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The map label for this gene is infC [H]

Identifier: 157156228

GI number: 157156228

Start: 1925917

End: 1926351

Strand: Reverse

Name: infC [H]

Synonym: EcE24377A_1936

Alternate gene names: 157156228

Gene position: 1926351-1925917 (Counterclockwise)

Preceding gene: 157158126

Following gene: 157155376

Centisome position: 38.68

GC content: 47.82

Gene sequence:

>435_bases
GTGAGTCTGAGAGAAGCTCTGGAGAAAGCAGAAGAAGCCGGAGTAGACTTAGTCGAGATCAGCCCTAACGCCGAGCCGCC
GGTTTGTCGTATAATGGATTACGGCAAATTCCTCTATGAAAAGAGCAAGTCTTCTAAGGAACAGAAGAAAAAGCAAAAAG
TTATCCAGGTTAAGGAAATTAAATTCCGTCCTGGTACAGATGAAGGCGACTATCAGGTAAAACTCCGCAGCCTGATTCGC
TTTCTCGAAGAGGGTGATAAAGCCAAAATCACGCTGCGTTTCCGCGGTCGTGAGATGGCGCACCAGCAAATCGGTATGGA
AGTGCTTAATCGCGTGAAAGACGATTTGCAAGAACTGGCAGTGGTCGAATCCTTCCCAACGAAGATCGAAGGCCGCCAGA
TGATCATGGTGCTCGCTCCTAAGAAGAAACAGTAA

Upstream 100 bases:

>100_bases
CGGAAAACGAGTTCAAACGGCGCGCCCTAACCGTATCAATGGCGAAATTCGCGCCCAGGAAGTTCGCTTAACAGGTCTGG
AAGGCGAGCAGCTTGGTATT

Downstream 100 bases:

>100_bases
GGCCTTCAAGTAGCACTGTCTGTGGAGCCTTCGGGCTTCACAGGCTTTGTTCGCCTTTGTTTCGTTTATTAACAATGCGA
AGTGGAAGTTATTAAAATGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIR
FLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVESFPTKIEGRQMIMVLAPKKKQ

Sequences:

>Translated_144_residues
MSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIR
FLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVESFPTKIEGRQMIMVLAPKKKQ
>Mature_143_residues
SLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRF
LEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVESFPTKIEGRQMIMVLAPKKKQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=144, Percent_Identity=99.3055555555556, Blast_Score=288, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 16638; Mature: 16506

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEI
CCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHE
KFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELA
EECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VVESFPTKIEGRQMIMVLAPKKKQ
HHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEI
CHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHE
KFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELA
EECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VVESFPTKIEGRQMIMVLAPKKKQ
HHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA