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The map label for this gene is secM [H]

Identifier: 157159568

GI number: 157159568

Start: 109385

End: 109972

Strand: Direct

Name: secM [H]

Synonym: EcHS_A0103

Alternate gene names: 157159568

Gene position: 109385-109972 (Clockwise)

Preceding gene: 157159567

Following gene: 157159569

Centisome position: 2.36

GC content: 52.38

Gene sequence:

>588_bases
GTGCTGTGGACTGCAGGCTTTAATGATAAGATTTGTGCGCTAAATACGTTTGAATACGATCGGGATGGCAATAACGTGAG
TGGAATACTGACGCGCTGGCGACAGTTTGGTAAACGCTACTTCTGGCCGCATCTCTTATTAGGGATGGTTGCGGCGAGTT
TAGGTTTGCCTGCGCTCAGCAACGCCGCCGAACCAAACGCGCCCGCAAAAGCGACAACCCGCAACCACGAGCCTTCAGCC
AAAGTTAACTTTGGTCAATTGGCCTTGCTGGAAGCGAACACACGCCGCCCGAATTCGAACTATTCCGTTGATTACTGGCA
TCAACATGCCATTCGCACGGTAATCCGTCATCTTTCTTTCGCAATGGCACCGCAAACACTGCCCGTTGCTGAAGAATCTT
TGCCTCTTCAGGCGCAACATCTTGCATTACTGGATACGCTCAGCGCGCTGCTGACCCAGGAAGGCACTCCGTCTGAAAAG
GGTTATCGCATTGATTATGCGCATTTTACCCCACAAGCAAAATTCAGCACGCCCGTCTGGATAAGCCAGGCGCAAGGCAT
CCGTGCTGGCCCTCAACGCCTCACCTAA

Upstream 100 bases:

>100_bases
CAGGTGAACCAGTCGTTTTTTTTTGAATTTTATAAGAGCTATAAAAAACGGTGCGAACGCTGTTTTCTTAAGCACTTTTC
CGCACAACTTATCTTCATTC

Downstream 100 bases:

>100_bases
CAACAATAAACCTTTACTTCATTTTATTAACTCCGCAACGCGGGGCGTTTGAGATTTTATTATGCTAATCAAATTGTTAA
CTAAAGTTTTCGGTAGTCGT

Product: SecA regulator SecM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MLWTAGFNDKICALNTFEYDRDGNNVSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSA
KVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEK
GYRIDYAHFTPQAKFSTPVWISQAQGIRAGPQRLT

Sequences:

>Translated_195_residues
MLWTAGFNDKICALNTFEYDRDGNNVSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSA
KVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEK
GYRIDYAHFTPQAKFSTPVWISQAQGIRAGPQRLT
>Mature_195_residues
MLWTAGFNDKICALNTFEYDRDGNNVSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSA
KVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEK
GYRIDYAHFTPQAKFSTPVWISQAQGIRAGPQRLT

Specific function: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm, cytosol. Periplasm (By similarity). Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secM family [H]

Homologues:

Organism=Escherichia coli, GI87081686, Length=170, Percent_Identity=99.4117647058823, Blast_Score=347, Evalue=3e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009502
- ProDom:   PD089227 [H]

Pfam domain/function: PF06558 SecM [H]

EC number: NA

Molecular weight: Translated: 21739; Mature: 21739

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWTAGFNDKICALNTFEYDRDGNNVSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALS
CEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
NAAEPNAPAKATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSF
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVW
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHCCCCCCCCCCCEE
ISQAQGIRAGPQRLT
ECCCCCCCCCCCCCC
>Mature Secondary Structure
MLWTAGFNDKICALNTFEYDRDGNNVSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALS
CEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
NAAEPNAPAKATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSF
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVW
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHCCCCCCCCCCCEE
ISQAQGIRAGPQRLT
ECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA