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The map label for this gene is qmcA [H]

Identifier: 157155972

GI number: 157155972

Start: 549801

End: 550718

Strand: Reverse

Name: qmcA [H]

Synonym: EcE24377A_0528

Alternate gene names: 157155972

Gene position: 550718-549801 (Counterclockwise)

Preceding gene: 157156452

Following gene: 157158261

Centisome position: 11.06

GC content: 52.72

Gene sequence:

>918_bases
ATGCTTATCTTTATCCCGATTCTCATTTTTGTCGCGCTGGTCATTGTCGGCGCGGGCGTCAAAATCGTGCCGCAGGGCTA
TCAATGGACGGTAGAACGTTTTGGTCGCTATACCAAAACGTTACAGCCGGGGCTCAGTCTGGTGGTGCCGTTTATGGATC
GCATTGGTCGCAAGATCAATATGATGGAGCAAGTGCTCGATATCCCTTCCCAGGAAGTTATCTCGAAAGATAACGCCAAC
GTTACCATCGACGCAGTCTGTTTTATTCAGGTGATTGACGCGCCGCGCGCGGCTTATGAAGTCAGCAATCTGGAGCTGGC
GATCATCAACCTGACCATGACTAACATCCGTACCGTGTTGGGTTCAATGGAACTTGACGAAATGCTCTCTCAGCGCGACA
GCATCAACTCACGCCTGCTGCGTATTGTCGATGAAGCCACCAACCCGTGGGGGATTAAAGTCACCCGTATTGAAATTCGC
GACGTGCGCCCACCGGCAGAGCTTATCTCTTCACTGAACGCGCAGATGAAAGCGGAACGTACCAAACGCGCTTACATTCT
TGAAGCGGAAGGGATCCGTCAGGCGGAAATCCTCAAAGCCGAAGGTGAAAAACAGTCGCAAATCCTGAAAGCGGAAGGCG
AACGTCAGTCGGCGTTTTTACAGGCTGAAGCGCGTGAACGTTCCGCCGAAGCAGAAGCCCGCGCCACCAAAATGGTGTCT
GAAGCTATCGCCTCCGGTGATATTCAGGCGGTGAACTACTTCGTAGCGCAGAAATACACCGAAGCGTTACAGCAGATCGG
TTCCTCCAGTAACAGCAAAGTAGTGATGATGCCATTAGAGGCCAGCAGCCTGATGGGGTCGATTGCCGGGATTGCCGAGC
TGGTGAAAGACAGCGCCAACAAACGGACTCAGCCATGA

Upstream 100 bases:

>100_bases
GCAGGAATAAGGGGGAACTCTCTTTCAGTAATCAGGTATAATTTGTTTAATCAAGCAGCAATTTTGCTGATTATGGACGG
TACAACAGGAGGTTTTTCCG

Downstream 100 bases:

>100_bases
TGGAGTTAATGGTCGTTCATCCACATATTTTCTGGCTCAGTCTCGGCGGTTTGCTGCTGGCAGCCGAGATGCTGGGCGGA
AATGGTTATTTGTTGTGGAG

Product: SPFH domain-containing protein/band 7 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
DVRPPAELISSLNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVS
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANKRTQP

Sequences:

>Translated_305_residues
MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
DVRPPAELISSLNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVS
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANKRTQP
>Mature_305_residues
MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
DVRPPAELISSLNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVS
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANKRTQP

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=264, Percent_Identity=34.469696969697, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI21686995, Length=193, Percent_Identity=34.1968911917098, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI221316744, Length=193, Percent_Identity=34.1968911917098, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI38016911, Length=192, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7657615, Length=138, Percent_Identity=35.5072463768116, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786697, Length=305, Percent_Identity=99.672131147541, Blast_Score=614, Evalue=1e-177,
Organism=Escherichia coli, GI1790616, Length=272, Percent_Identity=22.0588235294118, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32564147, Length=298, Percent_Identity=35.2348993288591, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17569493, Length=217, Percent_Identity=35.0230414746544, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI193209764, Length=217, Percent_Identity=35.0230414746544, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71989948, Length=155, Percent_Identity=36.1290322580645, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71989955, Length=155, Percent_Identity=36.1290322580645, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71987612, Length=198, Percent_Identity=33.8383838383838, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25153583, Length=192, Percent_Identity=34.375, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71987621, Length=218, Percent_Identity=33.0275229357798, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17569499, Length=193, Percent_Identity=33.6787564766839, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569497, Length=193, Percent_Identity=29.5336787564767, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17570459, Length=205, Percent_Identity=35.1219512195122, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566490, Length=188, Percent_Identity=32.9787234042553, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17570161, Length=195, Percent_Identity=33.8461538461538, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193210507, Length=195, Percent_Identity=33.8461538461538, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71989963, Length=120, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45550506, Length=275, Percent_Identity=35.6363636363636, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI45556022, Length=193, Percent_Identity=34.1968911917098, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI18860517, Length=199, Percent_Identity=31.1557788944724, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24657857, Length=199, Percent_Identity=34.6733668341709, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281365664, Length=197, Percent_Identity=32.48730964467, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI62484448, Length=199, Percent_Identity=34.6733668341709, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI62484274, Length=199, Percent_Identity=34.6733668341709, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356845, Length=191, Percent_Identity=27.2251308900524, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281361631, Length=189, Percent_Identity=28.042328042328, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281361633, Length=194, Percent_Identity=27.319587628866, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28573263, Length=198, Percent_Identity=25.7575757575758, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281361635, Length=131, Percent_Identity=27.4809160305344, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33726; Mature: 33726

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS01270 BAND_7

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKIN
CEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHH
MMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVL
HHHHHHCCCCHHHHCCCCCCEEEEHEEEEHHHCCCHHHEEECCCEEEEEEEEHHHHHHHH
GSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIRDVRPPAELISSLNAQMKAER
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
TKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVS
HHHEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSAN
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
KRTQP
CCCCC
>Mature Secondary Structure
MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKIN
CEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHH
MMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVL
HHHHHHCCCCHHHHCCCCCCEEEEHEEEEHHHCCCHHHEEECCCEEEEEEEEHHHHHHHH
GSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIRDVRPPAELISSLNAQMKAER
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
TKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVS
HHHEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSAN
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
KRTQP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]