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The map label for this gene is yegL

Identifier: 157161564

GI number: 157161564

Start: 2196710

End: 2197369

Strand: Reverse

Name: yegL

Synonym: EcHS_A2215

Alternate gene names: 157161564

Gene position: 2197369-2196710 (Counterclockwise)

Preceding gene: 157161572

Following gene: 157161563

Centisome position: 47.32

GC content: 51.06

Gene sequence:

>660_bases
ATGAGCGAACAAATCACGTTTGCCACCAGCGATTTTGCCAGTAACCCGGAACCACGTTGCCCCTGCATTTTGCTGCTGGA
TGTTTCTGGTTCTATGAACGGTAGACCTATTAATGAACTTAACGCCGGATTGGTTACCTTTCGTGATGAACTGCTTGCTG
ATCCGCTGGCTTTAAAAAGAGTGGAACTCGGCATTGTGACGTTCGGCCCGGTGCATGTGGAACAACCCTTTACCAGCGCC
GCTAATTTTTTTCCGCCCATCCTGTTTGCCCAGGGCGATACACCAATGGGTGCGGCCATTACCAAAGCCCTGGATATGGT
AGAGGAGCGGAAACGTGAGTATCGTGCAAATGGTATTTCGTATTATCGCCCGTGGATTTTCCTGATTACCGATGGTGCAC
CAACCGATGAGTGGCAGGCTGCAGCCAACAAAGTGTTTCGGGGGGAAGAAGATAAAAGGTTTGCTTTCTTTTCCATCGGT
GTTCAGGGGGCGGATATGAAGACGCTGGCACAAATTAGCGTTCGTCAGCCTTTGCCTCTGCAAGGATTACAATTCCGTGA
ACTGTTTAGCTGGTTATCCAGTTCGCTGCGTTCGGTTTCCCGCTCCACGCCGGGAACGGAAGTTGTGCTGGAAGCGCCAA
AAGGCTGGACGTCAGTGTGA

Upstream 100 bases:

>100_bases
CCGCCGGGCCTAATTCTGAAAGTTTCTTCGTTTGCTCTTATTTCATTATTGCAGTCGGTATGATACCGGACCTCGATAAT
TCTCTAAGAAAGGATTTCTT

Downstream 100 bases:

>100_bases
GCTGGCGTCTGGTCTATGCATCAACCGTTGGAACGTCGCACATCAGCGCGGACTTGCCTTGTCAGGATGCCTGCCAGATG
CAGATTGCCTGGTTAAATGA

Product: von Willebrand factor type A domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGLVTFRDELLADPLALKRVELGIVTFGPVHVEQPFTSA
ANFFPPILFAQGDTPMGAAITKALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFRGEEDKRFAFFSIG
VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTSV

Sequences:

>Translated_219_residues
MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGLVTFRDELLADPLALKRVELGIVTFGPVHVEQPFTSA
ANFFPPILFAQGDTPMGAAITKALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFRGEEDKRFAFFSIG
VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTSV
>Mature_218_residues
SEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGLVTFRDELLADPLALKRVELGIVTFGPVHVEQPFTSAA
NFFPPILFAQGDTPMGAAITKALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFRGEEDKRFAFFSIGV
QGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTSV

Specific function: Unknown

COG id: COG4245

COG function: function code R; Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain

Homologues:

Organism=Escherichia coli, GI1788388, Length=219, Percent_Identity=100, Blast_Score=449, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEGL_ECOLI (P76396)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   H64973
- RefSeq:   AP_002673.1
- RefSeq:   NP_416577.1
- ProteinModelPortal:   P76396
- DIP:   DIP-11882N
- STRING:   P76396
- EnsemblBacteria:   EBESCT00000002952
- EnsemblBacteria:   EBESCT00000014796
- GeneID:   946602
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2058
- KEGG:   eco:b2073
- EchoBASE:   EB3808
- EcoGene:   EG14055
- eggNOG:   COG4245
- GeneTree:   EBGT00050000009759
- HOGENOM:   HBG284962
- OMA:   FSDTENG
- ProtClustDB:   CLSK880283
- BioCyc:   EcoCyc:G7112-MONOMER
- Genevestigator:   P76396
- InterPro:   IPR011392
- InterPro:   IPR002035
- PIRSF:   PIRSF020634
- SMART:   SM00327

Pfam domain/function: PF00092 VWA

EC number: NA

Molecular weight: Translated: 24218; Mature: 24087

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGLVTFRDELLADPLALKR
CCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHCHHHHHH
VELGIVTFGPVHVEQPFTSAANFFPPILFAQGDTPMGAAITKALDMVEERKREYRANGIS
EEEEEEEECCEECCCCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCE
YYRPWIFLITDGAPTDEWQAAANKVFRGEEDKRFAFFSIGVQGADMKTLAQISVRQPLPL
EECCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCC
QGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTSV
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
SEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGLVTFRDELLADPLALKR
CCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHCHHHHHH
VELGIVTFGPVHVEQPFTSAANFFPPILFAQGDTPMGAAITKALDMVEERKREYRANGIS
EEEEEEEECCEECCCCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCE
YYRPWIFLITDGAPTDEWQAAANKVFRGEEDKRFAFFSIGVQGADMKTLAQISVRQPLPL
EECCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCC
QGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTSV
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503