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The map label for this gene is yphD

Identifier: 157158445

GI number: 157158445

Start: 2825746

End: 2826744

Strand: Reverse

Name: yphD

Synonym: EcE24377A_2831

Alternate gene names: 157158445

Gene position: 2826744-2825746 (Counterclockwise)

Preceding gene: 157154916

Following gene: 157158660

Centisome position: 56.77

GC content: 56.56

Gene sequence:

>999_bases
ATGTCTGCTTCGTCATTACCATTGCCGCAGGGCAAGAGCGTCTCGCTCAAACAATTTGTCAGTCGCCATATTAATGAGAT
CGGTTTGCTGGTGGTGATTGCCATTCTTTATCTGGTCTTCTCCCTGAACGCGCCTGGCTTTATCTCATTGAATAACCAGA
TGAACGTGCTGCGCGATGCCGCCACCATTGGGATTGCCGCCTGGGCGATGACGCTGATTATTATCTCCGGTGAGATTGAT
GTCAGCGTTGGGCCGATGGTGGCTTTTGTCTCGGTGTGCCTGGCATTTTTGCTGCAATTTGAAGTTCCGCTGGCGGTGGC
GTGTCTGCTGGTGTTGCTGTTAGGCGCGCTGATGGGAACGCTGGCCGGGGTGCTGCGCGGCGTGTTTAACGTACCAAGTT
TCGTTGCCACACTGGGGCTGTGGAGCGCCCTGCGCGGAATGGGGCTGTTTATGACGAACGCACTGCCAGTGCCGATTGAC
GAAAACGAGGTGCTGGACTGGCTGGGCGGACAATTTCTCGGTGTGCCGGTATCCGCGCTGATCATGATTGTGTTGTTTGC
GCTGTTTGTGTTCATCAGCCGCAAAACCGCCTTCGGGCGCTCGGTTTTTGCCGTTGGCGGTAATGCTACGGCGGCGCAGT
TGTGCGGCATCAACGTTCGTCGGGTGCGCATTCTTATCTTTACCCTTTCGGGATTATTAGCGGCGGTGACCGGCATTTTG
TTGGCGGCGCGCCTCGGTTCTGGTAACGCAGGTGCCGCAAACGGTCTGGAGTTTGACGTCATCGCCGCGGTCGTGGTCGG
CGGTACGGCACTTTCCGGCGGTCGCGGTTCCCTGTTCGGTACATTGCTTGGTGTGCTGGTGATTACGCTAATCGGTAACG
GTCTGGTGCTGCTCGGGATTAACTCCTTTTTCCAGCAGGTGGTGCGCGGCGTCATCATCGTGGTGGCGGTGCTGGCGAAT
ATCTTGCTGACCCAGCGTAGCAGTAAAGCGAAACGCTAA

Upstream 100 bases:

>100_bases
CGGCACGTTCTCGCAGGAGTTTCACTCGCCGGTCAATGTGGATGAGCTGATGTCCGCCATTCTGTCTGTGCACTGATGAA
TTTTACCGAGGAACCTGAAG

Downstream 100 bases:

>100_bases
ACCTTAACGCCCCTGGCGCGGGTGCGGCAGGGATGAAAATTAATCGTATTGTTAATGAGGGATTTATGAAAACGATGCTG
GCAGCTTATTTACCAGGAAA

Product: putative sugar ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNAPGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEID
VSVGPMVAFVSVCLAFLLQFEVPLAVACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPID
ENEVLDWLGGQFLGVPVSALIMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGINVRRVRILIFTLSGLLAAVTGIL
LAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRGSLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLAN
ILLTQRSSKAKR

Sequences:

>Translated_332_residues
MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNAPGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEID
VSVGPMVAFVSVCLAFLLQFEVPLAVACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPID
ENEVLDWLGGQFLGVPVSALIMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGINVRRVRILIFTLSGLLAAVTGIL
LAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRGSLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLAN
ILLTQRSSKAKR
>Mature_331_residues
SASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNAPGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDV
SVGPMVAFVSVCLAFLLQFEVPLAVACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPIDE
NEVLDWLGGQFLGVPVSALIMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGINVRRVRILIFTLSGLLAAVTGILL
AARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRGSLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANI
LLTQRSSKAKR

Specific function: Probably part of the binding-protein-dependent transport system yphDEF. Probably responsible for the translocation of the substrate across the membrane

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily

Homologues:

Organism=Escherichia coli, GI1788896, Length=332, Percent_Identity=100, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1790191, Length=315, Percent_Identity=39.3650793650794, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI87082395, Length=287, Percent_Identity=36.5853658536585, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI145693152, Length=311, Percent_Identity=31.8327974276527, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789992, Length=138, Percent_Identity=41.304347826087, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790524, Length=304, Percent_Identity=29.2763157894737, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787793, Length=275, Percent_Identity=34.9090909090909, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693214, Length=257, Percent_Identity=35.7976653696498, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788471, Length=332, Percent_Identity=31.9277108433735, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787794, Length=318, Percent_Identity=29.2452830188679, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YPHD_ECOLI (P77315)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   A65032
- RefSeq:   AP_003132.1
- RefSeq:   NP_417041.1
- ProteinModelPortal:   P77315
- STRING:   P77315
- EnsemblBacteria:   EBESCT00000002109
- EnsemblBacteria:   EBESCT00000015827
- GeneID:   949063
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2530
- KEGG:   eco:b2546
- EchoBASE:   EB3238
- EcoGene:   EG13465
- eggNOG:   COG1172
- GeneTree:   EBGT00050000010181
- HOGENOM:   HBG663180
- OMA:   GPMVAFI
- ProtClustDB:   CLSK880428
- BioCyc:   EcoCyc:YPHD-MONOMER
- Genevestigator:   P77315
- InterPro:   IPR001851

Pfam domain/function: PF02653 BPD_transp_2

EC number: NA

Molecular weight: Translated: 34484; Mature: 34353

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f821848)-; HASH(0x1f7bd7cc)-; HASH(0x1f539ac8)-; HASH(0x1fa9cb78)-; HASH(0x1f51d41c)-; HASH(0x1fb72440)-; HASH(0x1edf58d4)-; HASH(0x1eb09d08)-; HASH(0x1f927f08)-; HASH(0x1f31d9f4)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNAPGFISLNNQMNVLRDA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
ATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEVPLAVACLLVLLLGALMGT
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPIDENEVLDWLGGQFLGVPVSAL
HHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHCCCEECCCHHHH
IMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGINVRRVRILIFTLSGLLAAVTGIL
HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRGSLFGTLLGVLVITLIGNGLVLLGI
HHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEH
NSFFQQVVRGVIIVVAVLANILLTQRSSKAKR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
SASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNAPGFISLNNQMNVLRDA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
ATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEVPLAVACLLVLLLGALMGT
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPIDENEVLDWLGGQFLGVPVSAL
HHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHCCCEECCCHHHH
IMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGINVRRVRILIFTLSGLLAAVTGIL
HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRGSLFGTLLGVLVITLIGNGLVLLGI
HHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEH
NSFFQQVVRGVIIVVAVLANILLTQRSSKAKR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503