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The map label for this gene is msrB [H]

Identifier: 157161239

GI number: 157161239

Start: 1879993

End: 1880406

Strand: Reverse

Name: msrB [H]

Synonym: EcHS_A1863

Alternate gene names: 157161239

Gene position: 1880406-1879993 (Counterclockwise)

Preceding gene: 157161242

Following gene: 157161238

Centisome position: 40.5

GC content: 47.34

Gene sequence:

>414_bases
ATGGCTAATAAACCTTCGGCAGAAGAACTGAAAAAAAATTTGTCCGAGATGCAGTTTTACGTGACGCAGAATCATGGGAC
AGAACCGCCATTTACGGGTCGTTTACTGCATAACAAGCGTGACGGCGTATATCACTGTTTGATCTGCGATGCCCCGCTGT
TTCATTCCGAAACCAAGTATGATTCCGGCTGTGGCTGGCCCAGTTTCTACGAACCGGTGAGTGAAGAATCCATTCGTTAT
ATCAAAGACTTGTCACATGGAATGCAGCGCATAGAAATTCGTTGCGGTAACTGTGATGCTCATCTGGGGCATGTCTTTCC
CGACGGGCCGCAACCAACAGGCGAACGTTATTGTGTTAACTCTGCTTCTTTACGCTTCACTGATGGCGAAAACGGCGAAG
AAATCAACGGTTGA

Upstream 100 bases:

>100_bases
CGTCGAGATCAAGTTTAGGACAAAATTTTGCCAGTTGGTGTTAATGTTTTGTTAGAATCAGTCACGTAATGTGAGCACGA
TTAAAGTGAGATGTGAGCAA

Downstream 100 bases:

>100_bases
AAAAACGATTCAGCAACTTATTCCACAGGAGCGGAAAAATTATGAATCTTGATGACATTATCAACAGCATGACGCCTGAG
GTATACCAGCGTTTGTCGAC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSETKYDSGCGWPSFYEPVSEESIRY
IKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING

Sequences:

>Translated_137_residues
MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSETKYDSGCGWPSFYEPVSEESIRY
IKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
>Mature_136_residues
ANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSETKYDSGCGWPSFYEPVSEESIRYI
KDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=132, Percent_Identity=50.7575757575758, Blast_Score=158, Evalue=2e-39,
Organism=Homo sapiens, GI301336162, Length=132, Percent_Identity=50.7575757575758, Blast_Score=158, Evalue=2e-39,
Organism=Homo sapiens, GI73089054, Length=132, Percent_Identity=50.7575757575758, Blast_Score=158, Evalue=2e-39,
Organism=Homo sapiens, GI37620216, Length=132, Percent_Identity=50.7575757575758, Blast_Score=157, Evalue=2e-39,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=53.90625, Blast_Score=139, Evalue=9e-34,
Organism=Escherichia coli, GI1788077, Length=137, Percent_Identity=99.2700729927007, Blast_Score=289, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI17553450, Length=120, Percent_Identity=49.1666666666667, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=120, Percent_Identity=49.1666666666667, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319816, Length=132, Percent_Identity=43.1818181818182, Blast_Score=108, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24645799, Length=124, Percent_Identity=50, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI45553335, Length=124, Percent_Identity=50, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21356369, Length=124, Percent_Identity=50, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI221378664, Length=121, Percent_Identity=51.2396694214876, Blast_Score=132, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24645801, Length=135, Percent_Identity=45.9259259259259, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645804, Length=135, Percent_Identity=45.9259259259259, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221378662, Length=128, Percent_Identity=48.4375, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15452; Mature: 15321

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSETKY
CCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCC
DSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVN
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
SASLRFTDGENGEEING
CCEEEECCCCCCCCCCC
>Mature Secondary Structure 
ANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSETKY
CCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCC
DSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVN
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
SASLRFTDGENGEEING
CCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA