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The map label for this gene is ompC [H]

Identifier: 157157896

GI number: 157157896

Start: 2497995

End: 2499086

Strand: Reverse

Name: ompC [H]

Synonym: EcE24377A_2514

Alternate gene names: 157157896

Gene position: 2499086-2497995 (Counterclockwise)

Preceding gene: 157156212

Following gene: 157156220

Centisome position: 50.19

GC content: 50.64

Gene sequence:

>1092_bases
ATGAAAGTTAAAGTACTGTCCCTCCTGGTCCCAGCTCTGCTGGTAGCAGGCGCAGCAAACGCTGCTGAAGTTTACAACAA
AGACGGCAACAAATTAGATCTGTACGGTAAAGTAGACGGCCTGCACTATTTCTCTGACAACAAAGATGTAGATGGCGACC
AGACCTACATGCGTCTTGGCTTCAAAGGTGAAACTCAGGTTACTGACCAGCTGACCGGTTACGGCCAGTGGGAATATCAG
ATCCAGGGCAACAGCGCTGAAAACGAAAACAACTCCTGGACCCGTGTGGCATTCGCAGGTCTGAAATTCCAGGATGTAGG
TTCTTTCGACTACGGTCGTAACTACGGCGTTGTTTACGACGTAACTTCCTGGACCGACGTACTGCCAGAATTCGGTGGCG
ACACTTACGGTTCTGACAACTTCATGCAGCAGCGTGGTAACGGTTTCGCGACCTACCGTAACACTGACTTCTTCGGTCTG
GTTGACGGCCTGAACTTTGCTGTTCAGTACCAGGGCAAAAACGGTAGCGTAAGCGGCGAAGGCATGACTAACAACGGTCG
TGAAGCACTGCGTCAGAACGGCGACGGCGTTGGCGGATCTATCACTTATGATTACGAAGGCTTCGGTATCGGTGCTGCAG
TTTCCAGCTCCAAACGTACTGATGATCAGAACAGCCCGCTGTACATCGGTAACGGCGACCGTGCTGAAACCTACACTGGT
GGTCTGAAATACGACGCTAACAACATCTACCTGGCTGCTCAGTACACCCAGACCTACAACGCAACTCGCGTAGGTTCCCT
GGGTTGGGCGAACAAAGCACAGAACTTCGAAGCTGTTGCTCAGTACCAGTTCGACTTTGGTCTGCGTCCGTCCCTGGCTT
ACCTGCAGTCTAAAGGTAAAAACCTGGGTCGTGGCTACGACGACGAAGATATCCTGAAATATGTTGATGTTGGTGCGACC
TACTACTTCAACAAAAACATGTCCACCTATGTTGACTACAAAATCAACCTGCTGGACGACAACCAGTTCACTCGTGACGC
TGGCATCAACACTGATAACATCGTAGCTCTGGGTCTGGTTTACCAGTTCTAA

Upstream 100 bases:

>100_bases
ATTTTTGGGGAGAATGGACTTGCCGACTGATTAATGAGGGTTAATCAGTATGCAGTGGCATAAAAAAGCAAATAAAGGCA
TATAACAGAGGGTTAATAAC

Downstream 100 bases:

>100_bases
TCTCGATTGATATCGAACAAAGGGCCTGCGGGCCCTTTTTTCATTGTTTTCAGCGTACAAACACAGTTTTTTGGTGTACT
CTTGCGACCGTTCGCATGAG

Product: outer membrane porin protein C

Products: NA

Alternate protein names: Outer membrane protein 1B; Porin ompC [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAVQYQGKNGSVSGEGMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNSPLYIGNGDRAETYTG
GLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGAT
YYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

Sequences:

>Translated_363_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAVQYQGKNGSVSGEGMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNSPLYIGNGDRAETYTG
GLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGAT
YYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF
>Mature_363_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAVQYQGKNGSVSGEGMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNSPLYIGNGDRAETYTG
GLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGAT
YYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

Specific function: Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

Organism=Escherichia coli, GI1788544, Length=367, Percent_Identity=96.1852861035422, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI1787641, Length=378, Percent_Identity=67.4603174603175, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1786436, Length=368, Percent_Identity=58.1521739130435, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1787160, Length=378, Percent_Identity=59.7883597883598, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: 6020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 19068 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001897
- InterPro:   IPR013793
- InterPro:   IPR001702 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 40095; Mature: 40095

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEC
FKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYD
CCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGKNGSVSGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCCC
GMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNSPLYIGNGDRAETYTG
CCCCCCHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCEEEECCCCCCEEEC
GLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGK
CEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCCC
NLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLV
CCCCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEE
YQF
ECC
>Mature Secondary Structure
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEC
FKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYD
CCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGKNGSVSGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCCC
GMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNSPLYIGNGDRAETYTG
CCCCCCHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCEEEECCCCCCEEEC
GLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGK
CEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCCC
NLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLV
CCCCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEE
YQF
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]