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The map label for this gene is hokA [H]

Identifier: 157157721

GI number: 157157721

Start: 4034559

End: 4034711

Strand: Reverse

Name: hokA [H]

Synonym: EcE24377A_4053

Alternate gene names: 157157721

Gene position: 4034711-4034559 (Counterclockwise)

Preceding gene: 157156177

Following gene: 157158777

Centisome position: 81.02

GC content: 34.64

Gene sequence:

>153_bases
ATGCCGCAGAAATATAGATTACTTTCTTTAATAGTGATTTGTTTCACGCTTTTATTTTTCACCTGGATGATAAGAGATTC
ACTGTGTGAATTGCATATTAAACAGGGGAGTTATGAGCTGGCGGCATTTTTAGCCTGCAATTTAAAAGAGTAA

Upstream 100 bases:

>100_bases
AAAAGCCCCACCTGACTATAAATCAAAGTGAGGCTACCCTATGCCTGAACACCATAAGGTTAGCCTCTTACTCGTTGGAA
ATCAACACAGGGGGCTGGGA

Downstream 100 bases:

>100_bases
GAGTCTTCGGCGGGAAGTTATTCCCGCCTTTCTTACGGCGTTGCGCATTCTCATTGCACCCAAATTTATTTTTCACAAAA
ATAATACTAGATTTTATTAC

Product: small toxic polypeptide

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 50; Mature: 49

Protein sequence:

>50_residues
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLACNLKE

Sequences:

>Translated_50_residues
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLACNLKE
>Mature_49_residues
PQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLACNLKE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family [H]

Homologues:

Organism=Escherichia coli, GI48994947, Length=50, Percent_Identity=96, Blast_Score=99, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000021
- InterPro:   IPR018084
- ProDom:   PD005979 [H]

Pfam domain/function: PF01848 HOK_GEF [H]

EC number: NA

Molecular weight: Translated: 5912; Mature: 5781

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
10.0 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLACNLKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
PQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLACNLKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2404279; 8041620; 9278503; 7940673; 7984428; 10361310 [H]