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The map label for this gene is ypdA

Identifier: 157161853

GI number: 157161853

Start: 2530091

End: 2531770

Strand: Direct

Name: ypdA

Synonym: EcHS_A2517

Alternate gene names: 157161853

Gene position: 2530091-2531770 (Clockwise)

Preceding gene: 157161851

Following gene: 157161854

Centisome position: 54.49

GC content: 51.43

Gene sequence:

>1680_bases
ATGCTGCTGGCGGTCTTCGATCGGGCAGCGTTAATGCTTATCTGCCTGTTCTTTCTCATCCGTATCCGCCTGTTTCGCGA
ACTGTTGCACAAGTCGGCGCACTCCCCAAAAGAATTGCTCGCCGTTACCGCCATTTTCTCGCTGTTCGCCCTGTTCAGCA
CCTGGTCCGGCGTTCCCGTAGAAGGCTCACTGGTGAACGTACGTATTATCGCGGTGATGTCCGGCGGGATTCTGTTTGGC
CCGTGGGTAGGCATCATTACCGGCGTGATTGCGGGTATTCACCGGTATTTAATTGATATCGGCGGCGTGACGGCGATCCC
CTGCTTTATCACCAGCATTCTGGCGGGTTGTATATCGGGCTGGATCAACCTGAAAATCCCCAAAGCACAGCGCTGGCGCG
TCGGTATTCTCGGCGGCATGTTGTGTGAGACGTTGACCATGATTCTGGTAATTGTCTGGGCACCAACTACCGCGTTGGGG
ATCGATATCGTCTCTAAAATCGGCATTCCAATGATCCTCGGTAGCGTCTGTATCGGCTTTATTGTGCTTCTGGTGCAAAG
CGTTGAGGGCGAAAAAGAGGCCAGCGCCGCGCGGCAGGCCAAGCTGGCGCTGGATATCGCCAACAAAACGCTACCGCTGT
TTCGCCATGTCAATAGCGAGTCATTACGCAAGGTCTGCGAAATTATCCGCGATGACATTCACGCCGATGCGGTGGCGATT
ACTAATACCGATCATGTGCTGGCCTATGTTGGCGTGGGTGAACATAACTATCAGAATGGCGATGACTTCATTAGCCCGAC
TACCCGTCAGGCGATGAATTACGGAAAAATCATCATTAAAAACAATGATGAAGCCCACCGCACACCAGAGATTCATTCCA
TGCTGGTGATCCCATTGTGGGAGAAAGGGGTCGTGACCGGAACGCTGAAAATTTACTACTGCCACGCGCATCAGATCACC
TCGTCATTACAGGAAATGGCGGTCGGTCTGTCGCAAATCATCTCCACGCAACTGGAGGTTTCACGCGCCGAGCAGCTACG
TGAAATGGCAAATAAGGCAGAGCTTCGCGCCCTGCAAAGCAAAATTAATCCCCATTTTCTGTTTAACGCTCTGAACGCTA
TTTCATCGTCAATCCGTCTGAATCCGGATACCGCTCGCCAGTTGATCTTTAATCTGTCGCGTTATCTGCGCTATAACATT
GAATTAAAAGACGATGAGCAAATCGATATCAAAAAAGAGCTGTATCAAATTAAAGACTATATTGCCATTGAGCAGGCCCG
CTTTGGTGACAAGCTGACGGTTATCTATGATATTGATGAAGAGGTGAATTGCTGCATTCCCAGCCTGCTGATCCAGCCGT
TGGTGGAGAACGCCATTGTCCACGGTATTCAGCCTTGCAAAGGTAAAGGCGTTGTCACCATCAGTGTTGCAGAGTGCGGA
AATCGGGTACGCATTGCGGTGCGAGATACCGGGCACGGCATCGATCCAAAGGTGATTGAGCGGGTCGAAGCGAATGAAAT
GCCGGGCAATAAAATTGGCCTGCTGAATGTCCATCATCGCGTGAAGTTATTGTATGGCGAGGGGCTGCATATCCGCCGCC
TGGAGCCGGGGACGGAAATTGCGTTTTACATTCCTAACCAACGCACCCCAGTCGCCTCACAGGCTACGTTATTGCTTTGA

Upstream 100 bases:

>100_bases
GGTTTTTCCTCAAAAACGGCCTGCTGGTCATCAGCCTTCAGGTTACCTATCATAGAGGTTTAATCCTTATTCAGAGTCAC
CCGTGCACGAAATATTCAAC

Downstream 100 bases:

>100_bases
GCCGGAGTGATATTGTGAAAGTCATCATTGTTGAAGACGAATTCCTGGCACAACAGGAACTGAGCTGGCTAATTAAAGAG
CACAGCCAGATGGAGATTGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFG
PWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALG
IDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAI
TNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQIT
SSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNI
ELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECG
NRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL

Sequences:

>Translated_559_residues
MLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFG
PWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALG
IDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAI
TNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQIT
SSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNI
ELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECG
NRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL
>Mature_559_residues
MLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFG
PWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALG
IDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAI
TNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQIT
SSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNI
ELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECG
NRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL

Specific function: Unknown

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788723, Length=559, Percent_Identity=100, Blast_Score=1142, Evalue=0.0,
Organism=Escherichia coli, GI1788446, Length=514, Percent_Identity=28.7937743190661, Blast_Score=197, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YPDA_ECO57 (P0AA94)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D91036
- PIR:   F85880
- RefSeq:   NP_288950.1
- RefSeq:   NP_311287.1
- ProteinModelPortal:   P0AA94
- SMR:   P0AA94
- EnsemblBacteria:   EBESCT00000028016
- EnsemblBacteria:   EBESCT00000059631
- GeneID:   915638
- GeneID:   957579
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3645
- KEGG:   ecs:ECs3260
- GeneTree:   EBGT00050000008644
- HOGENOM:   HBG724694
- OMA:   VIYDIDD
- ProtClustDB:   CLSK880374
- BioCyc:   ECOL83334:ECS3260-MONOMER
- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00065
- SMART:   SM00387

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase; SSF55874 ATP_bd_ATPase

EC number: 2.7.3.-

Molecular weight: Translated: 61887; Mature: 61887

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16454b84)-; HASH(0x163dba04)-; HASH(0x15c999a4)-; HASH(0x15bd506c)-; HASH(0x163d1438)-; HASH(0x162f7868)-;

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPV
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISG
CCCEEEEEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
WINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALGIDIVSKIGIPMILGSVCIGF
CEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
IVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAI
HHHHHHHCCCCHHHHHHHHHHHHEECCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEE
TNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLW
ECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCHHCEEEEEEC
EKGVVTGTLKIYYCHAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQS
CCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDY
HCCHHHHHHHHHHHHHCEEECHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHH
IAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECG
HHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCC
NRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEI
CEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEECEEEEEEECCCEEEEEECCCCEE
AFYIPNQRTPVASQATLLL
EEEECCCCCCCCCCCEECH
>Mature Secondary Structure
MLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPV
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISG
CCCEEEEEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
WINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALGIDIVSKIGIPMILGSVCIGF
CEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
IVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAI
HHHHHHHCCCCHHHHHHHHHHHHEECCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEE
TNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLW
ECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCHHCEEEEEEC
EKGVVTGTLKIYYCHAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQS
CCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDY
HCCHHHHHHHHHHHHHCEEECHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHH
IAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECG
HHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCC
NRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEI
CEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEECEEEEEEECCCEEEEEECCCCEE
AFYIPNQRTPVASQATLLL
EEEECCCCCCCCCCCEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796