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The map label for this gene is rutG [H]

Identifier: 157159382

GI number: 157159382

Start: 1146161

End: 1147489

Strand: Reverse

Name: rutG [H]

Synonym: EcE24377A_1124

Alternate gene names: 157159382

Gene position: 1147489-1146161 (Counterclockwise)

Preceding gene: 157158870

Following gene: 157158115

Centisome position: 23.04

GC content: 53.72

Gene sequence:

>1329_bases
ATGGCAATGTTCGGTTTTCCTCACTGGCAGTTAAAATCGACCTCTATAGAGAGCGGTGTGGTCGCGCCGGATGAACGATT
GCCGTTTGCTCAGACGGCAGTAATGGGCGTTCAACACGCGGTGGCGATGTTTGGCGCGACGGTGTTAATGCCGATTCTGA
TGGGGCTGGATCCCAATCTTTCCATTTTAATGTCGGGGATCGGCACGTTACTGTTTTTCTTTATTACCGGCGGGCGCGTC
CCCAGTTATCTCGGTTCCAGCGCGGCTTTTGTCGGCGTGGTGATTGCCGCGACGGGCTTTAACGGTCAGGGCATTAACCC
GAATATCAGCATTGCGCTGGGCGGGATTATCGCCTGTGGGCTGGTTTATACCGTCATTGGCCTGGTGGTGATGAAAATTG
GTACACGCTGGATTGAACGACTAATGCCGCCGGTGGTGACGGGTGCGGTGGTGATGGCGATTGGCCTGAACTTAGCGCCT
ATCGCAGTGAAAAGTGTATCGGCTTCGGCCTTTGATAGCTGGATGGCGGTAATGACGGTGCTGTGTATTGGGCTGGTGGC
GGTGTTTACCCGTGGCATGATCCAGCGGTTATTGATTCTCGTAGGTTTAATTGTCGCCTGTCTGCTGTATGGCGTGATGA
CCAACGTTTTAGGGCTGGGAAAAGCCGTCGATTTTACTCTCGTCAGCCATGCTGCCTGGTTCGGTCTGCCACATTTTTCC
ACTCCTGCTTTTAATGGTCAGGCAATGATGCTGATTGCGCCCGTGGCGGTGATTCTGGTGGCGGAAAACTTAGGTCATCT
CAAGGCAGTCGCCGGGATGACCGGACGCAATATGGACCCGTATATGGGGCGGGCATTCGTAGGCGATGGTCTGGCAACGA
TGCTTTCCGGCTCTGTCGGCGGTAGCGGCGTGACCACCTATGCTGAAAATATCGGTGTGATGGCCGTGACCAAAGTCTAC
TCGACGCTGGTGTTTGTTGCTGCTGCCGTCATCGCCATGCTGTTGGGCTTTTCGCCGAAATTTGGCGCGCTGATCCATAC
CATTCCTGCACCGGTGATTGGTGGTGCTTCAATTGTTGTGTTCGGGCTGATTGCCGTCGCAGGCGCAAGGATCTGGGTAC
AAAACCGTGTCGATTTAAGCCAGAACGGTAATTTGATTATGGTCGCAGTAACCTTAGTGCTGGGCGCGGGTGATTTTGCT
CTCACGCTGGGCGGTTTTACGTTGGGAGGGATTGGTACAGCAACCTTTGGCGCGATTTTACTCAATGCGTTGTTAAGCAG
AAAGTTGGTTGACGTTCCACCGCCAGAAGTTGTTCATCAGGAGCCATAA

Upstream 100 bases:

>100_bases
CGATTCATCGTCACGCCACACCCTACGGGCTGGTGTGGTTCGATCGCAGTTATCACGCGCTGATGCGCCCTGCTTGTTAA
CCTCCTTAAGGAGACAGCTG

Downstream 100 bases:

>100_bases
ACAGAAAACCGCCGGGATTACCGGCGGTGATGACTTTTTGACGAGCCTAAGAAAAAAATGCATTCGTCATTGATTAGCCC
GGCTAGTTGTCGCTTTTGCC

Product: putative purine permease ycdG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MAMFGFPHWQLKSTSIESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAAVIAMLLGFSPKFGALIHTIPAPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFA
LTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP

Sequences:

>Translated_442_residues
MAMFGFPHWQLKSTSIESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAAVIAMLLGFSPKFGALIHTIPAPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFA
LTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
>Mature_441_residues
AMFGFPHWQLKSTSIESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVP
SYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPI
AVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFST
PAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYS
TLVFVAAAVIAMLLGFSPKFGALIHTIPAPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFAL
TLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=442, Percent_Identity=99.5475113122172, Blast_Score=857, Evalue=0.0,
Organism=Escherichia coli, GI1788843, Length=425, Percent_Identity=37.1764705882353, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI87082181, Length=457, Percent_Identity=25.8205689277899, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082178, Length=407, Percent_Identity=26.7813267813268, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790087, Length=402, Percent_Identity=23.3830845771144, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71993493, Length=174, Percent_Identity=34.4827586206897, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17542260, Length=174, Percent_Identity=34.4827586206897, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17542262, Length=176, Percent_Identity=31.25, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=30.3867403314917, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17541904, Length=175, Percent_Identity=29.7142857142857, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356175, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45596; Mature: 45465

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AMFGFPHWQLKSTSIESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNL
CCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACG
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHEEEECCCCCCCCCCCEEHHHHHHHHH
LVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVG
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHCHHHHCCCHHHHHCCCCC
GSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAPVIGGASIVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHH
FGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAIL
HHHHHHHHHHEEEECCCCCCCCCCEEEEEHHHHHCCCCCEEEECCEEECCHHHHHHHHHH
LNALLSRKLVDVPPPEVVHQEP
HHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]