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The map label for this gene is frmR

Identifier: 157159874

GI number: 157159874

Start: 444889

End: 445164

Strand: Reverse

Name: frmR

Synonym: EcHS_A0422

Alternate gene names: 157159874

Gene position: 445164-444889 (Counterclockwise)

Preceding gene: 157159875

Following gene: 157159873

Centisome position: 9.59

GC content: 52.9

Gene sequence:

>276_bases
ATGCCCAGTACTCCGGAAGAGAAGAAAAAGGTCCTTACTCGAGTTCGTCGTATTCGAGGGCAGATTGATGCTCTGGAACG
GTCGCTGGAGGGTGATGCCGAATGCCGTGCCATACTCCAACAGATCGCTGCCGTTCGGGGCGCGGCTAATGGGCTGATGG
CAGAAGTGCTTGAAAGCCATATCCGGGAAACGTTTGACCGAAATGACTGCTACAGCCGCGAAGTCAGCCAATCCGTTGAC
GACACTATTGAACTGGTTCGAGCCTATCTTAAATAG

Upstream 100 bases:

>100_bases
GATAAATTTTATTCTCCAGTGTTATATACTATAGGGGGGTATGCATTGACATATAGCATACCCCCCTATAGTATATTGCG
TGCAGATAATGAGGTGCGAA

Downstream 100 bases:

>100_bases
CTGAATCTATTACCATATTGAGGAAGAGCGAGAGATGAAATCACGTGCTGCCGTTGCATTTGCTCCCGGTAAACCGCTGG
AAATCGTTGAAATTGACGTT

Product: regulator protein FrmR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVD
DTIELVRAYLK

Sequences:

>Translated_91_residues
MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVD
DTIELVRAYLK
>Mature_90_residues
PSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDD
TIELVRAYLK

Specific function: Repressor of the frmRAB operon

COG id: COG1937

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frmR/rcnR family

Homologues:

Organism=Escherichia coli, GI87081725, Length=91, Percent_Identity=100, Blast_Score=185, Evalue=5e-49,
Organism=Escherichia coli, GI1788422, Length=92, Percent_Identity=40.2173913043478, Blast_Score=69, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRMR_ECO24 (A7ZIA5)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461534.1
- ProteinModelPortal:   A7ZIA5
- SMR:   A7ZIA5
- STRING:   A7ZIA5
- EnsemblBacteria:   EBESCT00000020012
- GeneID:   5587587
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0382
- eggNOG:   COG1937
- GeneTree:   EBGT00050000008906
- HOGENOM:   HBG661347
- OMA:   RMAEVGH
- ProtClustDB:   PRK11352
- BioCyc:   ECOL331111:ECE24377A_0382-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR003735

Pfam domain/function: PF02583 DUF156

EC number: NA

Molecular weight: Translated: 10318; Mature: 10187

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRETFDRNDCYSREVSQSVDDTIELVRAYLK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRETFDRNDCYSREVSQSVDDTIELVRAYLK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA