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The map label for this gene is yfhR [H]

Identifier: 157162010

GI number: 157162010

Start: 2701947

End: 2702801

Strand: Direct

Name: yfhR [H]

Synonym: EcHS_A2686

Alternate gene names: 157162010

Gene position: 2701947-2702801 (Clockwise)

Preceding gene: 157162009

Following gene: 157162013

Centisome position: 58.19

GC content: 50.99

Gene sequence:

>855_bases
ATGGCACTGCCAGTGAACAAACGCGTTCCCAAAATTCTGTTTATTCTCTTTGTTGTTGCCTTCTGCGTTTATTTAGTGCC
GCGCGTTGCCATCAACTTCTTCTATTATCCTGACGATAAAATTTACGGTCCCGACCCCTGGTCGGCGGAATCCGTCGAAT
TTACGGCTAAGGACGGTACTCGTCTGCAAGGCTGGTTTATCCCTTCTTCGACGGGCCCTGCTGACAACGCCATCGCAACC
ATCATTCATGCTCACGGCAATGCCGGAAATATGTCCGCCCACTGGCCGCTGGTCAGTTGGTTACCCGAGCGTAATTTCAA
CGTTTTTATGTTTGATTATCGCGGGTTTGGTAAATCAAAAGGCACGCCGTCCCAGGCCGGATTGCTGGACGATACGCAAA
GCGCCATCAATGTGGTGCGCCATCGCAGTGATGTAAACCCACAACGGCTGGTGCTGTTCGGGCAGAGTATTGGCGGGGCG
AATATTCTTGCTGTTATTGGTCAGGGTGATCGTGAAGGCATACGTGCGGTGATCCTCGACTCCACATTTGCCTCTTATGC
AACCATCGCCAACCAGATGATCCCCGGCAGTGGCTACTTACTTGATGAGAGTTACAGCGGCGAAAATTACATCGCCAGCG
TCAGCCCGATCCCGCTTTTACTCATTCACGGTAAAGCCGATCACGTTATCCCATGGCAGCACAGCGAAAAGTTGTATAGC
CTGGCAAAAGAGCCAAAACGGTTGATCCTAATCCCGGATGGCGAACACATTGATGCTTTTTCCGATCGTCACGGCGATGT
TTATCGCGAACAGATGGTGGACTTTATCCTTAGCGCGTTGAATCCGCAGAACTAA

Upstream 100 bases:

>100_bases
CGCTATTCCGAAATACTTCCTCACCGCTTTACTTTCTTTCGTCACTCTCCCACCATCTTTCCCCGATTAATGGATGATAA
AGAAGTCGCAAGGAAAGGTT

Downstream 100 bases:

>100_bases
CCCATGATCGCTAGCACGATAATCATTCACAAAACCACCTTAAGACATGCTAATCCACTGGTCAGAACAGTTTAAGATGA
GAAAAATTCTGTGACGCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIAT
IIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
NILAVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIPWQHSEKLYS
LAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN

Sequences:

>Translated_284_residues
MALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIAT
IIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
NILAVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIPWQHSEKLYS
LAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN
>Mature_283_residues
ALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIATI
IHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGAN
ILAVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIPWQHSEKLYSL
AKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine esterase family [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=265, Percent_Identity=29.4339622641509, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI71051602, Length=225, Percent_Identity=28.4444444444444, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI71051600, Length=225, Percent_Identity=28.4444444444444, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI151301175, Length=207, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI194306564, Length=235, Percent_Identity=28.5106382978723, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI194306562, Length=214, Percent_Identity=29.4392523364486, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI32451492, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI32528310, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI24308097, Length=181, Percent_Identity=31.4917127071823, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI109689718, Length=181, Percent_Identity=31.4917127071823, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI226510965, Length=284, Percent_Identity=99.2957746478873, Blast_Score=580, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI71988362, Length=206, Percent_Identity=28.1553398058252, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324009, Length=233, Percent_Identity=30.0429184549356, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17137566, Length=299, Percent_Identity=28.4280936454849, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281362521, Length=236, Percent_Identity=25.8474576271186, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281362519, Length=236, Percent_Identity=25.8474576271186, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571878, Length=236, Percent_Identity=25.8474576271186, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 31444; Mature: 31313

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEECCCC
RLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSK
EEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHEECCCCCCEEEEEEECCCCCCC
GTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGANILAVIGQGDREGIRAVILD
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCEEEEEE
STFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIPWQHSEKLYS
CHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCCEEEEEECCCCCCCCCCCHHHHHH
LAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEECCCC
RLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSK
EEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHEECCCCCCEEEEEEECCCCCCC
GTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGANILAVIGQGDREGIRAVILD
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCEEEEEE
STFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIPWQHSEKLYS
CHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCCEEEEEECCCCCCCCCCCHHHHHH
LAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFILSALNPQN
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]