BacMap

Definition	Escherichia coli E24377A, complete genome.
Accession	NC_009801
Length	4,979,619

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The map label for this gene is yjgI

Identifier: 157157825

GI number: 157157825

Start: 4813898

End: 4814611

Strand: Reverse

Name: yjgI

Synonym: EcE24377A_4821

Alternate gene names: 157157825

Gene position: 4814611-4813898 (Counterclockwise)

Preceding gene: 157155943

Following gene: 157157785

Centisome position: 96.69

GC content: 54.34

Gene sequence:

>714_bases
ATGGGCGCTTTTACAGGTAAGACAGTTCTCATCCTCGGTGGCAGTCGTGGTATCGGTGCCGCTATCGTACGTCGTTTCGT
CACCGATGGGGCCAATGTACGATTCACCTATGCGGGGTCGAAAGATGCCGCTAAACGCCTGGCACAAGAGACTGGAGCGA
CAGCAGTATTCACAGATAGTGCTGACAGAGACGCTGTCATTGATGTCGTTCGTAAGAGCGGCGCATTGGATATCCTGGTG
GTAAATGCAGGTATTGGCGTCTTTGGCGAGGCCCTGGAATTAAATGCCGACGATATTGATCGCCTTTTCAAAATCAATAT
TCATGCTCCTTATCATGCCTCTGTTGAAGCCGCCCGGCAGATGCCCGAAGGCGGGCGCATCTTAATCATCGGCTCCGTGA
ATGGCGATCGTATGCCTGTTGCAGGCATGGCTGCTTATGCCGCCAGCAAATCTGCCCTGCAAGGCATGGCGCGCGGGCTG
GCCCGTGATTTTGGACCGCGTGGGATCACCATTAACGTCGTCCAGCCAGGGCCAATTGATACCGACGCTAATCCCGCCAA
CGGGCCAATGCGCGATATGTTGCATAGTTTGATGGCTATCAAAAGACATGGGCAACCGGAAGAGGTCGCTGGTATGGTCG
CATGGTTAGCAGGGCCAGAAGCCAGTTTTGTTACCGGCGCGATGCATACCATTGATGGCGCGTTTGGCGCATAA

Upstream 100 bases:

>100_bases
TGGAACGCGAGATTGTTTTTTAGTGACCATTACAAAACCTGTTGACAGAAAGTTAAAACAGTTTTGTAATGCATGTTACA
TAATAAATCAAGGAGTCCTT

Downstream 100 bases:

>100_bases
CCGACTACGCTCAATTAAGCCCAGCCATTATCCATGATGTCTGGGTTTTGTTTACTCACGTCGTCCGCTAAAAGCGGCTC
CCGGTAAAGAGAAATCTTCT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDSADRDAVIDVVRKSGALDILV
VNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA

Sequences:

>Translated_237_residues
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDSADRDAVIDVVRKSGALDILV
VNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
>Mature_236_residues
GAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDSADRDAVIDVVRKSGALDILVV
NAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLA
RDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=28.6885245901639, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=26.5560165975104, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI126723750, Length=240, Percent_Identity=27.5, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=26.2886597938144, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=25.3112033195021, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=28.4153005464481, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=28.3898305084746, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI66933014, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=27.0916334661355, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4503817, Length=228, Percent_Identity=27.1929824561404, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=30.952380952381, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI223718074, Length=215, Percent_Identity=28.8372093023256, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=100, Blast_Score=473, Evalue=1e-135,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.8582677165354, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=35.9832635983264, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=27.3092369477912, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=32.5102880658436, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=26.5060240963855, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=31.9502074688797, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=29.5546558704453, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=26.9387755102041, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789208, Length=176, Percent_Identity=28.9772727272727, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786701, Length=189, Percent_Identity=30.6878306878307, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=30.3149606299213, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.0322580645161, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=29.3877551020408, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=29.1497975708502, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=250, Percent_Identity=28.8, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=192, Percent_Identity=29.1666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=27.8625954198473, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=28.0155642023346, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=28.740157480315, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=26.8595041322314, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=28.0769230769231, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=250, Percent_Identity=27.6, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=195, Percent_Identity=29.7435897435897, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=26.0536398467433, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=192, Percent_Identity=27.0833333333333, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=27.3076923076923, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=25.1851851851852, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=26.2357414448669, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=26.6917293233083, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=34.2741935483871, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=30.5785123966942, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=30.8641975308642, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=30.9236947791165, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=28.2157676348548, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=29.6442687747036, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=28.8, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=32.1637426900585, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641232, Length=221, Percent_Identity=29.8642533936652, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YJGI_ECOLI (P39333)

Other databases:

- EMBL:   U14003
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D65237
- RefSeq:   AP_004746.1
- RefSeq:   NP_418670.1
- ProteinModelPortal:   P39333
- SMR:   P39333
- DIP:   DIP-12604N
- IntAct:   P39333
- STRING:   P39333
- EnsemblBacteria:   EBESCT00000000511
- EnsemblBacteria:   EBESCT00000017295
- GeneID:   948765
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW4207
- KEGG:   eco:b4249
- EchoBASE:   EB2418
- EcoGene:   EG12528
- eggNOG:   COG1028
- GeneTree:   EBGT00050000009180
- HOGENOM:   HBG750976
- OMA:   PVIDITT
- ProtClustDB:   PRK12742
- BioCyc:   EcoCyc:G7880-MONOMER
- Genevestigator:   P39333
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081
- PRINTS:   PR00080

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24598; Mature: 24467

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 146-146 BINDING 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDS
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCEEEEECC
ADRDAVIDVVRKSGALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQ
CCCHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCHHHCCEEEEEEECCCCCCHHHHHHC
MPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPID
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
TDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDS
CCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCEEEEECC
ADRDAVIDVVRKSGALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQ
CCCHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCHHHCCEEEEEEECCCCCCHHHHHHC
MPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPID
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
TDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503