Click here to switch to the map view.

The map label for this gene is sohB [C]

Identifier: 157161458

GI number: 157161458

Start: 2075189

End: 2076055

Strand: Reverse

Name: sohB [C]

Synonym: EcHS_A2091

Alternate gene names: 157161458

Gene position: 2076055-2075189 (Counterclockwise)

Preceding gene: 157161459

Following gene: 157161457

Centisome position: 44.71

GC content: 54.09

Gene sequence:

>867_bases
GTGAATCTACCTCATCTGGCCCAGCGCCTTTTTAATACACCGCTGGCGCTGCACCCAAGTAAAGCTGAAGTCATCATGGC
ATCCGTTATGGACCGGTTTGGCATCAGTAAAATCGAATCCTCTCTTGCCATGGATGATGACTGGTATGGATACGACGATA
ACAGGGGGCGGGAATCCCGTAGCGACCCGGGTTATGACAATGTGTTGGGCGTCGCTGTCATCCCGATATGTGGGACCCTG
GTGCAGAAGCTGGGTAGCCTGCGCCCATACAGTGGCATGACAGGCTATGACGGCATTCGTCAGGCCTTCCTGACTGCGAT
GGAAGACCCCGATATTACAGGGATCTGCCTGGATATTGATTCGCCAGGAGGCGAGGTCGCCGGATGTTTCGATCTGGTCG
ATGTCATTTATGGCGCCCGCGGGAAAAAGCCCATCCATGCCATTCTGACGGAAAGCGCCTATTCCGCCGCCTATGCGATT
GCCAGTGCGGCGGACCGGATTTCTGTTCCCCGAACCGCTGGTGTGGGTTCAGTTGGTGTGATCACTATGCACCTTGACTG
GACCCAGCGGATAAAAGATGACGGCCTCAAAGTCACCATCATCACCTACGGTTCCCGTAAGGCTGAGGGGGCACCGCTGA
GAGAGCTGTCAGATGAAGCGCTGGCGGCTATTCAGCAGGACATCAACACCATGGGCGAATTGTTTGTGAATACCGTCGCC
AGAAATCGGGGGATTAGCGCAAAGGTTATCAAAAGTACTCAGGCTGCCTGTTTTATGGCTGCTGATGGTGTGGAACTTGG
ACTGGCTGATGAGGTGTGTCCTCCTGATGCTGCGTTCAGAAACTTACTTGAAAAAACAGGAGCCTGA

Upstream 100 bases:

>100_bases
AGCGGGAAATTGAGTCCTGCCTGAAGCGCGGACTTCCATTACCTAGCTGGGCGCAGGCGGACCAGTTCGCCAGCCAGACA
ATTACCGATCCGGAGGAAAA

Downstream 100 bases:

>100_bases
AATGGCGAAGAAAAAGACTTTTAGTTTTGCTCATCTTATTGGCCGTGGCGCGACTGCTTCCGAAGAGGAAGAGGACAAAA
AGGCCAAAAAAGCGAAAGGC

Product: S49 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNLPHLAQRLFNTPLALHPSKAEVIMASVMDRFGISKIESSLAMDDDWYGYDDNRGRESRSDPGYDNVLGVAVIPICGTL
VQKLGSLRPYSGMTGYDGIRQAFLTAMEDPDITGICLDIDSPGGEVAGCFDLVDVIYGARGKKPIHAILTESAYSAAYAI
ASAADRISVPRTAGVGSVGVITMHLDWTQRIKDDGLKVTIITYGSRKAEGAPLRELSDEALAAIQQDINTMGELFVNTVA
RNRGISAKVIKSTQAACFMAADGVELGLADEVCPPDAAFRNLLEKTGA

Sequences:

>Translated_288_residues
MNLPHLAQRLFNTPLALHPSKAEVIMASVMDRFGISKIESSLAMDDDWYGYDDNRGRESRSDPGYDNVLGVAVIPICGTL
VQKLGSLRPYSGMTGYDGIRQAFLTAMEDPDITGICLDIDSPGGEVAGCFDLVDVIYGARGKKPIHAILTESAYSAAYAI
ASAADRISVPRTAGVGSVGVITMHLDWTQRIKDDGLKVTIITYGSRKAEGAPLRELSDEALAAIQQDINTMGELFVNTVA
RNRGISAKVIKSTQAACFMAADGVELGLADEVCPPDAAFRNLLEKTGA
>Mature_288_residues
MNLPHLAQRLFNTPLALHPSKAEVIMASVMDRFGISKIESSLAMDDDWYGYDDNRGRESRSDPGYDNVLGVAVIPICGTL
VQKLGSLRPYSGMTGYDGIRQAFLTAMEDPDITGICLDIDSPGGEVAGCFDLVDVIYGARGKKPIHAILTESAYSAAYAI
ASAADRISVPRTAGVGSVGVITMHLDWTQRIKDDGLKVTIITYGSRKAEGAPLRELSDEALAAIQQDINTMGELFVNTVA
RNRGISAKVIKSTQAACFMAADGVELGLADEVCPPDAAFRNLLEKTGA

Specific function: Multicopy Suppressor Of The Htra (Degp) Null Phenotype. It Is Possibly A Protease, Not Essential For Bacterial VIability. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 30773; Mature: 30773

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPHLAQRLFNTPLALHPSKAEVIMASVMDRFGISKIESSLAMDDDWYGYDDNRGRESR
CCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCC
SDPGYDNVLGVAVIPICGTLVQKLGSLRPYSGMTGYDGIRQAFLTAMEDPDITGICLDID
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEC
SPGGEVAGCFDLVDVIYGARGKKPIHAILTESAYSAAYAIASAADRISVPRTAGVGSVGV
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
ITMHLDWTQRIKDDGLKVTIITYGSRKAEGAPLRELSDEALAAIQQDINTMGELFVNTVA
EEEECCHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRGISAKVIKSTQAACFMAADGVELGLADEVCPPDAAFRNLLEKTGA
HCCCCCHHHHHHCHHEEEEECCCCEECCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNLPHLAQRLFNTPLALHPSKAEVIMASVMDRFGISKIESSLAMDDDWYGYDDNRGRESR
CCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCC
SDPGYDNVLGVAVIPICGTLVQKLGSLRPYSGMTGYDGIRQAFLTAMEDPDITGICLDID
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEC
SPGGEVAGCFDLVDVIYGARGKKPIHAILTESAYSAAYAIASAADRISVPRTAGVGSVGV
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
ITMHLDWTQRIKDDGLKVTIITYGSRKAEGAPLRELSDEALAAIQQDINTMGELFVNTVA
EEEECCHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRGISAKVIKSTQAACFMAADGVELGLADEVCPPDAAFRNLLEKTGA
HCCCCCHHHHHHCHHEEEEECCCCEECCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]