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The map label for this gene is yjgB [H]

Identifier: 157158628

GI number: 157158628

Start: 4830639

End: 4831658

Strand: Reverse

Name: yjgB [H]

Synonym: EcE24377A_4837

Alternate gene names: 157158628

Gene position: 4831658-4830639 (Counterclockwise)

Preceding gene: 157157242

Following gene: 157158413

Centisome position: 97.03

GC content: 54.8

Gene sequence:

>1020_bases
ATGTCGATGATAAAAAGCTATGCCGCAAAAGAAGCGGGCGGCGAACTGGAAGTTTATGAGTACGATCCCGGTGAGCTGAA
GCCACAAGATGTTGAAGTGCAGGTGGATTACTGCGGGATTTGTCATTCCGATCTGTCGATGATCGATAACGAATGGGGAT
TTTCACAATATCCGCTGGTTGCCGGGCATGAGGTGATTGGGCGCGTGGTGGCACTCGGGAGCGCCGCGCAGGATAAAGGT
TTGCAGGTCGGTCAGCGTGTCGGGATTGGCTGGACGGCGCGTAGCTGTGGTCACTGCGACGCCTGTATTAGCGGTAATCA
GATCAACTGCGAGCAAGGTGCGGTGCCGACGATTATGAATCGCGGTGGCTTTGCCGAGAAGTTGCGTGCGGGCTGGCAAT
GGGTGATTCCACTGCCAGAAAATATTGATATCGAGTCCGCCGGGCCGCTGTTGTGCGGCGGTATCACGGTCTTTAAACCA
CTGTTGATGCACCATATCACTGCTACCAGCCGCGTTGGGGTAATTGGTATTGGCGGGCTGGGGCATATCGCTATAAAACT
TCTGCACGCAATGGGATGCGAGGTGACGGCCTTTAGTTCTAATCCGGCGAAAGAGCAGGAAGTACTGGCGATGGGTGCCG
ATAAAGTGGTGAATAGCCGCGATCCGCAGGCACTGAAAGCCCTGTCGGGGCAGTTTGATCTCATTATCAATACTGTGAAC
GTCAGCCTCGACTGGCAGCCTTATTTTGAGGCGCTGACCTATGGCGGTAATTTCCATACGGTCGGTGCGGTTCTCACGCC
GCTGTCTGTTCCGGCCTTTACGTTAATTGCGGGCGACCGCAGCATCTCTGGTTCTGCTACCGGCACGCCTTATGAGCTGC
GAAAGCTGATGCGCTTTGCCGCCCGCAGCAAGGTTGCGCCGACAACCGAACTGTTCCCGATGTCGAAAATTAACGACGCC
ATTCAGCATGTACGCGATGGTAAAGCTCGCTACCGAGTAGTCCTGAAAGCCGACTTCTGA

Upstream 100 bases:

>100_bases
TCAGCATTACACTCAGCGATATGTAACCTTTGTCACACTCCAGGCACCCCGCCCTGCCATGCTCTACACTTCCCAAACAA
CACCAGAGAAGGACCCAAAA

Downstream 100 bases:

>100_bases
TCCCTTTGCCGGGTGCTGTCGCCCGGCACTTAAATCTCTTTGGAAGGCGTCTCGCAATCTGCTGAATTTAGCGGTGAAGA
GTGCACAGCCGTTGCCTATA

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKG
LQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRAGWQWVIPLPENIDIESAGPLLCGGITVFKP
LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVN
VSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDA
IQHVRDGKARYRVVLKADF

Sequences:

>Translated_339_residues
MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKG
LQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRAGWQWVIPLPENIDIESAGPLLCGGITVFKP
LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVN
VSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDA
IQHVRDGKARYRVVLKADF
>Mature_338_residues
SMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGL
QVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRAGWQWVIPLPENIDIESAGPLLCGGITVFKPL
LMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVNV
SLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAI
QHVRDGKARYRVVLKADF

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082401, Length=339, Percent_Identity=98.8200589970501, Blast_Score=697, Evalue=0.0,
Organism=Escherichia coli, GI1786518, Length=346, Percent_Identity=35.2601156069364, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI87081918, Length=318, Percent_Identity=27.9874213836478, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788075, Length=342, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI226510992, Length=285, Percent_Identity=25.2631578947368, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790718, Length=325, Percent_Identity=25.8461538461538, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=333, Percent_Identity=29.1291291291291, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562584, Length=341, Percent_Identity=28.4457478005865, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562582, Length=335, Percent_Identity=27.4626865671642, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323980, Length=330, Percent_Identity=31.8181818181818, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319949, Length=339, Percent_Identity=33.3333333333333, Blast_Score=156, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323961, Length=337, Percent_Identity=29.9703264094956, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319621, Length=344, Percent_Identity=30.2325581395349, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324486, Length=340, Percent_Identity=27.9411764705882, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6323729, Length=336, Percent_Identity=27.3809523809524, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36446; Mature: 36315

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLV
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCEE
AGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMN
HHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEECCCCCCCHHHCCCCCCCCCCCCCCHHHC
RGGFAEKLRAGWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGL
CCCHHHHHHCCCEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCEEEECCH
GHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVN
HHHHHHHHHHHCCEEEEECCCCCCHHHHHHHCHHHHCCCCCHHHHHHHCCCEEEEEEEEE
VSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSISGSATGTPYELRKLMRFA
EEECCHHHHHHHHCCCCEEEHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
ARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADF
HHCCCCCCHHCCCHHHHHHHHHHHHCCCEEEEEEEEECC
>Mature Secondary Structure 
SMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLV
CHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCEE
AGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMN
HHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEECCCCCCCHHHCCCCCCCCCCCCCCHHHC
RGGFAEKLRAGWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGL
CCCHHHHHHCCCEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCEEEECCH
GHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVN
HHHHHHHHHHHCCEEEEECCCCCCHHHHHHHCHHHHCCCCCHHHHHHHCCCEEEEEEEEE
VSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSISGSATGTPYELRKLMRFA
EEECCHHHHHHHHCCCCEEEHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
ARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADF
HHCCCCCCHHCCCHHHHHHHHHHHHCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]