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The map label for this gene is gatY [H]

Identifier: 157161580

GI number: 157161580

Start: 2218699

End: 2219553

Strand: Reverse

Name: gatY [H]

Synonym: EcHS_A2232

Alternate gene names: 157161580

Gene position: 2219553-2218699 (Counterclockwise)

Preceding gene: 157161581

Following gene: 157161579

Centisome position: 47.8

GC content: 53.1

Gene sequence:

>855_bases
ATGTACGTGGTATCGACAAAGCAGATGCTGAACAACGCACAGCGCGGCGGTTATGCGGTTCCGGCATTCAATATTCACAA
TCTCGAAACGATGCAAGTGGTGGTAGAAACCGCTGCCAACCTGCATGCGCCGGTCATCATCGCCGGAACGCCTGGCACAT
TTACTCATGCTGGTACAGAAAATCTGTTGGCGCTGGTCAGCGCGATGGCGAAGCAATATCACCATCCACTGGCAATTCAT
CTCGACCATCACACGAAATTTGACGATATCGCTCAGAAGGTTCGTTCTGGCGTGCGCTCAGTCATGATTGACGCCTCGCA
TTTGCCTTTTGCGCAAAATATTTCACGGGTCAAAGAGGTGGTGGATTTTTGCCATCGCTTTGATGTCAGCGTCGAGGCGG
AGCTGGGGCAACTTGGCGGCCAGGAAGATGATGTGCAAGTCAATGAAGCCGATGCGTTGTACACCAACCCCGCTCAGGCG
CGTGAATTTGCCGAGGCAACCGGAATTGATTCCCTGGCGGTCGCCATCGGCACGGCTCATGGGATGTATGCCAGCGCACC
GGCGCTTGATTTTTCTAGACTGGAGAACATTCGCCAGTGGGTGAACTTACCGCTGGTGCTGCATGGCGCGTCAGGGTTAT
CGACTAAGGATATTCAGCAAACCATCAAACTGGGGATATGCAAAATCAACGTTGCAACGGAGCTGAAAAATGCCTTCTCG
CAGGCGTTAAAAAATTACCTGACCGAGCACCCTGAAGCGACCGATCCCCGGGATTATTTGCAGTCGGCTAAATCCGCAAT
GCGCGATGTGGTGAGCAAAGTGATTGCCGATTGTGGCTGCGAGGGCAGGGCATAA

Upstream 100 bases:

>100_bases
ACAATTTTCATATTGTCGTTTTTGTGATCGTTATCTCGATATTTAAAAACAAATAATTTCATTATATTTTGAAATCGAAA
ACAAACGACAGGATATGAAA

Downstream 100 bases:

>100_bases
CGCACCTGCCATTTAACAAGGAAAAAACATGAAAACGTTAATTGCCCGGCATAAAGCTGGTGAACATATCGGCATATGTT
CAGTCTGTTCTGCCCATCCG

Product: tagatose-bisphosphate aldolase

Products: NA

Alternate protein names: TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIH
LDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQA
REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA

Sequences:

>Translated_284_residues
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIH
LDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQA
REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
>Mature_284_residues
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIH
LDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQA
REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA

Specific function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (T

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=284, Percent_Identity=100, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI1789526, Length=283, Percent_Identity=54.7703180212014, Blast_Score=334, Evalue=4e-93,
Organism=Escherichia coli, GI1788072, Length=234, Percent_Identity=42.3076923076923, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1789293, Length=324, Percent_Identity=24.3827160493827, Blast_Score=88, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322790, Length=329, Percent_Identity=24.3161094224924, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000771
- InterPro:   IPR011288 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 30812; Mature: 30812

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTE
CEEECHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
NLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEV
HHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQAREFAEATGIDSLAVAIGTAH
HHHHHHCCCCEEHHHHHCCCCCCCCEECCCCCEECCHHHHHHHHHHHCCHHHHHHHHHHC
GMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHH
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTE
CEEECHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
NLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEV
HHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQAREFAEATGIDSLAVAIGTAH
HHHHHHCCCCEEHHHHHCCCCCCCCEECCCCCEECCHHHHHHHHHHHCCHHHHHHHHHHC
GMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHH
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA