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The map label for this gene is hipB [H]

Identifier: 157156109

GI number: 157156109

Start: 1709802

End: 1710086

Strand: Reverse

Name: hipB [H]

Synonym: EcE24377A_1709

Alternate gene names: 157156109

Gene position: 1710086-1709802 (Counterclockwise)

Preceding gene: 157155821

Following gene: 157156577

Centisome position: 34.34

GC content: 44.21

Gene sequence:

>285_bases
TTGCTGTGGACGTATGACATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTAGCGAATGCAATGAAACTGGTTCG
CCAGCAAAATGGCTGGACGCAGAGCGAGCTGGCGAAAAAAATTGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACA
ACCCTGACAATACCACGCTCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACACTATGCGACACGAAA
AATGCCTCGCCAGAATCAACAGAACAGCAAGATCTGGAGTGGTAA

Upstream 100 bases:

>100_bases
ATCGCAGCGTTTATCCCGTACAGCGGATAAGATGTGTTTCCAGATTGACTTTATCCTCACTAAAGGATAAAACTGATAAT
ATCCCCTTAAGCGGATAAAT

Downstream 100 bases:

>100_bases
TGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAAG
TATGCACCGGAGTGGTTAGC

Product: DNA-binding transcriptional regulator HipB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDTK
NASPESTEQQDLEW

Sequences:

>Translated_94_residues
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDTK
NASPESTEQQDLEW
>Mature_94_residues
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDTK
NASPESTEQQDLEW

Specific function: Binds to operator sites with the consensus sequence 5-'TATCCN(8)GGATA-3' and repress the hip operon promoter [H]

COG id: COG1396

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787786, Length=88, Percent_Identity=97.7272727272727, Blast_Score=176, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982 [H]

Pfam domain/function: PF01381 HTH_3 [H]

EC number: NA

Molecular weight: Translated: 10857; Mature: 10857

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTL
CCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHH
TTFFKILQSLELSMTLCDTKNASPESTEQQDLEW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTL
CCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHH
TTFFKILQSLELSMTLCDTKNASPESTEQQDLEW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1715862; 9097039; 9278503; 8021189 [H]