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The map label for this gene is mdoC

Identifier: 157156321

GI number: 157156321

Start: 1185248

End: 1186405

Strand: Reverse

Name: mdoC

Synonym: EcE24377A_1167

Alternate gene names: 157156321

Gene position: 1186405-1185248 (Counterclockwise)

Preceding gene: 157155624

Following gene: 157155137

Centisome position: 23.83

GC content: 43.87

Gene sequence:

>1158_bases
ATGAATCCAGTACCCGCGCAACGTGAATATTTCCTCGACTCCATCCGCGCCTGGCTGATGTTGTTAGGGATCCCTTTTCA
TATTTCTTTAATCTATTCGAGCCATACATGGCATGTGAATAGCGCCGAACCGTCATTGTGGCTGACCCTTTTTAATGACT
TCATCCACTCGTTCCGCATGCAGGTATTTTTCGTTATATCCGGCTACTTTTCCTACATGCTTTTTTTACGCTATCCCTTG
AAAAAATGGTGGAAAGTACGTGTCGAACGTGTAGGTATCCCGATGTTAACAGCCATCCCCCTACTGACATTGCCGCAATT
TATTATGCTGCAATACGTCAAAGGGAAAGCGGAAAGTTGGCCTGGGCTGTCATTGTATGACAAATATAATACGTTGGCCT
GGGAATTAATATCACACCTGTGGTTTTTACTGGTGTTAGTAGTCATGACGACGCTGTGCGTATGGATATTTAAACGCATC
AGAAATAATTTAGAAAATTCTGATAAAACGAATAAAAAATTCTCGATGGTAAAACTATCGGTGATTTTTTTATGCCTCGG
CATCGGCTATGCGGTAATAAGAAGAACGATTTTTATTGTGTATCCGCCCATTCTGAGTAATGGCATGTTCAATTTTATTG
TCATGCAAACGCTATTTTATTTGCCGTTCTTTATCCTCGGTGCACTGGCTTTCATTTTCCCTCATCATAAAGCCTTGTTT
ACCACGCCGTCTCGTGGCTGTACCCTTGCAGCAGCATTGGCATTTGTCGCTTATTTACTCAACCAGCGCTATGGCAGTGG
CGATGCCTGGATGTACGAAACCGAGTCGGTGATCACCATGGTCCTCGGTCTGTGGATGGTGAATGTGGTCTTCTCCTTTG
GCCACCGTTTGCTTAACTTCCAGTCAGCGCGGGTGACTTACTTTGTTAACGCATCGCTATTTATCTATCTGGTTCACCAC
CCGTTAACGCTGTTTTTCGGCGCATACATTACACCGCACATCACCTCCAACTGGCTTGGTTTTCTCTGTGGCCTGATATT
CGTAGTAGGGATTGCGATAATTCTGTATGAAATTCATTTACGCATCCCGTTACTGAAGTTTTTGTTTTCTGGTAAACCGG
TTGTTAAGCGTGAGAACGATAAAGCACCAGCCCGTTAA

Upstream 100 bases:

>100_bases
CCTGCGCCTGGCGCGGTCAGGTCGGTGTCGCTATGGCAACAAGCCTAAAGGCATAACCCGACAGGGATAAGACGAAAAAT
CCGAGATTAGTTAACCATAT

Downstream 100 bases:

>100_bases
GCCACATTTACAATAACCATTCCACGGGCAATATCGACGCCAGTCTGACCATAACCCGCTTCCAGAAACTGGTGGCGGGT
TCTTTTTTGAGAATAATCTC

Product: glucans biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPL
KKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHHKALF
TTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHH
PLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR

Sequences:

>Translated_385_residues
MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPL
KKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHHKALF
TTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHH
PLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
>Mature_385_residues
MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPL
KKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHHKALF
TTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHH
PLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR

Specific function: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family. OpgC subfamily

Homologues:

Organism=Escherichia coli, GI1787285, Length=385, Percent_Identity=99.4805194805195, Blast_Score=775, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OPGC_ECO24 (A7ZKF0)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001462279.1
- STRING:   A7ZKF0
- EnsemblBacteria:   EBESCT00000022879
- GeneID:   5586057
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_1167
- NMPDR:   fig|331111.3.peg.3645
- eggNOG:   NOG07527
- GeneTree:   EBGT00050000010615
- HOGENOM:   HBG416347
- OMA:   FNFVVMQ
- ProtClustDB:   PRK03854
- BioCyc:   ECOL331111:ECE24377A_1167-MONOMER
- HAMAP:   MF_01066
- InterPro:   IPR002656

Pfam domain/function: PF01757 Acyl_transf_3

EC number: 2.1.-.- [C]

Molecular weight: Translated: 44725; Mature: 44725

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1bda1afc)-; HASH(0x1bf08da4)-; HASH(0x1c58d1d4)-; HASH(0x1b828350)-; HASH(0x1cdd65a4)-; HASH(0x1c9c5f94)-; HASH(0x1cdb4688)-; HASH(0x1cddb2cc)-; HASH(0x1cdba9b8)-; HASH(0x1cdd57d8)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCEECCCCCCCCH
>Mature Secondary Structure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HHHHHHHHHCCCCCEECCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA