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The map label for this gene is leuE [H]

Identifier: 157155360

GI number: 157155360

Start: 2007494

End: 2008132

Strand: Reverse

Name: leuE [H]

Synonym: EcE24377A_2024

Alternate gene names: 157155360

Gene position: 2008132-2007494 (Counterclockwise)

Preceding gene: 157159337

Following gene: 157156692

Centisome position: 40.33

GC content: 45.38

Gene sequence:

>639_bases
GTGTTCGCTGAATACGGGGTTCTGAATTACTGGACCTATCTGGTTGGGGCCATTTTTATTGTGTTGGTGCCAGGGCCAAA
TACCCTGTTTGTACTCAAAAATAGCGTCAGTAGCGGTATGAAAGGCGGTTATCTTGCGGCCTGCGGTGTATTTATTGGCG
ATGCAGTATTGATGTTTCTGGCATGGGCTGGAGTGGCGACATTAATTAAGACCACCCCGATATTATTCAACATTGTACGT
TATCTTGGTGCGTTTTATTTGCTCTATCTGGGGAGTAAAATTCTCTACGCGACCCTGAAGGGTAAAAATAACGAGGCCAA
ATCCGATGAGCCCCAATACGGGGCCATTTTTAAACGCGCGTTAATTTTGAGCCTGACTAATCCGAAAGCCATTTTGTTCT
ATGTGTCGTTTTTCGTACAGTTTATCGATGTTAATGCCCCACATACGGGAATTTCATTCTTTATTCTGGCGACGACGCTG
GAACTGGTGAGTTTCTGCTATTTGAGCTTCCTGATTATTTCTGGTGCTTTTGTCACGCAGTACATACGTACCAAAAAGAA
ACTGGCTAAAGTTGGCAACTCACTGATTGGTTTGATGTTCGTGGGTTTCGCCGCCCGACTGGCGACGCTGCAATCCTGA

Upstream 100 bases:

>100_bases
TCGGGTTAAAACCTGATTTTCTCCTTTCTAAGCCGCTACAGATTGGTTAGCATATTCACCTTTAATCGCGCATGATCGAA
AGATAATTAAAGAGGTTAAT

Downstream 100 bases:

>100_bases
TACATTCAGCCCGCGTTGTCGCGGGCTTCCCACTTGTAATCCTCCCTGATTTTTCTCTGATATGGTGCTAAAAAGTAACC
AATAAATGGTATTTAAAATG

Product: leucine export protein LeuE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGYLAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVR
YLGAFYLLYLGSKILYATLKGKNNEAKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS

Sequences:

>Translated_212_residues
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGYLAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVR
YLGAFYLLYLGSKILYATLKGKNNEAKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS
>Mature_212_residues
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGYLAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVR
YLGAFYLLYLGSKILYATLKGKNNEAKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=212, Percent_Identity=99.0566037735849, Blast_Score=416, Evalue=1e-118,
Organism=Escherichia coli, GI1786522, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI48994979, Length=203, Percent_Identity=27.0935960591133, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI48994978, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23258; Mature: 23258

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGYLAACGVFIGDAVLMFL
CCCCCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGKNNEAKSDEPQYGAIFKRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCHHHHHHHHH
LILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTLELVSFCYLSFLIISGAFVTQ
HHHEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRTKKKLAKVGNSLIGLMFVGFAARLATLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGYLAACGVFIGDAVLMFL
CCCCCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGKNNEAKSDEPQYGAIFKRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCHHHHHHHHH
LILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTLELVSFCYLSFLIISGAFVTQ
HHHEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRTKKKLAKVGNSLIGLMFVGFAARLATLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]