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The map label for this gene is ttdR [H]

Identifier: 157162534

GI number: 157162534

Start: 3248713

End: 3249162

Strand: Reverse

Name: ttdR [H]

Synonym: EcHS_A3238

Alternate gene names: 157162534

Gene position: 3249162-3248713 (Counterclockwise)

Preceding gene: 157162540

Following gene: 157162532

Centisome position: 69.97

GC content: 50.67

Gene sequence:

>450_bases
TTGACAAAAAATAAAAGAATATTATGCGCAGCACCTGAGTATCTGCAAAAATATCCGCAGCCACAATCCCTACAGGAATT
AAGTCGTCATGACTGTCTGGTGACCAAAGAGCGCGATATGACCCATGGAATATGGGAGTTGGGGAACGGTCAGGAGAAAA
AATCGGTGAAGGTAAGCGGGCATCTTTCCTCCAATAGCGGCGAGATTGTGCTGCAATGGGCGCTGGAGGGCAAAGGGATT
ATGCTGCGTTCCGAGTGGGATGTGTTGCCGTTTCTGGAGAGTGGCAAACTGGTGCAAGTATTGCCAGAGTATGCACAAAG
CGCCAATATCTGGGCTGTTTACCGGGAGCCGCTCTATCGCAGCATGAAATTACGTGTCTGCGTGGAATTTCTGGCGGCAT
GGTGCCAGCAACGGCTGGGCAAGCCCGATGAAGGCTATCAGGTCATGTAG

Upstream 100 bases:

>100_bases
TGAACAGGAGGGACAGCTGATAGAAACAGAAGCCACTGGAGCACCTCAAAAACACCATCATACACTAAATCAGTAAGTTG
GCAGCATCACCGCGCATCTT

Downstream 100 bases:

>100_bases
ATCCACCAGAAATCACTCGGGATCCTTTTCGCGCTTTCTTTTGAATTTCGTCCAGATTTTTGTCTCCTGACGACGCCACA
GACGTTGGATGTTGTCATGA

Product: transcriptional regulator, truncation

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGI
MLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYREPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM

Sequences:

>Translated_149_residues
MTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGI
MLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYREPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM
>Mature_148_residues
TKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIM
LRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYREPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=149, Percent_Identity=99.3288590604027, Blast_Score=312, Evalue=5e-87,
Organism=Escherichia coli, GI87081978, Length=131, Percent_Identity=54.1984732824427, Blast_Score=145, Evalue=1e-36,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 17140; Mature: 17009

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSG
CCCCCEEEEECHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCCHHCCCCCCCCCEEEEEE
HLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYREPLYR
EECCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHH
SMKLRVCVEFLAAWCQQRLGKPDEGYQVM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSG
CCCCEEEEECHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCCHHCCCCCCCCCEEEEEE
HLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYREPLYR
EECCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHH
SMKLRVCVEFLAAWCQQRLGKPDEGYQVM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]