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The map label for this gene is yaeB

Identifier: 157159662

GI number: 157159662

Start: 218278

End: 218985

Strand: Reverse

Name: yaeB

Synonym: EcHS_A0199

Alternate gene names: 157159662

Gene position: 218985-218278 (Counterclockwise)

Preceding gene: 157159663

Following gene: 157159661

Centisome position: 4.72

GC content: 54.94

Gene sequence:

>708_bases
ATGAGCAGTTTCCAGTTCGAGCAAATAGGCGTTATTCGCTCGCCCTATAAAGAAAAATTCGCCGTTCCGCGCCAGCCAGG
TCTGGTAAAAAGCGCCAACGGCGAACTGCATCTCATTGCTCCCTACAACCAGGCCGACGCCGTTCGCGGCCTGGAAGCGT
TCAGCCATTTATGGATCCTTTTCGTCTTTCATCAAACGATGGAAGGCGGCTGGCGTCCGACTGTGCGTCCACCGCGCCTC
GGCGGTAACGCCAGAATGGGGGTTTTCGCAACACGCTCTACTTTCCGCCCTAACCCAATTGGTATGTCGCTGGTAGAGCT
GAAAGAGGTTGTTTGCCATAAAGACAGCGTGATTCTGAAGCTCGGCAGTCTGGATCTGGTCGATGGTACGCCGGTAGTGG
ATATCAAACCGTATCTCCCCTTTGCCGAATCGCTTCCCGATGCCAGTGCCAGCTATGCGCAAAGTGCGCCAGCGGCAGAG
ATGGCGGTGAGTTTTACCGCAGAGGTCGAAAAGCAGCTTTTGACGCTGGAGAAGCGTTATCCGCAGTTAACGCTGTTTAT
CCGCGAAGTACTGGCGCAGGACCCACGCCCGGCCTATCGTAAAGGTGAGGAAACGGGCAAAACCTATGCCGTCTGGCTAC
ATGATTTTAACGTTCGCTGGCGCGTCACCGACGCAGGTTTTGAAGTCTTTGCGCTGGAACCGCGTTAA

Upstream 100 bases:

>100_bases
CCAATGCGGTATTACTGCATAGCTGCGAAGTCTCCAGCGGTACGCCAGGCTGCTATCGTCAGGCTGTATGTATCGGCTCT
GCGCTTAACATTACGGCGAA

Downstream 100 bases:

>100_bases
ATTCACGCCCTTCTCTTTTGACATTTCTTTTGCACTGGTAAACTAAATCACTTTTTTTTGTCCCAGGCTCGCCTTGAGCC
TGTTCTACCTTCCAACTGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRL
GGNARMGVFATRSTFRPNPIGMSLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNVRWRVTDAGFEVFALEPR

Sequences:

>Translated_235_residues
MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRL
GGNARMGVFATRSTFRPNPIGMSLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNVRWRVTDAGFEVFALEPR
>Mature_234_residues
SSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLG
GNARMGVFATRSTFRPNPIGMSLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAEM
AVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNVRWRVTDAGFEVFALEPR

Specific function: Unknown

COG id: COG1720

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0066 (virR) family

Homologues:

Organism=Homo sapiens, GI118600979, Length=135, Percent_Identity=40.7407407407407, Blast_Score=105, Evalue=3e-23,
Organism=Escherichia coli, GI1786393, Length=235, Percent_Identity=100, Blast_Score=484, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24586408, Length=163, Percent_Identity=41.1042944785276, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45552503, Length=142, Percent_Identity=43.6619718309859, Blast_Score=110, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YAEB_ECOLI (P28634)

Other databases:

- EMBL:   D15061
- EMBL:   L04474
- EMBL:   U70214
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C47040
- PIR:   C64744
- RefSeq:   AP_000856.1
- RefSeq:   NP_414737.1
- ProteinModelPortal:   P28634
- SMR:   P28634
- DIP:   DIP-11195N
- IntAct:   P28634
- STRING:   P28634
- EnsemblBacteria:   EBESCT00000000067
- EnsemblBacteria:   EBESCT00000015483
- GeneID:   949112
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0191
- KEGG:   eco:b0195
- EchoBASE:   EB1466
- EcoGene:   EG11503
- eggNOG:   COG1720
- GeneTree:   EBGT00050000011310
- HOGENOM:   HBG419053
- OMA:   SCFKEKF
- ProtClustDB:   CLSK879574
- BioCyc:   EcoCyc:EG11503-MONOMER
- Genevestigator:   P28634
- InterPro:   IPR001378
- TIGRFAMs:   TIGR00104

Pfam domain/function: PF01980 UPF0066

EC number: NA

Molecular weight: Translated: 26363; Mature: 26231

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS01318 UPF0066

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQADAVRGLEAFSHLWIL
CCCCCCHHHCCCCCCHHHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHH
FVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGMSLVELKEVVCHKDSVILK
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEE
LGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAEMAVSFTAEVEKQLLTLEKRY
ECCEEEECCCCEEEECCCCCHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
PQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNVRWRVTDAGFEVFALEPR
CHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEEEEECCEEEEEECCCEEEEEECCC
>Mature Secondary Structure 
SSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQADAVRGLEAFSHLWIL
CCCCCHHHCCCCCCHHHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHH
FVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGMSLVELKEVVCHKDSVILK
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEE
LGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAEMAVSFTAEVEKQLLTLEKRY
ECCEEEECCCCEEEECCCCCHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
PQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNVRWRVTDAGFEVFALEPR
CHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEEEEECCEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1459951; 9278503