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The map label for this gene is yraR

Identifier: 157162637

GI number: 157162637

Start: 3349137

End: 3349772

Strand: Reverse

Name: yraR

Synonym: EcHS_A3344

Alternate gene names: 157162637

Gene position: 3349772-3349137 (Counterclockwise)

Preceding gene: 157162639

Following gene: 157162636

Centisome position: 72.14

GC content: 54.87

Gene sequence:

>636_bases
ATGAGTCAGGTACTGATTACAGGCGCAACGGGGCTGGTGGGCGGTCACCTGCTGCGGATGTTGATTAACGAACCGAAAGT
TAACGCCATTGCTGCGCCGACGCGACGTCCGTTGGGCGATATGCCCGGGGTGTTTAATCCCCATGATCCGCAACTGAGTG
ACGCGTTGGCGCAGGTCACCGATCCCATCGACATTGTGTTTTGTTGTCTCGGCACCACGCGGCGAGAAGCGGGGAGCAAA
GAGGCGTTTATTCATGCCGATTACACGCTGGTAGTGGATACCGCATTAACCGGGCGGCGACTGGGCGCGCAGCATATGTT
GGTAGTCAGTGCGATGGGTGCCAATGCCCACTCGCCGTTTTTCTATAACCGCGTCAAAGGGGAGATGGAAGAAGCATTAA
TCGCCCAGAACTGGCCGAAATTGACCATTGCTCGCCCGTCGATGTTACTGGGCGATCGTAGCAAACAGCGGATGAACGAA
ACGCTTTTTGCGCCGCTGTTCCGTTTGTTACCAGGTAACTGGAAATCCATTGATGCGAGAGACGTGGCGCGGGTCATGCT
GGCAGAGTCGATGCGGCCTGAGCATGAAGGCGTGACGATTTTAAGCTCTTCAGAATTACGCAAAAGAGCTGAATAA

Upstream 100 bases:

>100_bases
AGGCGAATTTCCCACAATCGGGGATAATTACCTCATGGTCTATTAAGCCTGGTGCATGAGCCGTGGAGCGCAAGGCAGAC
AATTCTGTAAAGGAGCGAAG

Downstream 100 bases:

>100_bases
TTATTCCCAAGAATTGATAGTGAGCGTAATATTCACGCGCTCAATTATCATAACTTATTCCTGGGGAATGCTATGACTGG
TCAGTCTTCATCTCAGGCGG

Product: NAD dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLSDALAQVTDPIDIVFCCLGTTRREAGSK
EAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
TLFAPLFRLLPGNWKSIDARDVARVMLAESMRPEHEGVTILSSSELRKRAE

Sequences:

>Translated_211_residues
MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLSDALAQVTDPIDIVFCCLGTTRREAGSK
EAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
TLFAPLFRLLPGNWKSIDARDVARVMLAESMRPEHEGVTILSSSELRKRAE
>Mature_210_residues
SQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLSDALAQVTDPIDIVFCCLGTTRREAGSKE
AFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNET
LFAPLFRLLPGNWKSIDARDVARVMLAESMRPEHEGVTILSSSELRKRAE

Specific function: Unknown

COG id: COG0702

COG function: function code MG; Predicted nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YER004W

Homologues:

Organism=Homo sapiens, GI148728172, Length=208, Percent_Identity=31.7307692307692, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI148728168, Length=208, Percent_Identity=31.7307692307692, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI148728164, Length=208, Percent_Identity=31.7307692307692, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI148728166, Length=211, Percent_Identity=31.2796208530806, Blast_Score=98, Evalue=5e-21,
Organism=Escherichia coli, GI87082218, Length=211, Percent_Identity=100, Blast_Score=435, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI71983631, Length=213, Percent_Identity=30.5164319248826, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320840, Length=160, Percent_Identity=30, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YRAR_ECOLI (P45469)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D65105
- RefSeq:   AP_003697.1
- RefSeq:   NP_417621.2
- ProteinModelPortal:   P45469
- SMR:   P45469
- DIP:   DIP-12902N
- STRING:   P45469
- EnsemblBacteria:   EBESCT00000001004
- EnsemblBacteria:   EBESCT00000014506
- GeneID:   947667
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5528
- KEGG:   eco:b3152
- EchoBASE:   EB2636
- EcoGene:   EG12783
- eggNOG:   COG0702
- GeneTree:   EBGT00050000010237
- HOGENOM:   HBG564164
- OMA:   HLENPVG
- ProtClustDB:   CLSK880609
- BioCyc:   EcoCyc:G7646-MONOMER
- Genevestigator:   P45469
- GO:   GO:0005737
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01118 Semialdhyde_dh

EC number: NA

Molecular weight: Translated: 23198; Mature: 23067

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLSDALAQVT
CCCEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHC
DPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPF
CHHHEEHHHCCCHHHHCCCCCEEEECCEEEEEECCCCCCCCCCHHEEEEEECCCCCCCCH
FYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNETLFAPLFRLLPGNWKSIDAR
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
DVARVMLAESMRPEHEGVTILSSSELRKRAE
HHHHHHHHHHCCCCCCCEEEEECHHHHHHCC
>Mature Secondary Structure 
SQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLSDALAQVT
CCEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHC
DPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPF
CHHHEEHHHCCCHHHHCCCCCEEEECCEEEEEECCCCCCCCCCHHEEEEEECCCCCCCCH
FYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNETLFAPLFRLLPGNWKSIDAR
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
DVARVMLAESMRPEHEGVTILSSSELRKRAE
HHHHHHHHHHCCCCCCCEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503