Click here to switch to the map view.

The map label for this gene is anmK

Identifier: 157155348

GI number: 157155348

Start: 1844327

End: 1845436

Strand: Reverse

Name: anmK

Synonym: EcE24377A_1850

Alternate gene names: 157155348

Gene position: 1845436-1844327 (Counterclockwise)

Preceding gene: 157157476

Following gene: 157158848

Centisome position: 37.06

GC content: 54.95

Gene sequence:

>1110_bases
ATGAAATCGGGCCGCTTTATTGGCGTTATGTCAGGCACCAGCCTTGATGGTGTTGATGTTGTGTTGGCGACAATAGATGA
ACACCGGGTCGCACAGCTGGCAAGCTTGAGCTGGCCGATCCCGGTGTCTCTGAAACAGGCTGTACTGGATATTTGCCAGG
GCCAGCAGCTTACACTTTCGCAGTTTGGACAGCTTGATACTCAACTCGGGCGACTTTTTGCTGATGCGGTCAATGCCTTG
CTTAAGGAACAAAACCTGCAGGCGAGAGATATAGTTGCGATCGGCTGTCACGGTCAAGCCGTCTGGCATGAACCGACGGG
CGTGGCACCACACACTTTACAGATTGGCGATAACAATCAAATTGTGGCACGCACCGGAATTACGGTTGTCGGTGATTTTC
GCCGTCGCGATATTGCCTTGGGAGGACAAGGCGCACCGCTGGTACCTGCGTTCCATCATGCCTTGCTGGCTCACTCAACC
GAGCGACGAATGGTGCTCAATATTGGCGGCATCGCCAATCTGTCACTGCTCATTCCTGGGCAGCCGGTTGGCGGCTACGA
TACCGGTCCTGGTAACATGCTGATGGATGCCTGGATCTGGCGTCAGGCCGGTAAACCTTACGATAAAGATGCCGAGTGGG
CACGGGCGGGTAAAGTTATTCTCCCACTGCTGCAAAATATGCTCAGCGACCCATATTTCTCGCAACCTGCACCGAAAAGC
ACCGGACGCGAATACTTTAACTACGGCTGGCTGGAGCGCCATTTACGCCATTTTCCGGGTGTTGATCCCCGTGATGTTCA
GGCCACACTGGCAGAACTCACCGCCGTGACCATTTCTGAACAAGTTTTGTTGAGCGGTGGCTGCGAACGATTGATGGTAT
GTGGTGGAGGTAGTCGTAATCCGCTACTCATGGCGCGTCTGGCGGCATTACTGCCAGGCACAGAAGTCACCACCACCGAT
GCCGTTGGCATTAGTGGCGATGACATGGAAGCATTGGCTTTCGCCTGGCTTGCCTGGCGGACGCTGGCGGGATTACCAGG
AAATCTGCCTTCCGTCACTGGCGCAAGCCAGGAGACGGTACTGGGGGCTATTTTCCCTGCTAACCCGTGA

Upstream 100 bases:

>100_bases
TGTTTTACTACCAACGGTAAAAATCGGTCATTCCGCATGGTATTCACGAAAAGTTTATGTTTGAGTGGTGCGCAAACGTC
AGATTGAAAAAGGATGAACT

Downstream 100 bases:

>100_bases
TATCAGAGTTAACTGAATTTTTCTTACCGCGTCTGCCGTTACACTTGGAACATTAGGGAGGGCGTATTGCCCTCCAGACC
AGGAAAGTCTTCGGGAAATG

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNAL
LKEQNLQARDIVAIGCHGQAVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHST
ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKS
TGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTD
AVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP

Sequences:

>Translated_369_residues
MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNAL
LKEQNLQARDIVAIGCHGQAVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHST
ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKS
TGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTD
AVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
>Mature_369_residues
MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNAL
LKEQNLQARDIVAIGCHGQAVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHST
ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKS
TGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTD
AVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=369, Percent_Identity=99.1869918699187, Blast_Score=743, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_ECO24 (A7ZMA2)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001462931.1
- ProteinModelPortal:   A7ZMA2
- SMR:   A7ZMA2
- STRING:   A7ZMA2
- EnsemblBacteria:   EBESCT00000018805
- GeneID:   5587775
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_1850
- NMPDR:   fig|331111.3.peg.4277
- eggNOG:   COG2377
- GeneTree:   EBGT00050000010687
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- ProtClustDB:   PRK09585
- BioCyc:   ECOL331111:ECE24377A_1850-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 39485; Mature: 39485

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLS
CCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHH
QFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQAVWHEPTGVAPHTLQIGDNNQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCCCCEEEECCCCE
IVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHSTERRMVLNIGGIANLSLLIPG
EEEECCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECC
QPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKS
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
TGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRN
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
PLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETV
HHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
LGAIFPANP
EEEEECCCC
>Mature Secondary Structure
MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLS
CCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHH
QFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQAVWHEPTGVAPHTLQIGDNNQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCCCCEEEECCCCE
IVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHSTERRMVLNIGGIANLSLLIPG
EEEECCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECC
QPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKS
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
TGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRN
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
PLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETV
HHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
LGAIFPANP
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA