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The map label for this gene is cheW

Identifier: 157155275

GI number: 157155275

Start: 2100433

End: 2100936

Strand: Reverse

Name: cheW

Synonym: EcE24377A_2120

Alternate gene names: 157155275

Gene position: 2100936-2100433 (Counterclockwise)

Preceding gene: 157155369

Following gene: 157157023

Centisome position: 42.19

GC content: 50.99

Gene sequence:

>504_bases
ATGACCGGTATGACGAATGTAACAAAGCTGGCCAGCGAGCCGTCAGGCCAGGAATTTCTGGTATTTACCCTTGGTGATGA
AGAGTACGGTATTGATATCCTGAAAGTGCAGGAGATCCGTGGCTACGATCAGGTAACACGGATTGCGAACACGCCAGCGT
TTATCAAAGGCGTCACGAATCTGCGCGGGGTTATTGTGCCGATTGTTGACTTACGAATTAAGTTCAGCCAGGTGGATGTG
GACTATAACGACAACACGGTAGTTATCGTCCTGAATCTCGGACAACGGGTGGTTGGCATCGTGGTTGACGGCGTTTCAGA
CGTGCTTTCATTGACGGCGGAGCAAATTCGTCCGGCACCAGAATTTGCCGTGACGCTTTCAACAGAATATCTCACTGGAC
TGGGCGCACTGGGCGACCGTATGTTGATTCTGGTGAACATCGAAAAACTGCTGAACAGCGAAGAGATGGCGCTGTTAGAT
AGCGCGGCGTCAGAAGTGGCGTAA

Upstream 100 bases:

>100_bases
GCAGCGTGGCACTGATTGTTGATGTCTCCGCCTTGCAGGCGATAAACCGCGAACAACGTATGGCGAACACCGCCGCCTGA
ATGAGTAAAAAGGTAACAAT

Downstream 100 bases:

>100_bases
TTCTCCCGATTTCCTCAATTGAAATGAACCCGATGATCTGCGCATCGGGTTTTTTATTTCAATTTCGCGGCGGGTGGCAT
CAGCAATAAAGTTTCCCCCC

Product: purine-binding chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDV
DYNDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
SAASEVA

Sequences:

>Translated_167_residues
MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDV
DYNDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
SAASEVA
>Mature_166_residues
TGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVD
YNDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLDS
AASEVA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain

Homologues:

Organism=Escherichia coli, GI1788196, Length=167, Percent_Identity=100, Blast_Score=330, Evalue=4e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEW_ECO57 (P0A966)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   E90953
- RefSeq:   NP_288324.1
- RefSeq:   NP_310624.1
- ProteinModelPortal:   P0A966
- SMR:   P0A966
- EnsemblBacteria:   EBESCT00000028604
- EnsemblBacteria:   EBESCT00000057464
- GeneID:   914106
- GeneID:   961859
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2941
- KEGG:   ecs:ECs2597
- GeneTree:   EBGT00050000011238
- HOGENOM:   HBG752473
- OMA:   KPAPEFG
- ProtClustDB:   PRK10612
- BioCyc:   ECOL83334:ECS2597-MONOMER
- GO:   GO:0005737
- GO:   GO:0006935
- InterPro:   IPR002545
- SMART:   SM00260

Pfam domain/function: PF01584 CheW; SSF50341 CheW

EC number: NA

Molecular weight: Translated: 18084; Mature: 17953

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTN
CCCCCCHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCHHHHHHHCCCCHHHHHHCC
LRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAP
CCEEEEEEEEEEEEEEEEEECCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHCCCCC
EFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSAASEVA
CEEEEEEHHHHHHHCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTN
CCCCCHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCHHHHHHHCCCCHHHHHHCC
LRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAP
CCEEEEEEEEEEEEEEEEEECCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHCCCCC
EFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSAASEVA
CEEEEEEHHHHHHHCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796