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The map label for this gene is yihQ [H]

Identifier: 157159043

GI number: 157159043

Start: 4392303

End: 4394339

Strand: Reverse

Name: yihQ [H]

Synonym: EcE24377A_4401

Alternate gene names: 157159043

Gene position: 4394339-4392303 (Counterclockwise)

Preceding gene: 157155053

Following gene: 157155703

Centisome position: 88.25

GC content: 53.41

Gene sequence:

>2037_bases
ATGGATACGCCACGTCCACAGTTATTAGATTTTCAATTTCATCAGAATAACGACAGTTTTACCCTACATTTTCAACAACG
TCTTATTTTAACCCATAGCAAAGATAATCCTTGTTTATGGATTGGCTCAGGTATAGCGGATATCGATATGTTCCGCGGTA
ATTTCAGCATTAAAGATAAACTACAGGAGAAAATTGCGCTTACCGACGCCATCGTCAGCCAGTCACCGGATGGTTGGTTA
ATTCATTTCAGCCGTGGTTCTGACATTAGCGCCACGCTGAATATCTCTGCCGACGATCAGGGCCGTTTATTGCTGGAACT
ACAAAACGACAACCTTAACCACAACCGTATCTGGCTGCGCCTTGCCGCTCAACCAGAGGACCATATCTACGGCTGCGGCG
AACAGTTTTCCTACTTCGATCTGCGTGGCAAACCGTTCCCGCTATGGACCAGTGAACAAGGCGTTGGTCGCAACAAACAA
ACCTATGTCACCTGGCAGGCCGACTGCAAAGAAAATGCGGGCGGCGACTATTACTGGACTTTCTTCCCACAGCCTACGTT
TGTCAGCACGCAGAAGTATTACTGCCATGTTGATAACAGTTGCTATATGAACTTCGACTTTAGTGCCCCGGAATACCATG
AACTGGCGCTGTGGGAAGACAAAGCAACGCTGCGTTTTGAATGTGCTGACACATACATTTCCCTGCTGGAAAAATTAACC
GCCCTGCTGGGACGCCAGCCAGAACTGCCCGACTGGATTTATGACGGAGTAACGCTCGGCATTCAGGGCGGGACGGAAGT
GTGCCAGAAGAAACTGGACACCATGCGTAACGCGGGCGTGAAGGTCAACGGCATCTGGGCGCAGGACTGGTCCGGTATTC
GTATGACCTCTTTTGGCAAACGCGTGATGTGGAACTGGAAGTGGAACAGCGAAAACTACCCGCAACTGGATTCACGCATT
AAGCAGTGGAATCAGGAGGGCGTGCAGTTCCTGGCCTATATCAACCCGTATGTTGCCAGCGATAAAGATCTCTGCGAAGA
AGCGGCACAACACGGCTATCTGGCAAAAGATGCCTCTGGCGGTGACTATCTGGTGGAGTTTGGCGAGTTTTACGGCGGCG
TTGTCGATCTCACTAATCCAGAAGCCTACGCCTGGTTCAAGGAAGTGATCAAAAAGAACATGATTGAACTCGGCTGCGGC
GGCTGGATGGCTGACTTCGGCGAGTATCTGCCCACCGACACGTACCTGCATAACGGCGTCAGTGCCGAAATTATGCATAA
CGCCTGGCCTGCGCTGTGGGCGAAGTGTAACTACGAAGCCCTTGAAGAAACGGGCAAGCTCGGCGAGATCCTTTTCTTTA
TGCGCGCCGGTTCTACCGGTAGCCAGAAATACTCCACCATGATGTGGGCGGGCGACCAGAACGTCGACTGGAGTCTCGAC
GATGGCCTGGCGTCGGTTGTCCCGGCGGCGCTGTCGCTGGCAATGACCGGACATGGCCTGCACCACAGCGACATTGGCGG
TTACACCACCCTGTTTGAGATGAAGCGCAGCAAAGAGCTGCTGCTGCGCTGGTGCGATTTCAGCGCCTTCACGCCGATGA
TGCGCACCCACGAAGGTAACCGTCCTGGCGACAACTGGCAGTTTGACGGCGACGCAGAAACTATCGCCCATTTTGCCCGT
ATGACCTCCGTCTTCACCACCCTGAAACCTTACCTGAAAGAGGCTGTCGCGCTGAATGCGAAGTCCGGCCTGCCGGTTAT
GCGCCCGCTGTTCCTGCATTACGAAGACGATGCGCACACTTACACCCTGAAATATCAGTACCTGTTAGGTCGCGACATTC
TGGTCGCTCCGGTGCATGAAGAAGGCCGTAGCGACTGGACGCTCTATCTGCCGGAGGATAACTGGGTCCACGCCTGGACG
GGTGAAGCGTTCCGGGGCGGGGAAGTTACCGTTAATGCGCCCATCGGCAAGCCGCCGGTCTTTTATCGCGCCGATAGCGA
ATGGGCGGCACTGTTCGCGTCGTTAAAAAGCATCTAA

Upstream 100 bases:

>100_bases
CTGTAAAGTTTTTATATATCAGTTTTATGAGAATCATTTTACATAAGCCTGTAATAACAGGAAGGCAACAATCTCGTTCT
CAACTCTATGGAGATTAGTT

Downstream 100 bases:

>100_bases
TCACATCCGCCCGTGGGGAAACTCATGGGCAAAGGGAGAACATCGATGAGTCACATCACAACGGAAGATCCAGCAACTTT
ACGCCTGCCCTTTAAAGAGA

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MDTPRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNQEGVQFLAYINPYVASDKDLCEEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTSVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI

Sequences:

>Translated_678_residues
MDTPRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNQEGVQFLAYINPYVASDKDLCEEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTSVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI
>Mature_678_residues
MDTPRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNQEGVQFLAYINPYVASDKDLCEEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTSVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI

Specific function: Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI153791946, Length=349, Percent_Identity=24.6418338108883, Blast_Score=109, Evalue=8e-24,
Organism=Homo sapiens, GI88900491, Length=351, Percent_Identity=25.9259259259259, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI38202257, Length=351, Percent_Identity=25.9259259259259, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI66346737, Length=397, Percent_Identity=25.6926952141058, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI119393895, Length=407, Percent_Identity=22.8501228501229, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI119393893, Length=407, Percent_Identity=22.8501228501229, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI119393891, Length=407, Percent_Identity=22.8501228501229, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI221316699, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310115361, Length=236, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI2367323, Length=678, Percent_Identity=99.8525073746313, Blast_Score=1417, Evalue=0.0,
Organism=Escherichia coli, GI2367256, Length=550, Percent_Identity=24.5454545454545, Blast_Score=176, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17560798, Length=380, Percent_Identity=22.6315789473684, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560800, Length=380, Percent_Identity=22.6315789473684, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71991189, Length=366, Percent_Identity=24.5901639344262, Blast_Score=96, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI32563849, Length=231, Percent_Identity=30.7359307359307, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71985706, Length=237, Percent_Identity=29.1139240506329, Blast_Score=80, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319706, Length=381, Percent_Identity=22.0472440944882, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24650054, Length=345, Percent_Identity=25.5072463768116, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643749, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24643753, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24643751, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24643746, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357605, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571440, Length=379, Percent_Identity=20.5804749340369, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571438, Length=378, Percent_Identity=20.6349206349206, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 77261; Mature: 77261

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDK
CCCCCCCEEEEEEECCCCCEEEEEEEEEEEEECCCCCEEEEECCCCEEEEECCCCCHHHH
LQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLR
HHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEE
LAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ECCCCCEEECCEEEEEECCEEEEEECCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEECCCC
RVMWNWKWNSENYPQLDSRIKQWNQEGVQFLAYINPYVASDKDLCEEAAQHGYLAKDASG
EEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHCCCEEECCCC
GDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCGGWMADFGEYLPTDTYLHNGV
CHHEEEHHHHCCCEEECCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTSVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCEE
YTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPV
EEEEEEEEECCCEEEEECCCCCCCCEEEECCCCCEEEEECCCCCCCCEEEEECCCCCCCE
FYRADSEWAALFASLKSI
EEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MDTPRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDK
CCCCCCCEEEEEEECCCCCEEEEEEEEEEEEECCCCCEEEEECCCCEEEEECCCCCHHHH
LQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLR
HHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEE
LAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ECCCCCEEECCEEEEEECCEEEEEECCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEECCCC
RVMWNWKWNSENYPQLDSRIKQWNQEGVQFLAYINPYVASDKDLCEEAAQHGYLAKDASG
EEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHCCCEEECCCC
GDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCGGWMADFGEYLPTDTYLHNGV
CHHEEEHHHHCCCEEECCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTSVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCEE
YTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPV
EEEEEEEEECCCEEEEECCCCCCCCEEEECCCCCEEEEECCCCCCCCEEEEECCCCCCCE
FYRADSEWAALFASLKSI
EEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]