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The map label for this gene is fhiA [H]

Identifier: 157159713

GI number: 157159713

Start: 277808

End: 279547

Strand: Reverse

Name: fhiA [H]

Synonym: EcHS_A0259

Alternate gene names: 157159713

Gene position: 279547-277808 (Counterclockwise)

Preceding gene: 157159719

Following gene: 157159712

Centisome position: 6.02

GC content: 57.36

Gene sequence:

>1740_bases
ATGCTTTCACGCTCGGATTTACTGACGCTGTTGACAATCAACTTTATTGTCGTCACCAAAGGGGCCGAGCGTATCTCCGA
GGTTTCTGCCCGCTTTACCCTGGACGCGATGCCCGGTAAGCAGATGGCGATTGACGCCGATCTTAATGCCGGGTTGATCA
ATCAGGCGCAGGCACAAACCCGACGTAAAGATGTTGCCAGCGAGGCCGATTTCTACGGCGCGATGGACGGGGCATCGAAA
TTTGTGCGCGGGGATGCTATCGCCGGGATGATGATTCTGGCGATCAACCTGATCGGCGGCGTCTATATCGGGATCTTCAA
ATACAACCTGAGCGCCGACGCCGCCTTCCAGCAGTATGTGCTGATGACCATCGGCGACGGGCTGGTGGCGCAAATCCCTT
CCCTGCTACTCTCCACCGCGGCGGCGATTATCGTCACCCGCGTCAGCGACAACGGCGATATCGCCCATGACGTGCGTAAC
CAGTTGCTGGCAAGCCCATCGGTGCTCTACACCGCTACCGGAATTATGTTCGTACTGGCGGTAGTGCCGGGAATGCCACA
TCTGCCGTTTTTGCTGTTCAGCGCCCTGCTTGGCTTTACCGGCTGGCGGATGAGCAAACGCCCGCAGGCGGCGGAAGCGG
AAGAGAAAAGTCTCGAAACGCTGACCCGCACCATCACCGAAACCAGCGAGCAACAGGTCAGTTGGGAAACCATTCCGCTG
ATCGAGCCCATCAGCTTAAGCCTCGGCTACAAGCTGGTGGCGCTGGTGGACAAAGCCCAGGGCAACCCGCTCACCCAGCG
TATTCGCGGCGTGCGACAGGTGATATCCGACGGCAACGGCGTGCTGCTGCCGGAGATCCGCATTCGGGAAAACTTCCGCC
TTAAGCCCAGCCAGTACGCTATTTTCATCAACGGCATTAAGGCTGATGAAGCGGATATTCCGGCGGATAAACTGATGGCG
CTGCCCTCCAGCGAAACCTACGGCGAGATAGACGGCGTGCTGGGGAACGACCCGGCGTACGGGATGCCGGTGACCTGGAT
CCAGCCTGCGCAGAAAGCGAAGGCGCTGAATATGGGGTATCAGGTGATCGACAGCGCCAGCGTGATTGCTACCCATGTAA
ATAAGATTGTGCGCAGCTATATTCCTGATTTATTTAACTATGACGATATTACGCAGTTGCATAACCGTTTGGCGTCGATG
GCACCGCGCCTGGCGGAGGATTTAAGCGCGGTGCTCAATTACAGCCAGTTGCTGAAAGTGTACCGGGCGCTGCTGACCGA
AGGCGTTTCCCTGCGCGATATCGTCACCATCGCCACCGTGCTGGTCGCCAGTAGCGCGGTGACCAAAGATCATATTCTGC
TGGCAGCCGATGTGCGCCTGGCGCTGCGGCGCAGCATTACCCATCCGTTCGTTCGCAAGCAGGAGCTGACGGTGTATACC
CTGAATAATGAGCTGGAAAATCTGCTGACTAACCTAGTGAATCAGGCGCAACAGGGCGGTAAAGTGATGCTCGACAGCGT
GCCAGTGGACCCGAATATGCTCAACCAGTTCCAGAGTACGATGCCACAGGTGAAAGAGCAGATGAAAACGGCGGGGAAAG
ACCCGGTGCTGCTGGTGCCACCGCAGCTGCGCCCTTTGCTGGCGCGTTATGCAAGGTTGTTTGCGCCGGGGCTGCATGTG
CTGTCGTATAACGAAGTGCCGGATGAGCTGGAGTTGAAGATTATGGGGGCGTTGAGTTGA

Upstream 100 bases:

>100_bases
CGCCACGGTGGCAGGTTTTGGCGGATGAGACGGGCTGATTTTATTTAACGGCGACAGCCCACCACCGTTAAAAATCGACT
GCCCGTGCAGCGCGGCGATA

Downstream 100 bases:

>100_bases
TGGGGGATTCTTTTCCATGCTTTGCAGCACCTGACACCATTAATTGACGTCACACTGCAAAGAGACTACGATGACACCAT
ACAATGACGTCATGGATTGA

Product: FHIPEP family type III secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASK
FVRGDAIAGMMILAINLIGGVYIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRN
QLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKRPQAAEAEEKSLETLTRTITETSEQQVSWETIPL
IEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMA
LPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQLHNRLASM
APRLAEDLSAVLNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVTKDHILLAADVRLALRRSITHPFVRKQELTVYT
LNNELENLLTNLVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKTAGKDPVLLVPPQLRPLLARYARLFAPGLHV
LSYNEVPDELELKIMGALS

Sequences:

>Translated_579_residues
MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASK
FVRGDAIAGMMILAINLIGGVYIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRN
QLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKRPQAAEAEEKSLETLTRTITETSEQQVSWETIPL
IEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMA
LPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQLHNRLASM
APRLAEDLSAVLNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVTKDHILLAADVRLALRRSITHPFVRKQELTVYT
LNNELENLLTNLVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKTAGKDPVLLVPPQLRPLLARYARLFAPGLHV
LSYNEVPDELELKIMGALS
>Mature_579_residues
MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASK
FVRGDAIAGMMILAINLIGGVYIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRN
QLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKRPQAAEAEEKSLETLTRTITETSEQQVSWETIPL
IEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMA
LPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQLHNRLASM
APRLAEDLSAVLNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVTKDHILLAADVRLALRRSITHPFVRKQELTVYT
LNNELENLLTNLVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKTAGKDPVLLVPPQLRPLLARYARLFAPGLHV
LSYNEVPDELELKIMGALS

Specific function: Not Known. [C]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=564, Percent_Identity=41.3120567375887, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 63280; Mature: 63280

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQT
CCCHHHHHHHHEEEEEEEECCHHHHHHHHHHEEEECCCCCCEEEECCCCCCHHHHHHHHH
RRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVYIGIFKYNLSADAAFQQYV
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHH
LMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRNQLLASPSVLYTATGIMFVLA
HHHCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVPGMPHLPFLLFSALLGFTGWRMSKRPQAAEAEEKSLETLTRTITETSEQQVSWETIPL
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCC
IEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYA
CCCCHHHCCCEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCEEECCEEECCCCCCCCCCEE
IFINGIKADEADIPADKLMALPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGY
EEEECCCCCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHCCH
QVIDSASVIATHVNKIVRSYIPDLFNYDDITQLHNRLASMAPRLAEDLSAVLNYSQLLKV
HHHCCHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
YRALLTEGVSLRDIVTIATVLVASSAVTKDHILLAADVRLALRRSITHPFVRKQELTVYT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCHHCCCCEEEEE
LNNELENLLTNLVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKTAGKDPVLLVP
ECHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PQLRPLLARYARLFAPGLHVLSYNEVPDELELKIMGALS
CCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCC
>Mature Secondary Structure
MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQT
CCCHHHHHHHHEEEEEEEECCHHHHHHHHHHEEEECCCCCCEEEECCCCCCHHHHHHHHH
RRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVYIGIFKYNLSADAAFQQYV
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHH
LMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRNQLLASPSVLYTATGIMFVLA
HHHCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVPGMPHLPFLLFSALLGFTGWRMSKRPQAAEAEEKSLETLTRTITETSEQQVSWETIPL
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCC
IEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYA
CCCCHHHCCCEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCEEECCEEECCCCCCCCCCEE
IFINGIKADEADIPADKLMALPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGY
EEEECCCCCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHCCH
QVIDSASVIATHVNKIVRSYIPDLFNYDDITQLHNRLASMAPRLAEDLSAVLNYSQLLKV
HHHCCHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
YRALLTEGVSLRDIVTIATVLVASSAVTKDHILLAADVRLALRRSITHPFVRKQELTVYT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCHHCCCCEEEEE
LNNELENLLTNLVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKTAGKDPVLLVP
ECHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PQLRPLLARYARLFAPGLHVLSYNEVPDELELKIMGALS
CCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7596361; 9278503 [H]