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The map label for this gene is agaR [H]

Identifier: 157158868

GI number: 157158868

Start: 3612733

End: 3613542

Strand: Reverse

Name: agaR [H]

Synonym: EcE24377A_3611

Alternate gene names: 157158868

Gene position: 3613542-3612733 (Counterclockwise)

Preceding gene: 157157560

Following gene: 157155355

Centisome position: 72.57

GC content: 52.47

Gene sequence:

>810_bases
ATGAGTAATACCGACGCTTCAGGTGAGAAGCGAGTGACTGGCACCAGCGAGCGACGAGAACAGATCATTCAGCGTCTGCG
ACAGCAAGGGAGTGTGCAGGTTAACGATCTGTCGGCATTGTATGGCGTATCTACTGTGACGATCCGCAATGATCTGGCGT
TTCTGGAAAAGCAGGGGATCGCTGTGCGTGCCTATGGTGGCGCGTTGATCTGCGATAGCACGACGCCGCCAGTCGAGCCA
TCAGTGGAAGATAAAAGCGCGCTGAACACCGCGATGAAACGCAGCGTTGCGAAAGCTGCCGTTGAGTTGATTCAGCCAGG
TCATCGGGTGATCCTCGATTCCGGGACCACCACTTTTGAGATTGCTCGTCTGATGCGCAAGCACACTGACGTAATTGCGA
TGACCAACGGTATGAACGTGGCTAATGCGTTGCTGGAAGCGGAAGGCGTTGAGCTGCTGATGACCGGCGGGCATTTGCGC
CGTCAGTCGCAATCTTTTTACGGCGATCAGGCTGAGCAATCGCTGCAAAATTACCACTTCGATATGCTGTTTCTTGGTGT
AGATGCGATCGATCTGGAGCGCGGCGTCAGCACACATAATGAAGATGAAGCCCGTTTAAACCGTCGGATGTGCGAAGTTG
CGGAACGGATCATCGTCGTCACCGATTCCAGTAAGTTCAATCGTTCCAGTTTACATAAGATCATTGATACTCAATGTATC
GACATGATCATTGTTGATGAAGGCATTCCTGCGGATAGCCTGGAAGGACTGCGAAAGGCTGGGGTTGAAGTGATTCTGGT
CGGGGAGTGA

Upstream 100 bases:

>100_bases
GTAGCTTGCGTCAATGGGCAAGGTGGGCTTGCATTTGCTTAATAGAAAGGCGTTAATAGGCAAAACGAAATGAAACGAAA
GTTTTACGAAAGGACTTACT

Downstream 100 bases:

>100_bases
GAAAGGGTGCCCGCTGGTCAACACGAATACGTTCGGCGGGCATTGTGAACACCATCAATGGTTTTCTTCTGTCTCTTGGG
TGAGGCTTTCCCAGTCGGCA

Product: DNA-binding transcriptional regulator AgaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPPVEP
SVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQCI
DMIIVDEGIPADSLEGLRKAGVEVILVGE

Sequences:

>Translated_269_residues
MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPPVEP
SVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQCI
DMIIVDEGIPADSLEGLRKAGVEVILVGE
>Mature_268_residues
SNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPPVEPS
VEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRR
QSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQCID
MIIVDEGIPADSLEGLRKAGVEVILVGE

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=269, Percent_Identity=99.2565055762082, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=35.4330708661417, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=30.0395256916996, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789829, Length=251, Percent_Identity=27.8884462151394, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787540, Length=251, Percent_Identity=31.4741035856574, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=27.3809523809524, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788069, Length=250, Percent_Identity=25.2, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790753, Length=250, Percent_Identity=26.4, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787063, Length=240, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789170, Length=237, Percent_Identity=25.7383966244726, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29530; Mature: 29399

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHCCEEEEEEHHHHHHHHCCE
AVRAYGGALICDSTTPPVEPSVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFE
EEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
IARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQNYHF
HHHHHHHCCCEEEEECCCHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHHHCCC
DMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQCI
EEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHH
DMIIVDEGIPADSLEGLRKAGVEVILVGE
EEEEECCCCCHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure 
SNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGI
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHCCEEEEEEHHHHHHHHCCE
AVRAYGGALICDSTTPPVEPSVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFE
EEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
IARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQNYHF
HHHHHHHCCCEEEEECCCHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHHHCCC
DMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQCI
EEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHH
DMIIVDEGIPADSLEGLRKAGVEVILVGE
EEEEECCCCCHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]