism=Escherichia coli, GI48994947, Length=50, Percent_Identity=100, Blast_Score=102, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HOKA_ECOLI (P37305)

Other databases:

- EMBL:   M30139
- EMBL:   U00039
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_004237.1
- RefSeq:   YP_026229.1
- ProteinModelPortal:   P37305
- STRING:   P37305
- EnsemblBacteria:   EBESCT00000004259
- EnsemblBacteria:   EBESCT00000014596
- GeneID:   2847732
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3526
- KEGG:   eco:b4455
- EchoBASE:   EB2250
- EcoGene:   EG12346
- GeneTree:   EBGT00050000009511
- HOGENOM:   HBG473224
- OMA:   TILLLTW
- ProtClustDB:   PRK09759
- BioCyc:   EcoCyc:MONOMER0-1605
- Genevestigator:   P37305
- InterPro:   IPR000021
- InterPro:   IPR018084
- PRINTS:   PR00281
- ProDom:   PD005979

Pfam domain/function: PF01848 HOK_GEF

EC number: NA

Molecular weight: Translated: 5998; Mature: 5867

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17dcd384)-;

Cys/Met content:

6.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
10.0 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
PQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2404279; 8041620; 9278503; 7940673; 7984428; 10361310