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The map label for this gene is ompA [H]

Identifier: 157159269

GI number: 157159269

Start: 1097662

End: 1098714

Strand: Reverse

Name: ompA [H]

Synonym: EcE24377A_1071

Alternate gene names: 157159269

Gene position: 1098714-1097662 (Counterclockwise)

Preceding gene: 157158913

Following gene: 157158226

Centisome position: 22.06

GC content: 53.37

Gene sequence:

>1053_bases
ATGAAAAAGACAGCTATCGCGATTGCAGTGGCACTGGCTGGTTTCGCTACCGTAGCGCAGGCCGCTCCGAAAGATAACAC
CTGGTACACTGGTGCTAAACTGGGCTGGTCCCAGTACCATGACACTGGTTTTATTCCTAACAATGGTCCGACCCACGAAA
ACCAACTGGGTGCAGGTGCTTTTGGTGGTTACCAGGTTAACCCGTATGTTGGTTTTGAAATGGGTTACGACTGGTTAGGT
CGTATGCCGTACAAAGGCGACAACATCAACGGAGCATACAAAGCTCAGGGCGTTCAACTGACTGCTAAACTGGGTTACCC
AATCACTGACGATCTGGACGTATACACTCGTCTGGGTGGTATGGTATGGCGTGCAGACACCAAGGCTAACGTACCTGGTG
GCGCATCCTTTAAAGACCACGACACTGGCGTTTCTCCGGTTTTCGCAGGTGGTGTTGAGTACGCGATCACTCCTGAAATC
GCTACCCGTCTGGAATACCAGTGGACCAACAACATCGGTGACGCAAACACCATCGGTACTCGTCCGGACAACGGTCTGCT
GAGCCTGGGTGTTTCCTACCGTTTCGGTCAGGGCGAAGCAGCTCCGGTAGTTGCTCCGGCTCCAGCTCCGGCACCGGAAG
TACAGACCAAGCACTTCACTCTGAAGTCTGACGTTCTGTTCAACTTCAACAAAGCAACCCTGAAACCGGAAGGTCAGGCT
GCTCTGGATCAGCTGTACAGCCAGCTGAGCAACCTGGATCCGAAAGACGGTTCCGTAGTTGTTCTGGGTTACACTGACCG
CATCGGTTCTGACGCTTACAACCAGGGTCTGTCCGAGCGCCGTGCTCAGTCTGTTGTTGATTACCTGATCTCCAAAGGTA
TCCCGGCAGACAAGATCTCCGCACGTGGTATGGGCGAATCCAACCCGGTTACTGGCAACACCTGTGACAACGTGAAACAG
CGTGCTGCACTGATCGACTGCCTGGCTCCGGATCGTCGCGTAGAGATCGAAGTTAAAGGCATCAAAGACGTTGTAACTCA
GCCGCAGGCTTAA

Upstream 100 bases:

>100_bases
GTAGAGTTAATATTGAGCAGATCCCCCGGTGAAGGATTTAACCGTGTTATCTCGTTGGAGATATTCATGGCGTATTTTGG
ATGATAACGAGGCGCAAAAA

Downstream 100 bases:

>100_bases
GTTCTCGTCTGGTAGAAAAACCCCGCAGCTGCGGGGTTTTTTTCGCCTTTAGTAAATTGAACTGACTTCGTCAGTTATTC
CTTACCCAGCAATGCCTGCA

Product: outer membrane protein A

Products: NA

Alternate protein names: Outer membrane protein II [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLG
RMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEI
ATRLEYQWTNNIGDANTIGTRPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQA
ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQ
RAALIDCLAPDRRVEIEVKGIKDVVTQPQA

Sequences:

>Translated_350_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLG
RMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEI
ATRLEYQWTNNIGDANTIGTRPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQA
ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQ
RAALIDCLAPDRRVEIEVKGIKDVVTQPQA
>Mature_350_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLG
RMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEI
ATRLEYQWTNNIGDANTIGTRPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQA
ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQ
RAALIDCLAPDRRVEIEVKGIKDVVTQPQA

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=350, Percent_Identity=96, Blast_Score=655, Evalue=0.0,
Organism=Escherichia coli, GI48994946, Length=120, Percent_Identity=35.8333333333333, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 37437; Mature: 37437

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS01068 OMPA_1 ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGA
CCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
FGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGG
CCCEEECCEEEHCCCHHHHCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCHHHHHHHCC
MVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDANTIGT
EEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCEEECHHHHHHEEEEECCCCCCCCCCCC
RPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQA
CCCCCEEEECEEEEECCCCCCCEEECCCCCCCCCCCEEEEEECCEEEECCCCCCCCCCHH
ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKIS
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
ARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCC
>Mature Secondary Structure
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGA
CCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
FGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGG
CCCEEECCEEEHCCCHHHHCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCHHHHHHHCC
MVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDANTIGT
EEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCEEECHHHHHHEEEEECCCCCCCCCCCC
RPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQA
CCCCCEEEECEEEEECCCCCCCEEECCCCCCCCCCCEEEEEECCEEEECCCCCCCCCCHH
ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKIS
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
ARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1955870 [H]