BacMap

Definition	Escherichia coli HS, complete genome.
Accession	NC_009800
Length	4,643,538

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The map label for this gene is gudP [H]

Identifier: 157162243

GI number: 157162243

Start: 2938957

End: 2940309

Strand: Reverse

Name: gudP [H]

Synonym: EcHS_A2933

Alternate gene names: 157162243

Gene position: 2940309-2938957 (Counterclockwise)

Preceding gene: 157162244

Following gene: 157162242

Centisome position: 63.32

GC content: 52.4

Gene sequence:

>1353_bases
ATGAGTTCTTTAAGTCAGGCTGCGAGCAGTGTGGAAAAACGCACAAATGCTCGTTACTGGATAGTGGTGATGTTGTTTAT
CGTCACATCCTTCAACTACGGCGACCGCGCTACGCTCTCTATCGCCGGTTCGGAAATGGCCAAAGATATCGGCCTTGATC
CTGTGGGAATGGGCTATGTGTTCTCTGCTTTCTCATGGGCTTATGTTATCGGGCAGATCCCTGGTGGCTGGTTGCTGGAC
CGTTTTGGTTCAAAACGCGTCTACTTCTGGTCGATCTTTATCTGGTCGATGTTTACCTTGCTGCAAGGCTTCGTCGATAT
CTTTAGTGGATTCGGCATTATCGTTGCCCTGTTTACGCTGCGCTTCCTGGTCGGGCTTGCTGAAGCGCCATCTTTCCCCG
GCAACAGTCGCATTGTTGCGGCCTGGTTTCCGGCGCAGGAAAGGGGAACGGCGGTGTCGATTTTTAACTCCGCCCAATAC
TTCGCAACGGTTATCTTCGCGCCGATTATGGGCTGGCTGACGCATGAAGTGGGCTGGTCACACGTCTTCTTCTTTATGGG
CGGTCTGGGCATTGTCATCAGCTTTATCTGGTTGAAAGTCATCCACGAGCCAAATCAACATCCGGGCGTAAATCAGAAAG
AGCTGGAGTATATCGCCGCGGGTGGCGCGCTGATCAATATGGATCAGCAAAACACTAAAGTTAAAGTGCCGTTCAGCGTG
AAGTGGGGGCAGATCAAACAGCTGCTCGGGTCACGGATGATGATCGGCGTTTATATCGGTCAGTACTGTATCAACGCCCT
GACTTACTTCTTTATTACCTGGTTCCCGGTTTATCTGGTGCAGGCACGCGGGATGTCGATTCTGAAAGCGGGCTTTGTGG
CTTCCGTTCCGGCGGTTTGCGGTTTTATCGGCGGTGTGCTGGGTGGGATTATTTCCGACTGGCTGATGCGCCGCACGGGA
TCGCTGAACATTGCGCGTAAAACACCGATCGTAATGGGCATGTTGCTGTCGATGGTGATGGTGTTCTGCAACTACGTCAA
CGTTGAGTGGATGATCATCGGCTTTATGGCGCTGGCCTTCTTCGGTAAGGGCATCGGGGCGCTGGGTTGGGCAGTAATGG
CAGATACCGCGCCAAAAGAGATCAGCGGTCTTTCCGGTGGCCTGTTCAACATGTTCGGTAACATTTCTGGCATCGTCACG
CCAATCGCAATTGGTTATATCGTTGGCACGACTGGCTCCTTTAATGGGGCGCTGATTTATGTTGGTGTTCATGCCTTAAT
CGCGGTACTGAGCTACCTGGTGCTGGTGGGCGATATCAAGCGTATCGAGCTGAAACCTGTCGCGGGGCAATAA

Upstream 100 bases:

>100_bases
CTATAAAAACGGCAAAAAACACCCTACGTCACCTCTGATTTCCTGGCGATGTCGCAGTCCAGAGTGAGCGTGGCTAACGC
GAATTTTCAGGAGTGCAACA

Downstream 100 bases:

>100_bases
GATGACGACACAATCCAGTCCTGTTATTACTGATATGAAAGTCATTCCGGTCGCCGGGCACGATAGCATGTTGCTTAATA
TTGGTGGGGCACATAACGCA

Product: glucarate permease

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLD
RFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSV
KWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTG
SLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVT
PIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ

Sequences:

>Translated_450_residues
MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLD
RFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSV
KWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTG
SLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVT
PIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
>Mature_449_residues
SSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDR
FGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYF
ATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVK
WGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGS
LNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTP
IAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=409, Percent_Identity=27.6283618581907, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI9945322, Length=409, Percent_Identity=28.1173594132029, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI21322234, Length=413, Percent_Identity=25.6658595641646, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI148743791, Length=395, Percent_Identity=25.3164556962025, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4885441, Length=379, Percent_Identity=25.8575197889182, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI6912666, Length=371, Percent_Identity=25.8760107816712, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI5031955, Length=269, Percent_Identity=26.0223048327138, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI154350196, Length=421, Percent_Identity=23.5154394299287, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI148728191, Length=306, Percent_Identity=24.8366013071895, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI256219598, Length=379, Percent_Identity=23.4828496042216, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4503847, Length=379, Percent_Identity=23.4828496042216, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI256219483, Length=379, Percent_Identity=23.4828496042216, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI223718438, Length=218, Percent_Identity=27.5229357798165, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI256219543, Length=295, Percent_Identity=25.0847457627119, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI256219564, Length=309, Percent_Identity=22.9773462783171, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789152, Length=450, Percent_Identity=99.7777777777778, Blast_Score=896, Evalue=0.0,
Organism=Escherichia coli, GI1789515, Length=434, Percent_Identity=57.6036866359447, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI87082320, Length=435, Percent_Identity=42.2988505747126, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI2367379, Length=419, Percent_Identity=28.8782816229117, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI2367193, Length=435, Percent_Identity=23.2183908045977, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788573, Length=452, Percent_Identity=22.3451327433628, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082071, Length=421, Percent_Identity=23.5154394299287, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=433, Percent_Identity=28.4064665127021, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI115533554, Length=431, Percent_Identity=27.6102088167053, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17552542, Length=414, Percent_Identity=24.8792270531401, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71991448, Length=375, Percent_Identity=24, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71991453, Length=375, Percent_Identity=24, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535049, Length=433, Percent_Identity=22.4018475750577, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560030, Length=400, Percent_Identity=24.5, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193205400, Length=302, Percent_Identity=22.8476821192053, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17569727, Length=384, Percent_Identity=23.9583333333333, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32565916, Length=256, Percent_Identity=24.21875, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32565914, Length=362, Percent_Identity=22.9281767955801, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17554148, Length=355, Percent_Identity=23.6619718309859, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17532009, Length=414, Percent_Identity=21.9806763285024, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25145964, Length=286, Percent_Identity=22.3776223776224, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71997452, Length=320, Percent_Identity=20.625, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509575, Length=236, Percent_Identity=26.271186440678, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534558, Length=248, Percent_Identity=25.4032258064516, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71989129, Length=263, Percent_Identity=25.0950570342205, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534592, Length=226, Percent_Identity=25.6637168141593, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560966, Length=324, Percent_Identity=22.5308641975309, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25151055, Length=242, Percent_Identity=21.4876033057851, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17570335, Length=242, Percent_Identity=21.900826446281, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI45550460, Length=423, Percent_Identity=26.0047281323877, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24655255, Length=361, Percent_Identity=27.4238227146814, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24641682, Length=383, Percent_Identity=25.8485639686684, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24583789, Length=405, Percent_Identity=25.679012345679, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24639764, Length=429, Percent_Identity=22.6107226107226, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI20130135, Length=407, Percent_Identity=25.5528255528256, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20130167, Length=426, Percent_Identity=26.9953051643192, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24654215, Length=449, Percent_Identity=24.7216035634744, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24655271, Length=407, Percent_Identity=25.3071253071253, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922400, Length=433, Percent_Identity=24.9422632794457, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24648416, Length=461, Percent_Identity=24.295010845987, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356189, Length=461, Percent_Identity=24.295010845987, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24584153, Length=399, Percent_Identity=25.062656641604, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI62484226, Length=407, Percent_Identity=25.7985257985258, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573708, Length=432, Percent_Identity=22.6851851851852, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573707, Length=432, Percent_Identity=22.6851851851852, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24580790, Length=389, Percent_Identity=23.9074550128535, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI20129235, Length=375, Percent_Identity=27.2, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573299, Length=408, Percent_Identity=24.7549019607843, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24658674, Length=359, Percent_Identity=25.0696378830084, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221474708, Length=164, Percent_Identity=32.9268292682927, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24658666, Length=407, Percent_Identity=23.3415233415233, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653727, Length=367, Percent_Identity=23.7057220708447, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550495, Length=363, Percent_Identity=23.1404958677686, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24658658, Length=409, Percent_Identity=21.760391198044, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281361682, Length=361, Percent_Identity=22.4376731301939, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24658696, Length=411, Percent_Identity=24.0875912408759, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49143; Mature: 49012

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCCCHHHH
FSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTL
HHHHHHHHHHHCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWS
HHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHH
HVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCEEEEEEEC
KWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVC
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAF
HHHHHHHHHHHHHHHHHHCCCCEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIY
HHCCHHHHHHHHHCCCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHHEECCCCCCCEEEH
VGVHALIAVLSYLVLVGDIKRIELKPVAGQ
HHHHHHHHHHHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure 
SSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYV
CHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCCCHHHH
FSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTL
HHHHHHHHHHHCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWS
HHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHH
HVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCEEEEEEEC
KWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVC
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAF
HHHHHHHHHHHHHHHHHHCCCCEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIY
HHCCHHHHHHHHHCCCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHHEECCCCCCCEEEH
VGVHALIAVLSYLVLVGDIKRIELKPVAGQ
HHHHHHHHHHHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]