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The map label for this gene is yeaN

Identifier: 157161253

GI number: 157161253

Start: 1893650

End: 1894831

Strand: Direct

Name: yeaN

Synonym: EcHS_A1877

Alternate gene names: 157161253

Gene position: 1893650-1894831 (Clockwise)

Preceding gene: 157161251

Following gene: 157161254

Centisome position: 40.78

GC content: 52.88

Gene sequence:

>1182_bases
ATGACCTGTTCAACTTCATTAAGCGGCAAAAACAGGATTGTCCTTATCGCTGGCATTCTGATGATTGCCACAACATTACG
CGTCACCTTCACCGGCGCAGCACCGTTACTCGATACGATTCGTTCCGCTTACTCGCTGACGACAGCGCAAACCGGCTTAT
TGACCACCCTGCCATTATTGGCCTTTGCGCTAATCTCACCTTTGGCCGCCCCGGTAGCGCGACGTTTTGGTATGGAACGT
AGCCTGTTTGCCGCGTTACTTTTGATCTGTGCTGGTATCGCAATTCGCTCTCTCCCTTCGCCTTACTTATTATTTGGCGG
TACAGCGGTCATTGGCGGTGGGATTGCATTAGGCAATGTCTTACTGCCAGGATTAATTAAACGCGATTTCCCTCATTCCG
TCGCCAGACTTACCGGCGCATATTCCCTGACAATGGGAGCTGCGGCGGCACTTGGATCGGCTATGGTCGTGCCGCTGGCT
TTGAACGGTTTTGGCTGGCAAGGCGCGTTGCTCATGCTGATGTGTTTTCCTCTGCTGGCTCTTTTTTTATGGCTGCCACA
GTGGCGAAGCCAACAACATGCAAATTTGAGTACCTCGCGCGCCTTACATACTCGGGGTATCTGGCGTTCGCCGCTTGCCT
GGCAGGTCACATTGTTTCTTGGGATCAACTCACTGGTCTATTACGTGATTATTGGCTGGCTTCCGGCGATCCTCATCAGT
CACGGCTATAGCGAAGCACAGGCGGGTTCACTGCATGGTTTGCTGCAACTAGCCACAGCAGCTCCCGGTTTGCTGATCCC
TCTTTTCTTACATCATGTGAAAGATCAGCGTGGTATTGCAGCGTTCGTTGCCTTGATGTGCGCAGTGGGCGCTGTTGGGC
TCTGCTTTATGCCAGCGCACGCGATCACCTGGACTCTGCTTTTCGGTTTTGGTTCCGGCGCAACAATGATACTGGGGTTG
ACGTTCATTGGTCTTCGGGCAAGTTCTGCGCATCAGGCGGCGGCACTCTCGGGGATGGCACAATCCGTCGGGTATTTGTT
GGCAGCCTGTGGGCCGCCGCTGATGGGTAAAATACACGATGCTAACGGTAACTGGTCTGTACCACTTATGGGTGTTGCCA
TACTTTCACTACTGATGGCGATTTTCGGACTTTGCGCCGGGAGAGACAAAGAAATTCGCTAA

Upstream 100 bases:

>100_bases
TCATTTTGTCCGAATTTAGCGATAATTTGTCATTTTAGCTTGATTCAACATAACAATAAAAACGGTAAGGTACAGCCTCG
TTTGTAACAATGAGAAGCAT

Downstream 100 bases:

>100_bases
TATCCGGTGCTATAGTGACGTAACAAATCATGCGTGAAAGGGAGAACAAACACGATGAATATTCAGTGCAAACGCGTTTA
TGATCCGGCTGAACAGAGCG

Product: inner membrane transport protein yeaN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMER
SLFAALLLICAGIAIRSLPSPYLLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
LNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILIS
HGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQRGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGL
TFIGLRASSAHQAAALSGMAQSVGYLLAACGPPLMGKIHDANGNWSVPLMGVAILSLLMAIFGLCAGRDKEIR

Sequences:

>Translated_393_residues
MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMER
SLFAALLLICAGIAIRSLPSPYLLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
LNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILIS
HGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQRGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGL
TFIGLRASSAHQAAALSGMAQSVGYLLAACGPPLMGKIHDANGNWSVPLMGVAILSLLMAIFGLCAGRDKEIR
>Mature_392_residues
TCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERS
LFAALLLICAGIAIRSLPSPYLLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLAL
NGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILISH
GYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQRGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLT
FIGLRASSAHQAAALSGMAQSVGYLLAACGPPLMGKIHDANGNWSVPLMGVAILSLLMAIFGLCAGRDKEIR

Specific function: Unknown

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family

Homologues:

Organism=Escherichia coli, GI1788092, Length=393, Percent_Identity=100, Blast_Score=766, Evalue=0.0,
Organism=Escherichia coli, GI1786536, Length=349, Percent_Identity=26.647564469914, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEAN_ECOLI (P76242)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   G64939
- RefSeq:   AP_002410.1
- RefSeq:   NP_416305.1
- ProteinModelPortal:   P76242
- SMR:   P76242
- STRING:   P76242
- EnsemblBacteria:   EBESCT00000001648
- EnsemblBacteria:   EBESCT00000014767
- GeneID:   946309
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1780
- KEGG:   eco:b1791
- EchoBASE:   EB3273
- EcoGene:   EG13500
- eggNOG:   COG2807
- GeneTree:   EBGT00050000008822
- HOGENOM:   HBG696945
- OMA:   SILIGRG
- ProtClustDB:   CLSK880204
- BioCyc:   EcoCyc:B1791-MONOMER
- Genevestigator:   P76242
- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- TIGRFAMs:   TIGR00896

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 41209; Mature: 41078

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1536fb54)-; HASH(0x152912a4)-; HASH(0xeb7b8c8)-; HASH(0x14e5c8f0)-; HASH(0x14c9bf18)-; HASH(0x14c87c68)-; HASH(0x15407c44)-; HASH(0x1578f928)-; HASH(0x153e9460)-; HASH(0x153cc550)-; HASH(0x15272eb0)-; HASH(0x15407c5c)-;

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTTAQTGLLTTLPLL
CCCCCCCCCCCCEEHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPYLLFGGTAVIGGGIALGNV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCHHHHHHH
LLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLALNGFGWQGALLMLMCFPLLA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEHEECCCCHHHHHHHHHHHHHHH
LFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILIS
HHHHCHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQRGIAAFVALMCAVGAVGLCFMPAH
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AITWTLLFGFGSGATMILGLTFIGLRASSAHQAAALSGMAQSVGYLLAACGPPLMGKIHD
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
ANGNWSVPLMGVAILSLLMAIFGLCAGRDKEIR
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure 
TCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTTAQTGLLTTLPLL
CCCCCCCCCCCEEHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPYLLFGGTAVIGGGIALGNV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCHHHHHHH
LLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLALNGFGWQGALLMLMCFPLLA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEHEECCCCHHHHHHHHHHHHHHH
LFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILIS
HHHHCHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQRGIAAFVALMCAVGAVGLCFMPAH
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AITWTLLFGFGSGATMILGLTFIGLRASSAHQAAALSGMAQSVGYLLAACGPPLMGKIHD
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
ANGNWSVPLMGVAILSLLMAIFGLCAGRDKEIR
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503