BacMap

Definition	Escherichia coli E24377A, complete genome.
Accession	NC_009801
Length	4,979,619

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The map label for this gene is astD

Identifier: 157156088

GI number: 157156088

Start: 1953878

End: 1955356

Strand: Reverse

Name: astD

Synonym: EcE24377A_1968

Alternate gene names: 157156088

Gene position: 1955356-1953878 (Counterclockwise)

Preceding gene: 157157503

Following gene: 157155531

Centisome position: 39.27

GC content: 57.74

Gene sequence:

>1479_bases
ATGACTTTATGGATTAACGGTGACTGGATAACGGGCCAGGGCGCATCGCGTGTGAAGCGTAATCCGGTATCGGGCGAGGT
GTTATGGCAAGGCAATGATGCCGATGCCGCTCAGGTCGGGCAGGCTTGTCGCGCAGCCCGTGCGGCGTTTCCGCGCTGGG
CGCGGCTCTCATTGGCTGAACGTCAGGTCGTTGTCGAACGCTTTGCCGGATTGCTGGAAAGGAATAAAGGCGAATTAACC
GCGATTATTGCCAGAGAAACGGGTAAGCCGCGCTGGGAAGCGGCAACCGAAGTGACGGCGATGATCAATAAAATCGCGAT
ATCAATTAAGGCGTATCACGTTCGTACCGGCGAGCAACGTAGTGAAATGCCGGACGGTGCGGCGAGCCTGCGACATCGCC
CGCACGGCGTGCTGGCGGTGTTTGGGCCGTATAATTTCCCTGGTCATTTGCCGAACGGACATATCGTTCCGGCATTGTTG
GCAGGTAACACCATTATCTTTAAACCCAGCGAACTGACACCGTGGAGTGGCGAAGCGGTAATGCGTTTATGGCAGCAGGC
TGGCTTGCCGCCGGGCGTACTGAACCTGGTGCAGGGCGGGCGTGAAACGGGTCAGGCGCTGAGTGCGCTGGAGGATCTCG
ACGGTTTGCTGTTTACCGGTAGCGCCAATACCGGCTACCAGCTGCATCGCCAGCTCTCCGGTCAGCCGGAGAAAATTCTC
GCCCTTGAGATGGGCGGTAATAATCCGCTAATTATCGATGAGGTGGCGGATATCGACGCGGCTGTCCATCTGACCATTCA
GTCGGCGTTTGTCACAGCCGGGCAACGCTGCACCTGCGCCCGCCGTTTATTGCTCAAAAGCGGAGCGCAGGGCGATGCGT
TTCTTGCTCGTCTGGTTGCCGTCAGCCAGCGATTAACGCCGGGCAACTGGGATGACGAACCGCAGCCGTTTATTGGCGGG
CTGATTTCTGAACAGGCCGCACAGCAGGTGGTTACTGCCTGGCAGCAACTGGAAGCGATGGGCGGACGAACCCTGCTTGC
GCCGCGCTTATTACAATCAGAGACATCGTTGCTGACGCCGGGGATCATTGAAATGACAGGCGTTGCTGGCGTACCAGATG
AAGAGGTGTTCGGACCGTTATTGCGCGTCTGGCGTTATGATTCTTTCGAGGAAGCGATTCTAATGGCGAATAACACTCGC
TTCGGACTCTCTTGCGGTCTGGTTTCCCCCGAGCGGGAAAAATTCGATCAACTGTTGCTGGAGGCGCGGGCGGGGATTGT
TAACTGGAACAAACCGCTTACTGGTGCTGCCAGTACCGCGCCATTCGGCGGCATTGGTGCATCCGGTAACCATCGCCCCA
GCGCCTGGTATGCCGCAGATTACTGCGCATGGCCTATGGCGAGCCTGGAGTCGGACTCGTTAACTTTGCCCGCAACGCTT
AACCCCGGGCTGGATTTTTCCGATGAGGTGGTGCGATGA

Upstream 100 bases:

>100_bases
CCGAGCGTTTGATTTTAACCGCCGCACAACTGGATGCCCTCAAATGCCACGCAGGGGATCGCGTTCGTCTGGTGCGCCTG
TGCGCAGAGGAGAAAACAGC

Downstream 100 bases:

>100_bases
ACGCCTGGGAAGTTAATTTCGACGGGCTGGTAGGGCTGACGCATCATTACGCCGGCCTGTCGTTTGGTAATGAAGCCTCT
ACCTGTCACCGTTTTCAGGT

Product: succinylglutamic semialdehyde dehydrogenase

Products: NA

Alternate protein names: Succinylglutamic semialdehyde dehydrogenase; SGSD

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSLAERQVVVERFAGLLERNKGELT
AIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKIL
ALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGG
LISEQAAQQVVTAWQQLEAMGGRTLLAPRLLQSETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAILMANNTR
FGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATL
NPGLDFSDEVVR

Sequences:

>Translated_492_residues
MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSLAERQVVVERFAGLLERNKGELT
AIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKIL
ALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGG
LISEQAAQQVVTAWQQLEAMGGRTLLAPRLLQSETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAILMANNTR
FGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATL
NPGLDFSDEVVR
>Mature_491_residues
TLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSLAERQVVVERFAGLLERNKGELTA
IIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLA
GNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILA
LEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGL
ISEQAAQQVVTAWQQLEAMGGRTLLAPRLLQSETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAILMANNTRF
GLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATLN
PGLDFSDEVVR

Specific function: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. AstD subfamily

Homologues:

Organism=Homo sapiens, GI153266822, Length=474, Percent_Identity=28.9029535864979, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI12007648, Length=453, Percent_Identity=31.1258278145695, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI25777730, Length=472, Percent_Identity=29.8728813559322, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI25777724, Length=463, Percent_Identity=29.5896328293737, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI25777732, Length=469, Percent_Identity=28.3582089552239, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI21361176, Length=469, Percent_Identity=29.637526652452, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI115387104, Length=461, Percent_Identity=28.1995661605206, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI4507229, Length=464, Percent_Identity=30.3879310344828, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI25777721, Length=477, Percent_Identity=29.559748427673, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI21614513, Length=470, Percent_Identity=29.5744680851064, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI25777728, Length=405, Percent_Identity=28.8888888888889, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI25952152, Length=445, Percent_Identity=28.7640449438202, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI238814322, Length=470, Percent_Identity=28.5106382978723, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI11095441, Length=409, Percent_Identity=27.3838630806846, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI310128093, Length=458, Percent_Identity=27.0742358078603, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310128103, Length=458, Percent_Identity=26.8558951965066, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI188035924, Length=458, Percent_Identity=26.8558951965066, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI25777726, Length=462, Percent_Identity=27.0562770562771, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI310128091, Length=458, Percent_Identity=26.2008733624454, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI238859541, Length=438, Percent_Identity=27.6255707762557, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI25777736, Length=438, Percent_Identity=27.6255707762557, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI25777734, Length=438, Percent_Identity=27.6255707762557, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI310128089, Length=279, Percent_Identity=30.1075268817204, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI4502043, Length=444, Percent_Identity=25, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI238814371, Length=444, Percent_Identity=25, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI206597441, Length=421, Percent_Identity=25.8907363420428, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI206597439, Length=421, Percent_Identity=25.8907363420428, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI22907049, Length=421, Percent_Identity=25.8907363420428, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI301500698, Length=276, Percent_Identity=30.4347826086957, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI310128095, Length=309, Percent_Identity=28.4789644012945, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI73695881, Length=334, Percent_Identity=26.6467065868263, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI73695879, Length=334, Percent_Identity=26.6467065868263, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI71773324, Length=349, Percent_Identity=26.0744985673352, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI310128097, Length=253, Percent_Identity=31.2252964426877, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI310128087, Length=285, Percent_Identity=27.3684210526316, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI4557303, Length=325, Percent_Identity=24.6153846153846, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI73466520, Length=326, Percent_Identity=23.9263803680982, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI223972651, Length=497, Percent_Identity=24.748490945674, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788042, Length=492, Percent_Identity=97.3577235772358, Blast_Score=973, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=467, Percent_Identity=31.4775160599572, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1787558, Length=462, Percent_Identity=32.4675324675325, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1787684, Length=411, Percent_Identity=29.9270072992701, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786504, Length=462, Percent_Identity=28.1385281385281, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1787250, Length=437, Percent_Identity=31.1212814645309, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI1787715, Length=476, Percent_Identity=28.3613445378151, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081896, Length=468, Percent_Identity=29.7008547008547, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87082295, Length=467, Percent_Identity=28.4796573875803, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI87081926, Length=455, Percent_Identity=25.2747252747253, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787653, Length=328, Percent_Identity=25.609756097561, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144435, Length=479, Percent_Identity=30.4801670146138, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17562198, Length=468, Percent_Identity=29.4871794871795, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI25143874, Length=443, Percent_Identity=30.0225733634311, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI25143876, Length=443, Percent_Identity=30.0225733634311, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17551164, Length=449, Percent_Identity=28.7305122494432, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=422, Percent_Identity=30.3317535545024, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17534119, Length=461, Percent_Identity=27.114967462039, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI71995606, Length=442, Percent_Identity=28.2805429864253, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI133930964, Length=470, Percent_Identity=28.0851063829787, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI115534176, Length=424, Percent_Identity=29.2452830188679, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71995613, Length=399, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71986308, Length=447, Percent_Identity=25.7270693512304, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17564084, Length=433, Percent_Identity=22.8637413394919, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17534447, Length=340, Percent_Identity=27.0588235294118, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115532534, Length=336, Percent_Identity=26.7857142857143, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32564151, Length=295, Percent_Identity=26.7796610169492, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71990744, Length=157, Percent_Identity=30.5732484076433, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319478, Length=472, Percent_Identity=29.0254237288136, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6320917, Length=465, Percent_Identity=29.247311827957, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6323821, Length=483, Percent_Identity=28.7784679089027, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323822, Length=475, Percent_Identity=29.0526315789474, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6324950, Length=458, Percent_Identity=26.8558951965066, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6325196, Length=456, Percent_Identity=26.5350877192982, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6321826, Length=489, Percent_Identity=28.2208588957055, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321828, Length=463, Percent_Identity=21.3822894168467, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=414, Percent_Identity=24.8792270531401, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281362580, Length=468, Percent_Identity=30.3418803418803, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI62472918, Length=468, Percent_Identity=30.3418803418803, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI62472926, Length=468, Percent_Identity=30.3418803418803, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI62472936, Length=468, Percent_Identity=30.3418803418803, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21356737, Length=468, Percent_Identity=30.3418803418803, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI20129399, Length=476, Percent_Identity=29.6218487394958, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24650465, Length=460, Percent_Identity=28.4782608695652, Blast_Score=168, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24666674, Length=474, Percent_Identity=27.6371308016878, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24585660, Length=466, Percent_Identity=28.3261802575107, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24638878, Length=459, Percent_Identity=25.4901960784314, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638876, Length=459, Percent_Identity=25.4901960784314, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24668425, Length=447, Percent_Identity=26.8456375838926, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24668417, Length=447, Percent_Identity=26.8456375838926, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24668413, Length=447, Percent_Identity=26.8456375838926, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28574525, Length=442, Percent_Identity=26.2443438914027, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI281360299, Length=448, Percent_Identity=22.3214285714286, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360297, Length=448, Percent_Identity=22.3214285714286, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360295, Length=448, Percent_Identity=22.3214285714286, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586250, Length=448, Percent_Identity=22.3214285714286, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360301, Length=448, Percent_Identity=22.3214285714286, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45552499, Length=448, Percent_Identity=21.875, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281360303, Length=448, Percent_Identity=21.875, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571798, Length=417, Percent_Identity=23.7410071942446, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571796, Length=417, Percent_Identity=23.7410071942446, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571794, Length=417, Percent_Identity=23.7410071942446, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571806, Length=417, Percent_Identity=23.7410071942446, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28571802, Length=417, Percent_Identity=23.7410071942446, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28571800, Length=417, Percent_Identity=23.7410071942446, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTD_ECO24 (A7ZML4)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001463043.1
- ProteinModelPortal:   A7ZML4
- SMR:   A7ZML4
- STRING:   A7ZML4
- EnsemblBacteria:   EBESCT00000022567
- GeneID:   5586005
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_1968
- eggNOG:   COG1012
- GeneTree:   EBGT00050000009176
- HOGENOM:   HBG752218
- OMA:   KAYHART
- ProtClustDB:   PRK09457
- BioCyc:   ECOL331111:ECE24377A_1968-MONOMER
- HAMAP:   MF_01174
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017649
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699
- TIGRFAMs:   TIGR03240

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.71

Molecular weight: Translated: 53030; Mature: 52899

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 243-243 ACT_SITE 277-277

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSLAE
CEEEEECCEEECCCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
RQVVVERFAGLLERNKGELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQR
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCHH
SEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAV
HCCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEHEECCCEEEECCCCCCCCCCHHH
MRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKIL
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCEEE
ALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVA
EEEECCCCCEEEECCCCCCEEEEEEEEHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
VSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAWQQLEAMGGRTLLAPRLLQSETSLLTP
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHCCHHHCCC
GIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAILMANNTRFGLSCGLVSPEREKFDQLLL
CHHEECCCCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCEEEEECCCCCHHHHHHHHHH
EARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATL
HHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCCCCCCEEECEEC
NPGLDFSDEVVR
CCCCCCCHHHCC
>Mature Secondary Structure 
TLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSLAE
EEEEECCEEECCCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
RQVVVERFAGLLERNKGELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQR
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCHH
SEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAV
HCCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEHEECCCEEEECCCCCCCCCCHHH
MRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKIL
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCEEE
ALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVA
EEEECCCCCEEEECCCCCCEEEEEEEEHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
VSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAWQQLEAMGGRTLLAPRLLQSETSLLTP
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHCCHHHCCC
GIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAILMANNTRFGLSCGLVSPEREKFDQLLL
CHHEECCCCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCEEEEECCCCCHHHHHHHHHH
EARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATL
HHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCCCCCCEEECEEC
NPGLDFSDEVVR
CCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA