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The map label for this gene is yphH [H]

Identifier: 157162027

GI number: 157162027

Start: 2721197

End: 2722390

Strand: Direct

Name: yphH [H]

Synonym: EcHS_A2703

Alternate gene names: 157162027

Gene position: 2721197-2722390 (Clockwise)

Preceding gene: 157162018

Following gene: 157162029

Centisome position: 58.6

GC content: 51.42

Gene sequence:

>1194_bases
ATGAGAGCCTGCATTAACAATCAACAGATTCGCCACAATAACAAATGCGTGATTCTGGAACTGCTGTACCGGCAAAAGCG
CGCCAATAAATCAACGCTGGCCCGGCTGGCGCAAATTTCGATTCCGGCGGTCAGTAATATTTTGCAGGAACTGGAAAGCG
AAAAACGGGTGGTGAATATCGACGATGAAAGTCAGACGCGCGGGCATAGTAGCGGTACATGGCTGATTGCGCCGGAAGGT
GACTGGACGCTGTGCCTGAACGTGACGCCCACCAGTATTGAGTGTCAGGTTGCTAATGCTTGTTTAAGTCCGAAAGGCGA
GTTTGAGTATTTACAGATTGATGCACCGACGCCGCAGGCGCTGCTGTCCGAAATCGAAAAATGCTGGCATCGCCACCGTA
AATTGTGGCCGGACCGTACCATCAACCTGGCGCTGGCAATCCACGGTCAGGTTGATCCGGTGACCGGCGTGTCGCAAACC
ATGCCGCAAGCGCCGTGGACAACGCCGGTTGAGGTAAAGTATCTGCTGGAAGAGAAGCTCGGCATTCGGGTGATGGTCGA
TAATGACTGCGTGATGCTGGCGCTCGCGGAGAAATGGCAAAATAATTCGCAGGAACGGGATTTCTGCGTGATCAACGTTG
ATTACGGCATTGGCTCGTCGTTCGTGATTAACGAGCAAATTTATCGCGGCAGTTTGTATGGTAGCGGACAGATTGGTCAC
ACCATCGTTAATCCGGATGGCGTCGTCTGCGACTGTGGACGTTACGGCTGCCTGGAAACCGTCGCCTCGTTAAGCGCATT
AAAAAAACAGGCGCGGGTATGGCTAAAATCACAACCGGTTAGTACTCAACTTGATCCTGAAAAACTGACTACAGCGCAGT
TAATCGCTGCCTGGCAAAGTGGAGAACCGTGGGTCACCAGCTGGGTTGACCGCAGTGCCAATGCCATTGGTTTGAGTCTG
TATAACTTCCTCAACATCCTCAATATTAATCAGATTTGGTTGTACGGTCGCAGTTGTGCCTTTGGTGAGAACTGGCTTAA
TACTATTATTCGCCAGACAGGATTTAACCCGTTCGACCGCGACGAAGGACCGAGCGTGAAAGCGACGCAAATTGGCTTCG
GGCAATTAAGCCGCGCACAACAGGTGCTGGGAATTGGCTATTTGTATGTTGAGGCGCAGTTACGACAGATTTGA

Upstream 100 bases:

>100_bases
CAAGACATACTGAATTAAAAGATTTGTGGCAGTGTATTGAACAATCTGGCAATGTTTTCGCGGAATAATCACGCAATTAA
CTAAACAAGGTTTAGTGAAG

Downstream 100 bases:

>100_bases
TGGCGCGATAACGTAGAAAGGCTTCCCGAAGGAAGCCTTGATGATCATAAACGAAAAATCGCCTGATGCGCTACGCTTAT
CAGGCCTACACGGAGATTGC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MRACINNQQIRHNNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEG
DWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVSTQLDPEKLTTAQLIAAWQSGEPWVTSWVDRSANAIGLSL
YNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI

Sequences:

>Translated_397_residues
MRACINNQQIRHNNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEG
DWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVSTQLDPEKLTTAQLIAAWQSGEPWVTSWVDRSANAIGLSL
YNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI
>Mature_397_residues
MRACINNQQIRHNNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEG
DWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVSTQLDPEKLTTAQLIAAWQSGEPWVTSWVDRSANAIGLSL
YNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=222, Percent_Identity=27.9279279279279, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI298566325, Length=222, Percent_Identity=27.9279279279279, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI190014632, Length=222, Percent_Identity=27.9279279279279, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4885285, Length=222, Percent_Identity=27.9279279279279, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87082127, Length=397, Percent_Identity=99.2443324937028, Blast_Score=815, Evalue=0.0,
Organism=Escherichia coli, GI1787878, Length=333, Percent_Identity=24.6246246246246, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786891, Length=222, Percent_Identity=28.8288288288288, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44503; Mature: 44503

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRACINNQQIRHNNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNI
CCCCCCCCCEECCCCEEEEHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEC
DDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDAPTPQA
CCCHHCCCCCCCEEEEEECCCEEEEEEECCCCEEEEEEHHHCCCCCCEEEEEECCCCHHH
LLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQTMPQAPWTTPVEVKYLLEEKL
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHHHEEEHHCC
GIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
CEEEEECCCEEEEEEHHHHCCCCCCCCEEEEEECCCCCCEEEEECHHEECCCCCCCCCCC
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVSTQLDPEKLTTAQLIAAWQS
EEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCC
GEPWVTSWVDRSANAIGLSLYNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDR
CCCHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
DEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI
CCCCCEEEEEECCHHHHHHHHHHHEEEEEEEEHHHCC
>Mature Secondary Structure
MRACINNQQIRHNNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNI
CCCCCCCCCEECCCCEEEEHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEC
DDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDAPTPQA
CCCHHCCCCCCCEEEEEECCCEEEEEEECCCCEEEEEEHHHCCCCCCEEEEEECCCCHHH
LLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQTMPQAPWTTPVEVKYLLEEKL
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHHHEEEHHCC
GIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
CEEEEECCCEEEEEEHHHHCCCCCCCCEEEEEECCCCCCEEEEECHHEECCCCCCCCCCC
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVSTQLDPEKLTTAQLIAAWQS
EEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCC
GEPWVTSWVDRSANAIGLSLYNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDR
CCCHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
DEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI
CCCCCEEEEEECCHHHHHHHHHHHEEEEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]