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The map label for this gene is yhjK

Identifier: 157163008

GI number: 157163008

Start: 3724942

End: 3726897

Strand: Reverse

Name: yhjK

Synonym: EcHS_A3732

Alternate gene names: 157163008

Gene position: 3726897-3724942 (Counterclockwise)

Preceding gene: 157163009

Following gene: 157163007

Centisome position: 80.26

GC content: 52.61

Gene sequence:

>1956_bases
ATGGCAATGGTGGCAGCCGTTGTCCTGGTGTTCGTTTTTATTTTTTGCACCGTTTTGCTGTTCCATCTGGTCCAGCAGAA
TCGCTATAACACGGCTACGCAACTGGAAAGCATTGCTCGCTCTGTCCGCGAACCCTTATCTTCAGCTATTTTGAAAGGCG
ATATTCCCGAAGCGGAAGCTATTCTTGCCAGCATTAAACCGGCAGGCGTGGTCAGCCGTGCCGATGTAGTGCTGCCTAAC
CAGTTCCAGGCGCTGCGTAAAAGTTTTATTCCAGAGCGCCCGGTGCCGGTAATGGTTACTCGCCTGTTTGAGCTACCGGT
TCAAATCTCGCTGGGCGTTTACTCGCTCGAACGTCCGGCAAACCCGCAGCCAATTGCCTATCTGGTACTACAGGCGGATT
CCTTCCGTATGTATAAGTTCGTGATGAGCACCCTCTCAACGTTAGTGACCATTTACTTACTTTTGTCGCTTATCCTGACC
GTCGCCATCAGCTGGTGCATTAACCGCCTGATTTTGCATCCGTTACGCAATATTGCTCGCGAACTTAACGCCATCCCAGC
CAAGGAGCTTGTTGGTCACCAACTGGCATTACCGCGTCTGCATCAGGACGATGAAATCGGTATGTTGGTGCGCAGTTACA
ACCTCAACCAGCAATTGCTGCAGCGCCATTATGAAGAACAGAACGAAAATGCGATGCGCTTCCCGGTGTCGGATTTGCCG
AACAAAGCCTTGCTGATGGAGATGCTGGAGCAGGTTGTCGCGCGTAAACAAACCACCGCGCTGATGATCATCACCTGTGA
AACCCTGCGTGATACTGCGGGCGTGCTGAAAGAGGCGCAACGAGAAATTCTGCTGCTGACGCTGGTGGAAAAACTCAAAT
CGGTACTGTCGCCACGTATGATCCTCGCGCAGATTAGCGGTTATGACTTTGCTGTCATTGCCAACGGTGTACAGGAACCG
TGGCACGCAATCACCTTAGGTCAGCAAGTGCTCACTATCATGAGCGAGCGCCTGCCGATTGAACGTATTCAACTCCGTCC
GCACTGTAGCATTGGCGTGGCGATGTTCTACGGCGATCTCACCGCCGAACAGCTTTACAGTCGCGCTATTTCTGCGGCAT
TTACCGCTCGCCATAAAGGCAAGAATCAGATTCAGTTCTTTGATCCGCAGCAGATGGAAGCCGCCCAGAAGCGGTTGACG
GAAGAGAGCGATATCCTTAATGCACTGGAAAATCATCAGTTTGCTATTTGGTTACAGCCACAGGTCGAGATGACCAGCGG
TAAACTGGTCAGTGCGGAAGTGTTACTGCGTATCCAGCAACCGGATGGCAGTTGGGACCTGCCGGATGGCTTAATCGATC
GCATTGAGTGCTGTGGGCTGATGGTTACCGTCGGTCACTGGGTGCTGGAAGAGTCCTGTCGATTGCTTGCAGCCTGGCAA
GAGCGCGGCATTATGCTGCCCTTGTCGGTAAACCTCTCTGCGCTGCAACTGATGCACCCGAATATGGTGGCGGATATGCT
GGAACTGTTAACCCGCTATCGCATTCAGCCGGGAACACTGATTCTGGAAGTGACAGAAAGCCGACGTATTGACGACCCTC
ATGCTGCGGTGGCAATCCTCCGTCCGCTGCGCAATGCCGGAGTTCGGGTGGCGCTGGATGATTTCGGCATGGGCTACGCA
GGGCTGCGTCAGCTGCAGCATATGAAATCGTTGCCAATCGACGTACTGAAAATCGACAAAATGTTTGTTGAAGGCTTGCC
GGGAGATAGCAGCATGATTGCTGCAATTATCATGCTGGCGCAGAGCCTGAACTTACAAATGATTGCCGAAGGCGTGGAGA
CTGAAGCACAACGCGACTGGCTGGCAAAAGCGGGCGTTGGTATTGCCCAGGGCTTCCTTTTTGCTCGCCCACTCCCTATT
GAAATCTTCGAAGAGAGTTACCTGGAAGAAAAGTAG

Upstream 100 bases:

>100_bases
CCTCTCTTAATGCCGCTGCGATCGGGTATACTCGGGCGGCAATCTGGGATTTCCGGGGGGAGACAATTTGCGCGTAAGTC
GCTCGTTAACAATCAAGCAG

Downstream 100 bases:

>100_bases
CTACCCCAAACTGATTACAAAACTTTAAAAAGTGCTGGTTTGTGCGAGCCAGCTCAAACTTTTTAACCTTTTTGTTTCAA
TTATGATCCAGGTACATTTC

Product: putative phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPN
QFQALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILT
VAISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLP
NKALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEP
WHAITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLT
EESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQ
ERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDFGMGYA
GLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPI
EIFEESYLEEK

Sequences:

>Translated_651_residues
MAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPN
QFQALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILT
VAISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLP
NKALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEP
WHAITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLT
EESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQ
ERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDFGMGYA
GLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPI
EIFEESYLEEK
>Mature_650_residues
AMVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQ
FQALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILTV
AISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPN
KALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPW
HAITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLTE
ESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQE
RGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDFGMGYAG
LRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPIE
IFEESYLEEK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain

Homologues:

Organism=Escherichia coli, GI226510982, Length=651, Percent_Identity=100, Blast_Score=1328, Evalue=0.0,
Organism=Escherichia coli, GI1787541, Length=428, Percent_Identity=31.7757009345794, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI87081921, Length=416, Percent_Identity=31.9711538461538, Blast_Score=188, Evalue=8e-49,
Organism=Escherichia coli, GI87081743, Length=237, Percent_Identity=35.4430379746835, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI1790496, Length=251, Percent_Identity=37.4501992031873, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1786507, Length=243, Percent_Identity=33.7448559670782, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=31.2, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87081980, Length=262, Percent_Identity=31.6793893129771, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788502, Length=253, Percent_Identity=31.2252964426877, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788849, Length=252, Percent_Identity=28.968253968254, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI87082096, Length=211, Percent_Identity=33.175355450237, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1787055, Length=267, Percent_Identity=26.2172284644195, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787410, Length=153, Percent_Identity=32.6797385620915, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHJK_ECOLI (P37649)

Other databases:

- EMBL:   U00039
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S47750
- RefSeq:   AP_004264.1
- RefSeq:   NP_417986.4
- ProteinModelPortal:   P37649
- DIP:   DIP-12384N
- IntAct:   P37649
- STRING:   P37649
- EnsemblBacteria:   EBESCT00000004631
- EnsemblBacteria:   EBESCT00000015249
- GeneID:   948048
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5943
- KEGG:   eco:b3529
- EchoBASE:   EB2165
- EcoGene:   EG12256
- eggNOG:   COG2200
- GeneTree:   EBGT00050000008777
- HOGENOM:   HBG751764
- ProtClustDB:   PRK13561
- BioCyc:   EcoCyc:EG12256-MONOMER
- Genevestigator:   P37649
- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003660
- SMART:   SM00052
- SMART:   SM00267
- TIGRFAMs:   TIGR00254

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00672 HAMP; SSF55073 A/G_cyclase

EC number: NA

Molecular weight: Translated: 73082; Mature: 72951

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50883 EAL; PS50887 GGDEF; PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x184dea08)-; HASH(0x17ab68ec)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEA
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ILASIKPAGVVSRADVVLPNQFQALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPA
HHHHCCCCCCCCCCCEECCHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECEEEECCCC
NPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILTVAISWCINRLILHPLRNIAR
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNAIPAKELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLP
HHHCCCHHHHHCCHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEECCHHHCC
NKALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRM
CHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ILAQISGYDFAVIANGVQEPWHAITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDL
HHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEHHHHHCCH
TAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQP
HHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECC
QVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQ
CEEECCCCEEEEEHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAIL
HCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHH
RPLRNAGVRVALDDFGMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLA
HHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK
HHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCH
>Mature Secondary Structure 
AMVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ILASIKPAGVVSRADVVLPNQFQALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPA
HHHHCCCCCCCCCCCEECCHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECEEEECCCC
NPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILTVAISWCINRLILHPLRNIAR
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNAIPAKELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLP
HHHCCCHHHHHCCHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEECCHHHCC
NKALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRM
CHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ILAQISGYDFAVIANGVQEPWHAITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDL
HHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEHHHHHCCH
TAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQP
HHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECC
QVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQ
CEEECCCCEEEEEHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAIL
HCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHH
RPLRNAGVRVALDDFGMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLA
HHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK
HHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 10493123