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The map label for this gene is yjjL [H]

Identifier: 157155947

GI number: 157155947

Start: 4932702

End: 4934063

Strand: Reverse

Name: yjjL [H]

Synonym: EcE24377A_4948

Alternate gene names: 157155947

Gene position: 4934063-4932702 (Counterclockwise)

Preceding gene: 157156458

Following gene: 157154876

Centisome position: 99.09

GC content: 52.35

Gene sequence:

>1362_bases
GTGGAAAAAGAAAATATCACCCTCGATCCGCGTTCTTCATTTACTCCATCTTCGTCGGCAGATATTCCCGTGCCACCAGA
TGGATTAGTTCAACGCAGTACCCGAATTAAACGCATTCAAACCACCGCCATGTTGTTATTATTTTTTGCGGCGGTAATCA
ATTATCTCGACCGCAGTTCGCTGTCGGTAGCAAATTTAACGATTCGTGAAGAATTGGGATTAAGTGCCACCGAAATCGGC
GCTTTGCTCTCCGTGTTTTCACTCGCTTACGGGATTGCGCAACTTCCTTGCGGCCCACTATTGGATCGTAAAGGCCCACG
CCTGATGCTGGGACTGGGGATGTTCTTCTGGTCACTGTTCCAGGCCATGTCTGGCATGGTGCACAGCTTTACGCAGTTCG
TGTTGGTGCGTATCGGTATGGGGATTGGTGAAGCGCCGATGAACCCATGTGGCGTAAAAGTCATTAACGACTGGTTCAAC
ATCAAAGAGCGCGGACGCCCGATGGGCTTCTTCAACGCAGCTTCTACCATTGGCGTTGCCGTAAGCCCACCGATTCTGGC
GGCGATGATGCTGGTGATGGGCTGGCGTGGGATGTTTATTACCATTGGTGTGCTGGGGATTTTTCTCGCCATTGGCTGGT
ATATGCTCTATCGCAACCGCGAGCACGTAGAACTGACTGCCGTTGAACAAGCTTATCTCAATGCAGGTAGCGTCAATGCC
CGCCGAGATCCGCTCAGTTTTGCCGAATGGCGCAGCCTGTTCCGTAACCGCACAATGTGGGGAATGATGCTCGGATTCAG
TGGCATCAACTACACTGCGTGGCTGTATCTGGCCTGGCTTCCTGGTTACCTGCAAACAGCCTATAACCTGGATTTAAAAA
GCACAGGGTTGATGGCGGCTATCCCTTTCCTGTTTGGGGCTGCCGGGATGCTGGTCAACGGTTACGTTACTGACTGGCTG
GTCAAAGGGGGAATGGCTCCGATTAAAAGCCGTAAGATCTGCATTATTGCCGGGATGTTCTGTTCTGCCGCCTTTACGCT
GGTCGTACCGCAAGCGACAACATCCATGACGGCGGTTCTGCTGATTGGCATGGCACTGTTCTGTATTCACTTTGCCGGAA
CATCCTGCTGGGGCTTGATCCACGTCGCAGTTGCTTCTCGCATGACGGCGTCGGTGGGCAGTATCCAGAACTTTGCCAGC
TTCATCTGCGCCTCTTTTGCGCCGATCATTACTGGTTTTATTGTTGATACCACCCACTCATTCCGTCTGGCACTAATCAT
CTGCGGTTGCGTCACCGCAGCGGGAGCACTGGCGTACATCTTCCTGGTTCGTCAGCCGATCAACGACCCGCGTAAAGATT
AA

Upstream 100 bases:

>100_bases
AGCGGTAGTAAAGTCCTAAAACTTTAACCTGCCGTTAATGTCAACCTTGCGTAATGCACAATTACGTAAACAATTAAAAT
TATAAATACAGGAGTCCGGC

Downstream 100 bases:

>100_bases
ACTCCCTATGCCCGATAACATTTTGCTTATCGGGCATTTTTATGGCGATTAAAACGTTTCCCAGTTCTCCCCGCTATCTG
CCACTGCCATTTTACGCGGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIG
ALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWL
VKGGMAPIKSRKICIIAGMFCSAAFTLVVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFAS
FICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD

Sequences:

>Translated_453_residues
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIG
ALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWL
VKGGMAPIKSRKICIIAGMFCSAAFTLVVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFAS
FICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD
>Mature_453_residues
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIG
ALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWL
VKGGMAPIKSRKICIIAGMFCSAAFTLVVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFAS
FICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=424, Percent_Identity=21.4622641509434, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI6912666, Length=391, Percent_Identity=20.9718670076726, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI9945322, Length=389, Percent_Identity=21.5938303341902, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI148743791, Length=374, Percent_Identity=21.3903743315508, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI154350196, Length=325, Percent_Identity=23.6923076923077, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21322234, Length=393, Percent_Identity=21.3740458015267, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4885441, Length=384, Percent_Identity=20.5729166666667, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI185136021, Length=419, Percent_Identity=24.8210023866348, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI148728191, Length=275, Percent_Identity=22.1818181818182, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367379, Length=453, Percent_Identity=99.3377483443709, Blast_Score=919, Evalue=0.0,
Organism=Escherichia coli, GI1789515, Length=434, Percent_Identity=29.9539170506912, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87082320, Length=433, Percent_Identity=28.8683602771363, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1789152, Length=419, Percent_Identity=29.1169451073986, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI2367193, Length=310, Percent_Identity=28.7096774193548, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082310, Length=453, Percent_Identity=22.2958057395143, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082071, Length=293, Percent_Identity=22.1843003412969, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25141316, Length=473, Percent_Identity=23.8900634249471, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25141318, Length=410, Percent_Identity=23.4146341463415, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25141341, Length=373, Percent_Identity=23.3243967828418, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI86561091, Length=391, Percent_Identity=23.5294117647059, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533556, Length=416, Percent_Identity=22.3557692307692, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115533554, Length=416, Percent_Identity=22.3557692307692, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554148, Length=310, Percent_Identity=25.4838709677419, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71997452, Length=404, Percent_Identity=21.039603960396, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17566884, Length=294, Percent_Identity=25.1700680272109, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17535049, Length=443, Percent_Identity=20.5417607223476, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=393, Percent_Identity=22.9007633587786, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=373, Percent_Identity=22.5201072386059, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554962, Length=315, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24648416, Length=448, Percent_Identity=22.9910714285714, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356189, Length=448, Percent_Identity=22.9910714285714, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641682, Length=402, Percent_Identity=22.8855721393035, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639764, Length=429, Percent_Identity=21.6783216783217, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24654215, Length=373, Percent_Identity=24.3967828418231, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922400, Length=373, Percent_Identity=24.3967828418231, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24655271, Length=446, Percent_Identity=23.3183856502242, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573708, Length=467, Percent_Identity=20.7708779443255, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573707, Length=467, Percent_Identity=20.7708779443255, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20130135, Length=446, Percent_Identity=23.3183856502242, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583789, Length=305, Percent_Identity=22.6229508196721, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573299, Length=414, Percent_Identity=23.6714975845411, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24584153, Length=393, Percent_Identity=21.882951653944, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550460, Length=440, Percent_Identity=23.4090909090909, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24658658, Length=449, Percent_Identity=22.4944320712695, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24654037, Length=387, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654041, Length=387, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24655255, Length=405, Percent_Identity=23.2098765432099, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864456, Length=332, Percent_Identity=23.4939759036145, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654039, Length=332, Percent_Identity=23.4939759036145, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550364, Length=295, Percent_Identity=23.0508474576271, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130167, Length=311, Percent_Identity=20.2572347266881, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129235, Length=410, Percent_Identity=20.9756097560976, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49400; Mature: 49400

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSS
CCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLF
CCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHCCCE
VSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
ECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCC
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAA
CCCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLVVPQATTSMTAVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHEEECCHHHHHHHHH
LIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPIITGFIVDTTHS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
FRLALIICGCVTAAGALAYIFLVRQPINDPRKD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSS
CCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLF
CCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHCCCE
VSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
ECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCC
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAA
CCCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLVVPQATTSMTAVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHEEECCHHHHHHHHH
LIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPIITGFIVDTTHS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
FRLALIICGCVTAAGALAYIFLVRQPINDPRKD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]