Click here to switch to the map view.

The map label for this gene is mliC

Identifier: 157161101

GI number: 157161101

Start: 1740019

End: 1740342

Strand: Reverse

Name: mliC

Synonym: EcHS_A1715

Alternate gene names: 157161101

Gene position: 1740342-1740019 (Counterclockwise)

Preceding gene: 157161102

Following gene: 157161100

Centisome position: 37.48

GC content: 45.99

Gene sequence:

>324_bases
ATGAAAAAACTGTTAATTATCATTTTGCCGGTCCTTCTCTCCGGCTGTAGCGCCTTTAATCAGCTGGTTGAGCGCATGCA
AACCGATACGCTGGAATACCAGTGTGATGAAAAACCGTTGACGGTCAAACTGAATAATCCGCGCCAGGAGGTCAGTTTTG
TTTACGATAATCAACTACTGCATCTCAAACAGGGCATTTCAGCCTCTGGCGCGCGTTACACTGACGGAATCTATGTTTTC
TGGTCGAAAGGCGATGAAGCGACTGTCTATAAACGCGACCGCATCGTCTTGAATAACTGTCAGTTACAAAATCCACAGCG
TTGA

Upstream 100 bases:

>100_bases
CAGAGTTAACTGAATTTTTCTTACCGCGTCTGCCGTTACACTTGGAACGTTAGGGAGGGCGTATTGCCCTCCAGACCAGG
AAAGTCTTCGGGATATGACT

Downstream 100 bases:

>100_bases
GATTTTTCCAGGGGCGGCGCACAATAGCGTCACCCACTGACAATCCGTAAAGAAAACCATGTCTGATAACGACGAATTGC
AGCAAATCGCGCATCTGCGC

Product: lysozyme inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTVKLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVF
WSKGDEATVYKRDRIVLNNCQLQNPQR

Sequences:

>Translated_107_residues
MKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTVKLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVF
WSKGDEATVYKRDRIVLNNCQLQNPQR
>Mature_107_residues
MKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTVKLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVF
WSKGDEATVYKRDRIVLNNCQLQNPQR

Specific function: Specifically inhibits C-type lysozymes

COG id: COG3895

COG function: function code R; Predicted periplasmic protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor. Note=Anchored to the periplasmic side

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mliC family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI87081949, Length=107, Percent_Identity=100, Blast_Score=224, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MLIC_ECOLI (P28224)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   M92351
- PIR:   A43261
- RefSeq:   AP_002261.1
- RefSeq:   NP_416156.4
- PDB:   2F09
- PDBsum:   2F09
- ProteinModelPortal:   P28224
- SMR:   P28224
- DIP:   DIP-11726N
- STRING:   P28224
- EnsemblBacteria:   EBESCT00000003952
- EnsemblBacteria:   EBESCT00000016260
- GeneID:   946811
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1631
- KEGG:   eco:b1639
- EchoBASE:   EB1451
- EcoGene:   EG11488
- eggNOG:   COG3895
- GeneTree:   EBGT00050000010880
- HOGENOM:   HBG437057
- OMA:   LAGCSYY
- ProtClustDB:   PRK11372
- BioCyc:   EcoCyc:EG11488-MONOMER
- Genevestigator:   P28224
- InterPro:   IPR018660

Pfam domain/function: PF09864 DUF2091

EC number: NA

Molecular weight: Translated: 12335; Mature: 12335

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTVKLNNPRQEVSFVYDNQLL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHEEEEECCCEE
HLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNCQLQNPQR
EECCCCCCCCCEECCCEEEEECCCCCEEEEECCEEEEECCCCCCCCC
>Mature Secondary Structure
MKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTVKLNNPRQEVSFVYDNQLL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHEEEEECCCEE
HLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNCQLQNPQR
EECCCCCCCCCEECCCEEEEECCCCCEEEEECCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1356963