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The map label for this gene is fecB [H]

Identifier: 157155064

GI number: 157155064

Start: 4857434

End: 4858342

Strand: Reverse

Name: fecB [H]

Synonym: EcE24377A_4867

Alternate gene names: 157155064

Gene position: 4858342-4857434 (Counterclockwise)

Preceding gene: 157155746

Following gene: 157159183

Centisome position: 97.56

GC content: 57.43

Gene sequence:

>909_bases
GTGATTATGTTGGCATTTATCCGTTTTCTTTTTGCAGGCCTGCTGCTGGTGATCAGCCACGCCTTTGCCGCCATGGTTCA
GGACGAACACGGCACGTTTACACTCGAAAAAACGCCACAACGGATTGTGGTGCTGGAACTCTCGTTCGCCGATGCGCTGG
CCGCCGTGGACGTCAGCCCGATCGGTATTGCCGACGATAACGATGCAAAACGCATCCTGCCCGAAGTGCGTGCGCACCTG
AAACCGTGGCAGTCCGTCGGAACGCGCGCGCAGCCGAGCCTGGAAGCCATTGCCGCTCTGAAACCAGACCTGATCATTGC
CGACAGCAGTCGCCATGCGGGGGTTTACATCGCCTTGCAGCAAATCGCGCCGGTACTGCTGCTTAAGTCCCGCAACGAAA
CCTACGCTGAAAATTTGCAATCTGCGGCTATCATCGGCGAAATGGTGGGTAAAAAGCGAGAGATGCAGGCACGTCTGGAA
CAACATAAAGAGAGGATGGCGCAGTGGGCCAGCCAGCTTCCCAAAGGGACACGCGTGGCCTTTGGCACATCACGCGAACA
GCAATTCAACCTGCATACTCAGGAGACCTGGACCGGCAGCGTGCTGGCCTCTCTGGGGCTGAACGTTCCCGCTGCGATGG
CGGGTTCGTCCATGCCGTCCATCGGCCTGGAGCAACTGCTGGCGGTCAATCCTGCCTGGCTGCTGGTTGCCCACTATCGC
GAAGAGAGCATTGTTAAACGCTGGCAACAAGATCCGCTCTGGCAGATGTTAACCGCCGCGCAGAAGCAGCAGGTTGCTTC
GGTCGACAGTAACACCTGGGCGCGGATGCGCGGTATTTTTGCTGCAGAGCGTATTGCCGCTGACACGGTAAAAATCTTCC
ACCATCAGCCGCTTACCGTTGTGAAATGA

Upstream 100 bases:

>100_bases
ACAAAGGCATCTATGCAGGCCAGCCGCGCACGCTGTATATGCAGGGGTCGTTGAAGTTCTGATGTGTTAACGCCCGGCTT
GCCGGGCTTTTAGCTGGAAT

Downstream 100 bases:

>100_bases
CCGCGATAAAACACCCGATGCTGCTGTGGGGGCTTCCCGTTGCAGCACTTATTATTATTTTCTGGCTGAGTCTGTTTTGC
TACTCGGCCATTCCTGTTTC

Product: iron-dicitrate transporter substrate-binding subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron(III) dicitrate-binding periplasmic protein [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MIMLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLELSFADALAAVDVSPIGIADDNDAKRILPEVRAHL
KPWQSVGTRAQPSLEAIAALKPDLIIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLE
QHKERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGSSMPSIGLEQLLAVNPAWLLVAHYR
EESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRGIFAAERIAADTVKIFHHQPLTVVK

Sequences:

>Translated_302_residues
MIMLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLELSFADALAAVDVSPIGIADDNDAKRILPEVRAHL
KPWQSVGTRAQPSLEAIAALKPDLIIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLE
QHKERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGSSMPSIGLEQLLAVNPAWLLVAHYR
EESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRGIFAAERIAADTVKIFHHQPLTVVK
>Mature_302_residues
MIMLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLELSFADALAAVDVSPIGIADDNDAKRILPEVRAHL
KPWQSVGTRAQPSLEAIAALKPDLIIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLE
QHKERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGSSMPSIGLEQLLAVNPAWLLVAHYR
EESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRGIFAAERIAADTVKIFHHQPLTVVK

Specific function: Binds citrate-dependent Fe(3+); part of the binding- protein-dependent transport system for uptake of citrate-dependent Fe(3+) [H]

COG id: COG4594

COG function: function code P; ABC-type Fe3+-citrate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082411, Length=300, Percent_Identity=99, Blast_Score=603, Evalue=1e-174,
Organism=Escherichia coli, GI1786807, Length=272, Percent_Identity=25.3676470588235, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 33411; Mature: 33411

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLELSFADALAAVDVSP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEHHHHHHHCCCCC
IGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDLIIADSSRHAGVYIALQ
CCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHCCCCEEEECCCCCCCCEEEHH
QIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQHKERMAQWASQLPKGTRVA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGSSMPSIGLEQLLAVNPAWLLVAHYR
ECCCCCHHCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHCCCHHEEEEHHH
EESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRGIFAAERIAADTVKIFHHQPLTV
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VK
CC
>Mature Secondary Structure
MIMLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLELSFADALAAVDVSP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEHHHHHHHCCCCC
IGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDLIIADSSRHAGVYIALQ
CCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHCCCCEEEECCCCCCCCEEEHH
QIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQHKERMAQWASQLPKGTRVA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGSSMPSIGLEQLLAVNPAWLLVAHYR
ECCCCCHHCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHCCCHHEEEEHHH
EESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRGIFAAERIAADTVKIFHHQPLTV
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2651410; 7610040; 9278503 [H]