| Definition | Escherichia coli E24377A, complete genome. |
|---|---|
| Accession | NC_009801 |
| Length | 4,979,619 |
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The map label for this gene is tdcG [H]
Identifier: 157158880
GI number: 157158880
Start: 3593162
End: 3594526
Strand: Reverse
Name: tdcG [H]
Synonym: EcE24377A_3586
Alternate gene names: 157158880
Gene position: 3594526-3593162 (Counterclockwise)
Preceding gene: 157157021
Following gene: 157155356
Centisome position: 72.18
GC content: 53.55
Gene sequence:
>1365_bases ATGATTAGTGCATTCGATATTTTCAAAATTGGGATTGGTCCCTCCAGTTCGCATACCGTGGGGCCAATGAATGCCGGAAA AAGTTTTATTGATCGGCTGGAAAGTAGCGGCTTATTAACCGCGACGAGCCATATTGTGGTCGATCTGTATGGGTCGTTGT CACTGACGGGCAAAGGCCATGCCACGGATGTCGCCATTATCATGGGACTGGCAGGAAACAGTCCGCAGGATGTTGTCATT GATGAGATCCCTGCATTTATAGAGTTAGTAACGCGCAGCGGGCGGCTGCCAGTGGCATCTGGTGCGCATATTGTTGATTT TCCTGTAGCAAAGAACATTATCTTCCATCCCGAAATGTTGCCTCGCCATGAGAACGGAATGCGGATCACTGCCTGGAAGG GACAGGAAGCGCTATTAAGTAAAACCTATTACTCTGTCGGCGGCGGGTTTATTGTCGAAGAAGAACACTTCGGCCTGTCG CACGATGTCGAAACGTCCGTACCTTACGATTTCCACTCAGCAGGTGAACTGCTGAAAATGTGTGATTACAACGGCCTGTC TATATCTGGCCTGATGATGCACAACGAGCTGGCGCTGCGCAGCAAAGCGGAAATTGACGCAGGGTTTGCCCGTATCTGGC AAGTGATGCATGACGGTATTGAACGCGGGATGAACACTGAAGGCGTGCTGCCTGGTCCGCTCAATGTGCCGCGTCGTGCC GTAGCGCTGCGTCGTCAGCTGGTTTCCAGCGATAACATCTCTAACGATCCGATGAATGTCATCGACTGGATCAACATGTA CGCGCTGGCGGTTAGTGAAGAAAACGCAGCTGGCGGGCGCGTGGTAACGGCACCGACTAACGGTGCGTGCGGCATTATTC CGGCAGTGCTGGCTTATTACGATAAGTTCCGTCGTCCGGTAAACGAGCGGTCAATTGCCCGCTATTTTCTGGCAGCGGGG GCTATTGGCGCGCTGTATAAAATGAACGCCTCCATCTCTGGCGCGGAGGTCGGCTGTCAGGGGGAGATTGGCGTGGCCTG TTCAATGGCGGCGGCAGGGTTAACTGAACTACTGGGCGGCAGTCCGGCGCAGGTATGCAATGCGGCGGAAATCGCGATGG AGCATAACCTTGGGCTGACCTGCGATCCGGTTGCCGGACAGGTACAAATCCCGTGCATTGAACGTAATGCCATTAATGCC GTGAAAGCAGTAAACGCCGCGCGGATGGCGATGCGCCGCACCTCGGCACCGCGTGTTTCACTCGATAAAGTGATCGAGAC GATGTATGAAACCGGCAAAGATATGAACGATAAATACCGCGAAACATCACGCGGAGGACTGGCCATTAAAGTGGTCTGCG GCTGA
Upstream 100 bases:
>100_bases TTGAAGCTATCGCAGTACGTAGTGCGTAAAGCCTCGTGAGCGGGACGGTCGCAAGGTCGTTCCGCTCCACTTCACTGAAC GGCAATCCGAGGGTGTGGAT
Downstream 100 bases:
>100_bases CATTGCTGTCAGCTTTCATCCTTGGGTGCACAAATGTGCACCTTTTTTTTGTGATCTGCCGCAAATAGAGAATGAATATT CTCTTGCGATTAATTTAGTA
Product: L-serine dehydratase tdcG
Products: NA
Alternate protein names: SDH; L-serine deaminase [H]
Number of amino acids: Translated: 454; Mature: 454
Protein sequence:
>454_residues MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVI DEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRA VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAG AIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA VKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
Sequences:
>Translated_454_residues MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVI DEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRA VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAG AIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA VKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG >Mature_454_residues MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVI DEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRA VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAG AIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA VKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
Specific function: Anaerobic degradation of L-threonine to propionate. [C]
COG id: COG1760
COG function: function code E; L-serine deaminase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]
Homologues:
Organism=Escherichia coli, GI48994925, Length=454, Percent_Identity=99.7797356828194, Blast_Score=931, Evalue=0.0, Organism=Escherichia coli, GI1788116, Length=453, Percent_Identity=73.9514348785872, Blast_Score=681, Evalue=0.0, Organism=Escherichia coli, GI1789161, Length=452, Percent_Identity=72.787610619469, Blast_Score=672, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004644 - InterPro: IPR005130 - InterPro: IPR005131 [H]
Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]
EC number: =4.3.1.17 [H]
Molecular weight: Translated: 48464; Mature: 48464
Theoretical pI: Translated: 6.24; Mature: 6.24
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 4.2 %Met (Translated Protein) 5.9 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 4.2 %Met (Mature Protein) 5.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGH CCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCEEEEEEECCEEECCCCC ATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEML CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEECCCCC PRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKM CCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH CDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRA HCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYY HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHH DKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGG HHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC SPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVS CHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCC LDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEC >Mature Secondary Structure MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGH CCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCEEEEEEECCEEECCCCC ATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEML CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEECCCCC PRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKM CCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH CDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRA HCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYY HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHH DKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGG HHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC SPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVS CHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCC LDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9278503; 9484901 [H]