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The map label for this gene is torZ [H]

Identifier: 157161343

GI number: 157161343

Start: 1973749

End: 1976196

Strand: Reverse

Name: torZ [H]

Synonym: EcHS_A1967

Alternate gene names: 157161343

Gene position: 1976196-1973749 (Counterclockwise)

Preceding gene: 157161344

Following gene: 157161336

Centisome position: 42.56

GC content: 51.59

Gene sequence:

>2448_bases
TTGATCAGGGAGGAAGTTATGACATTAACAAGACGTGAATTTATTAAACACAGCGGTATTGCCGCTGGAGCGCTGGTGGT
GACATCGGCAGCACCGCTACCCGCATGGGCAGAAGAGAAGGGCGGTAAAATCCTCACCGCGGGACGCTGGGGAGCGATGA
ACGTAGAAGTGAAGGACGGCAAGATTGTTTCTTCGACAGGCGCGCTGGCGAAAACCATACCGAACTCCTTACAGTCTACG
GCGGCGGATCAGGTACACACCACGGCGCGTATTCAGCATCCGATGGTGAGAAAAAGCTATCTCGATAATCCACTGCAACC
GGCGAAAGGTCGAGGCGAAGATACCTATGTACAGGTGAGCTGGGAACAAGCATTAAAACTGATTCATGAGCAACACGATC
GTATTCGTAAAGCTAACGGACCATCGGCCATTTTTGCCGGATCTTACGGCTGGCGCTCTTCTGGCGTGTTGCATAAAGCG
CAAACCTTACTGCAACGTTATATGAACCTCGCGGGCGGTTATTCCGGGCATAGCGGCGATTATTCAACCGGGGCAGCACA
GGTGATCATGCCGCATGTGGTCGGTTCTGTAGAGGTGTATGAACAGCAGACCTCCTGGCCGCTGATTCTGGAAAACAGCC
AGGTTGTGGTGCTGTGGGGGATGAACCCGCTGAATACCTTAAAAATTGCCTGGAGCAGTACCGATGAGCAAGGGCTGGAA
TACTTCCATCAGCTGAAAAAATCTGGCAAACCAGTGATTGCCATTGATCCTATCCGCTCCGAAACCATTGAGTTCTTTGG
CGATAATGCCACCTGGATCGCGCCGAATATGGGCACCGACGTGGCACTGATGTTAGGGATTGCGCATACCCTGATGACAC
AAGGCAAACACGATAAAGTGTTCCTTGAAAAATACACCACCGGGTATCCGCAGTTTGAAGAATATCTGACAGGTAAGAGC
GATAATACTCCGAAGAGCGCGGCCTGGGCGGCGGAAATTACTGGCGTACCGGAAGCGCAGATAGTCAAACTCGCTGAACT
GATGGCGGCGAATCGCACAATGCTGATGGCAGGCTGGGGAATTCAGCGCCAGCAATATGGTGAACAGAAACACTGGATGC
TGGTGACGCTGGCGGCGATGTTAGGGCAGATTGGTACACCGGGCGGCGGTTTTGGTTTCTCTTATCATTACTCCAATGGT
GGCAACCCGACACGTGTTGGCGGCGTGCTGCCGGAAATGTCTGCGGCGATTGCCGGACAGGCCAGCGAGGCCGCTGATGA
TGGCGGAATGACGGCGATTCCTGTTGCCCGTATCGTCGATGCGCTGGAAAATCCTGGCGGCAAATATCAGCATAACGGTA
AAGAGCAAACGTATCCGAATATCAAAATGATCTGGTGGGCGGGTGGCGGTAACTTTACCCATCACCAGGATACTAATCGT
CTGATTAAAGCATGGCAGAAACCGGAGATGATCGTCGTTTCTGAATGCTACTGGACCGCAGCTGCTAAACATGCAGATAT
CGTATTACCGATCACCACATCGTTTGAGCGCAATGACTTGACGATGACCGGTGATTACAGCAACCAGCATATTGTGCCGA
TGAAGCAGGCTGTCGCTCCGCAATTTGAAGCGCGAAACGATTTTGATGTGTTTGCCGATCTTGCGGAATTACTGAAACCT
GGCGGAAAAGAGATCTATACCGAAGGTAAAGATGAAATGGCGTGGCTGAAATTTTTCTATGATGCCGCTCAGAAAGGTGC
CCGTGCGCAACGCGTGACTATGCCGATGTTTAATGCCTTCTGGCAGCAAAATAAACTGATCGAAATGCGCCGCAGCGAGA
AGAACGAACAGTACGTTCGTTATGGTGATTTCCGCGCCGATCCGGTGAAAAATGCGCTGGGTACGCCAAGCGGCAAAATT
GAGATTTACTCCAAAACGCTGGAAAAATTTGGCTATAAGGATTGCCCGGCACACCCAACCTGGCTTGCGCCTGATGAGTG
GAAGGGTACCGCCGACGAGAAGCAGTTGCAGCTTCTGACCGCACATCCGGCACACCGTTTACATAGTCAGCTTAACTATG
CGGAACTGCGTAAAAAATATGCGGTTGCAGATCGTGAACCAATCACTATTCACACCGAAGATGCTGCTCGCTTTGGTATT
GCGAATGGTGATCTGGTGCGTGTGTGGAACAAACGTGGTCAGATTCTGACAGGCGCGGTGGTGACTGACGGGATCAAAAA
AGGCGTGGTATGCGTGCATGAAGGTGCATGGCCAGATCTGGAAAATGGCTTGTGTAAAAACGGCAGTGCGAACGTGTTAA
CGGCGGATATCCCCAGCTCGCAGCTGGCAAATGCCTGTGCCGGTAACTCTGCGCTGGTGTATATCGAAAAATATACGGGC
AATGCGCCGAAGTTAACGGCGTTTGATCAGCCAGCTATTCAGGCATAA

Upstream 100 bases:

>100_bases
AATGGGGGCACGAACCAGCATGAGCGAAAACGAACTGGACATTTTAACGCGGTATTTCCAGTACAACGCCAAAGATATTA
CCGAGAAACAGTGATCCTCG

Downstream 100 bases:

>100_bases
GAAGTGAATAGCGCCCGGAAACGGGCGCTGAGGTTATGCAAACGTAAAGCTGCCTGATGCGCTATGCTTATCAGGCCTAC
ATAGTCCCTGCAATATATTG

Product: trimethylamine N-oxide reductase III, subunit TorZ

Products: NA

Alternate protein names: TMAO reductase 2; Trimethylamine oxidase 2 [H]

Number of amino acids: Translated: 815; Mature: 815

Protein sequence:

>815_residues
MIREEVMTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSSTGALAKTIPNSLQST
AADQVHTTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKA
QTLLQRYMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLE
YFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKS
DNTPKSAAWAAEITGVPEAQIVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNG
GNPTRVGGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNR
LIKAWQKPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKP
GGKEIYTEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKI
EIYSKTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGI
ANGDLVRVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTG
NAPKLTAFDQPAIQA

Sequences:

>Translated_815_residues
MIREEVMTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSSTGALAKTIPNSLQST
AADQVHTTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKA
QTLLQRYMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLE
YFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKS
DNTPKSAAWAAEITGVPEAQIVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNG
GNPTRVGGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNR
LIKAWQKPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKP
GGKEIYTEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKI
EIYSKTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGI
ANGDLVRVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTG
NAPKLTAFDQPAIQA
>Mature_815_residues
MIREEVMTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSSTGALAKTIPNSLQST
AADQVHTTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKA
QTLLQRYMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLE
YFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKS
DNTPKSAAWAAEITGVPEAQIVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNG
GNPTRVGGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNR
LIKAWQKPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKP
GGKEIYTEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKI
EIYSKTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGI
ANGDLVRVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTG
NAPKLTAFDQPAIQA

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. Can also reduce other N- and S-oxide compounds such as 4-methylmorpholine-N-oxide and biotin sulfoxide (BSO), but with a lower catalytic

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=809, Percent_Identity=99.2583436341162, Blast_Score=1674, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=773, Percent_Identity=63.9068564036222, Blast_Score=1065, Evalue=0.0,
Organism=Escherichia coli, GI1787231, Length=786, Percent_Identity=45.5470737913486, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=753, Percent_Identity=31.0756972111554, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1787870, Length=853, Percent_Identity=28.9566236811254, Blast_Score=272, Evalue=5e-74,
Organism=Escherichia coli, GI171474008, Length=840, Percent_Identity=28.5714285714286, Blast_Score=239, Evalue=8e-64,
Organism=Escherichia coli, GI3868721, Length=719, Percent_Identity=22.8094575799722, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 89647; Mature: 89647

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREEVMTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDG
CCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCEEEEECCCCEEEEEECCC
KIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCEEEEE
WEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQRYMNLAGGYSGHSGD
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
YSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLE
CCCCHHHHHHHHHHCCEEEEECCCCCCEEEECCCEEEEECCCCCCEEEEEECCCCHHHHH
YFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKV
HHHHHHHCCCCEEEECCCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCEE
FLEKYTTGYPQFEEYLTGKSDNTPKSAAWAAEITGVPEAQIVKLAELMAANRTMLMAGWG
EEEHHCCCCCCHHHHHCCCCCCCCCCHHEEEHCCCCCHHHHHHHHHHHHCCCEEEEECCC
IQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNGGNPTRVGGVLPEMSAAIAGQ
CCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCC
ASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNR
CCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHH
LIKAWQKPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAP
HHHHHCCCCEEEEECCHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCEECCHHHHHCC
QFEARNDFDVFADLAELLKPGGKEIYTEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAF
CCCCCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
WQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKIEIYSKTLEKFGYKDCPAHPT
HHCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCC
WLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGI
CCCCCCCCCCCCHHHEEEEECCCHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCHHHCCC
ANGDLVRVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSS
CCCCEEEEECCCCCEEEEHHHHCCHHCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCHH
QLANACAGNSALVYIEKYTGNAPKLTAFDQPAIQA
HHHHHHCCCCEEEEEEECCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MIREEVMTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDG
CCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCEEEEECCCCEEEEEECCC
KIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCEEEEE
WEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQRYMNLAGGYSGHSGD
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
YSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLE
CCCCHHHHHHHHHHCCEEEEECCCCCCEEEECCCEEEEECCCCCCEEEEEECCCCHHHHH
YFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKV
HHHHHHHCCCCEEEECCCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCEE
FLEKYTTGYPQFEEYLTGKSDNTPKSAAWAAEITGVPEAQIVKLAELMAANRTMLMAGWG
EEEHHCCCCCCHHHHHCCCCCCCCCCHHEEEHCCCCCHHHHHHHHHHHHCCCEEEEECCC
IQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNGGNPTRVGGVLPEMSAAIAGQ
CCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCC
ASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNR
CCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHH
LIKAWQKPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAP
HHHHHCCCCEEEEECCHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCEECCHHHHHCC
QFEARNDFDVFADLAELLKPGGKEIYTEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAF
CCCCCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
WQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKIEIYSKTLEKFGYKDCPAHPT
HHCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCC
WLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGI
CCCCCCCCCCCCHHHEEEEECCCHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCHHHCCC
ANGDLVRVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSS
CCCCEEEEECCCCCEEEEHHHHCCHHCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCHH
QLANACAGNSALVYIEKYTGNAPKLTAFDQPAIQA
HHHHHHCCCCEEEEEEECCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]