Click here to switch to the map view.

The map label for this gene is ydjG [H]

Identifier: 157161233

GI number: 157161233

Start: 1873074

End: 1874054

Strand: Reverse

Name: ydjG [H]

Synonym: EcHS_A1855

Alternate gene names: 157161233

Gene position: 1874054-1873074 (Counterclockwise)

Preceding gene: 157161234

Following gene: 157161232

Centisome position: 40.36

GC content: 47.91

Gene sequence:

>981_bases
ATGAAAAAGATACCTTTAGGCACAACGGATATTACGCTTTCGCGAATGGGGTTGGGGACATGGGCCATTGGCGGCGGTCC
TGCATGGAATGGCGATCTCGATCGGCAAATATGTATTGATACGATTCTTGAAGCCCATCGTTGCGGCATTAATCTGATTG
ATACTGCACCAGGATATAACTTTGGCAATAGTGAAGTTATCGTCGGTCAGGCGTTAAAAAAACTGCCCCGTGAACAGGTT
GTAGTAGAAACCAAATGCGGCATTGTCTGGGAACGAAAAGGAAGTTTATTCAACAAAGTTGGCGATCGGCAGTTGTATAA
AAACCTTTCCCCGGAATCTATCCGCGAAGAGGTAGAAGCCAGCTTGCAACGTCTGGGTATTGATTACATCGATATCTACA
TGACGCACTGGCAGTCGGTGCCGCCATTTTATACGCCGATCGCTGAAACTGTCGCAGTGCTTAATGAGTTAAAGGCTGAA
GGGAAAATTCGCGCGATAGGCGCTGCTAACGTCGATGCTGACCATATCCGCGAGTATCTGCAATATGGTGAACTGGATAT
TATTCAGGCGAAATACAGTATCCTCGACCGGGCAATGGAAAACGAACTGCTGCCGCTATGTCGTGATAATGGCATTGTGG
TTCAGGTTTATTCCCCGCTAGAGCAGGGATTGTTGACCGGCACCATCACTCGTGATTACGTTCCGGGTGGCGCTCGGGCA
AATAAAGTCTGGTTCCAGCGTGAAAACATGCTGAAAGTGATTGATATGCTTGAACAGTGGCAGCCACTTTGTGCTCGTTA
TCAGTGCACAATTCCCACTCTGGCACTGGCGTGGATATTAAAACAGAGTGATTTAATCTCCATTCTTAGTGGGGCTACTG
CACCGGAACAGGTACGCGAAAATGTCGCGGCACTGATTATCAACTTATCGGATGCAGACGCAACATTGATGAGGGAAATG
GCAGAGGCCCTGGAGCGTTAA

Upstream 100 bases:

>100_bases
GGCGGCTATCTCGGTTCTAAGCGTCGGTGCCACCACCGGCGTAAAAAACAGAAAGCTGGTCGAACAATTGCTGGAAGAAT
ACGAAGGATAATGAAGGCAA

Downstream 100 bases:

>100_bases
ATACTCAACACGATTCACCTCTGTTTCTGTGAAAACTGTGATGAAAATCTGTGATTCAAACAGGTTGTTTTGAAAGTAAA
CATCGGTTATGCGATAATCG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQV
VVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVEASLQRLGIDYIDIYMTHWQSVPPFYTPIAETVAVLNELKAE
GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALIINLSDADATLMREM
AEALER

Sequences:

>Translated_326_residues
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQV
VVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVEASLQRLGIDYIDIYMTHWQSVPPFYTPIAETVAVLNELKAE
GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALIINLSDADATLMREM
AEALER
>Mature_326_residues
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQV
VVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVEASLQRLGIDYIDIYMTHWQSVPPFYTPIAETVAVLNELKAE
GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALIINLSDADATLMREM
AEALER

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=321, Percent_Identity=30.5295950155763, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI27436966, Length=318, Percent_Identity=30.188679245283, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436962, Length=318, Percent_Identity=30.188679245283, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436969, Length=335, Percent_Identity=28.0597014925373, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4504825, Length=335, Percent_Identity=28.0597014925373, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=28.1345565749235, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI223718702, Length=283, Percent_Identity=27.5618374558304, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI41327764, Length=281, Percent_Identity=26.3345195729537, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI41152114, Length=282, Percent_Identity=26.5957446808511, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1788070, Length=326, Percent_Identity=98.7730061349693, Blast_Score=661, Evalue=0.0,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=33.9506172839506, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1789199, Length=340, Percent_Identity=29.1176470588235, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788081, Length=313, Percent_Identity=28.1150159744409, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789375, Length=317, Percent_Identity=26.4984227129338, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787674, Length=309, Percent_Identity=25.5663430420712, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17564128, Length=335, Percent_Identity=25.0746268656716, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI212645785, Length=169, Percent_Identity=34.3195266272189, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17552492, Length=315, Percent_Identity=25.0793650793651, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538386, Length=309, Percent_Identity=25.8899676375405, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=339, Percent_Identity=24.7787610619469, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=331, Percent_Identity=24.4712990936556, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319958, Length=293, Percent_Identity=21.8430034129693, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646159, Length=320, Percent_Identity=29.375, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24646155, Length=323, Percent_Identity=27.8637770897833, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36386; Mature: 36386

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYN
CCCCCCCCCCEEHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCC
FGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVEA
CCCCCCHHHHHHHHCCHHHEEEEECCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SLQRLGIDYIDIYMTHWQSVPPFYTPIAETVAVLNELKAEGKIRAIGAANVDADHIREYL
HHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
QYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
HHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHCCCEEECCCCCCCCCCCCC
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
NVAALIINLSDADATLMREMAEALER
HHHEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYN
CCCCCCCCCCEEHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCC
FGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVEA
CCCCCCHHHHHHHHCCHHHEEEEECCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SLQRLGIDYIDIYMTHWQSVPPFYTPIAETVAVLNELKAEGKIRAIGAANVDADHIREYL
HHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
QYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
HHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHCCCEEECCCCCCCCCCCCC
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
NVAALIINLSDADATLMREMAEALER
HHHEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]