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The map label for this gene is proP [H]

Identifier: 156978058

GI number: 156978058

Start: 1970740

End: 1971942

Strand: Direct

Name: proP [H]

Synonym: VIBHAR_06862

Alternate gene names: 156978058

Gene position: 1970740-1971942 (Clockwise)

Preceding gene: 156978057

Following gene: 156978061

Centisome position: 89.42

GC content: 41.15

Gene sequence:

>1203_bases
ATGCTATTGACTTGGAAGCAAAGGTTGGCTGTCGTTGCTGGCAATGCAATGGAGTTTTATGATATTGCTGTATTCGCAGC
AATCGCCCCCTTTCTCACTCAAATTATGGAAAACCATGGATATGAGAATGCTACGACTCTAATATGGGGGATGTTTGCTT
TACGCTTTATACTACGCCCTCTTGGTGGCTATATCGTTGGAAACATCGCAGACTACTACGGCAAAAAAAATGCATTAATA
ATGACTAGTAGCCTTACTGGTTTCGCAACGCTCACTATGGCCGTACTGCCCACCCAACTTGAGTACGTTGTTTTTTACTT
TCTCTTTCTGCAAATTATCCAAGCATTTAGTTTTGGAGGAGAGTATCCAACCGTTATAAATTATTTAACGAACCACTCCC
CAAAAAAAGAAGTAGCAAGAACAAGCTGCCTCATTGTAGCGAGCTCTATTGTCGGTGTTTTATTGTCTATCGCTATTGTT
GAAACACTAAAGTTCACGCTTTCAAGTGAAGCAATGCAAAGTTATGGATGGAGAATCCCACTTCTCATTGGTGGAGTTAA
TATTGCTGTCAGTTTTTGGTTTCGCTCTAAATTACCTAAAGAAGTCAACACTGTTGTAGAAAAAACAAAGCAGAGTCCAA
GACAGTGGATACCACTATTCTTTATTTCGATGGGGGGGGCGGTTGTCTTTTATATACAAAATCTATCGAGCACTATTTTG
CAAAAATCAGTCGATATTCCCCACTTCTCGCTGATAAACTCGTCATTATTGTTGGCATGTATTCTATTATCTGGTTACTT
AACCGATAAGATAACCACGCCAAAACACGCTTTTAGAACAAGTTCTTTGGCTGGCGCACTTCTTTATTTTCCCACTTACT
GGCTATTAACTCACGCAATAACAGAAGTAGCCATCGTAGGAATGCTCATCATAAGCATAATTTCTGCAATAATACTCGCC
AATTTAGCCGTGGTCCTCGCGCAAATAGCGAAAAACCAAACGGTAGTTCTTGGACTTTGTTACAATATCGCATTGTCTAT
TTTTGGTGGTTTAACTCCGCTAGTTGTGGCAATGACAACTGAATATGATGCTAGCTTTGTCGGATTGTACGCAGCTCTAT
GTGTGATACCAGCCCTTCTGTCCGTGCATTATTCTCTCACGCCACCCGCTCAGCCCCATACCCCTACTCTTCAACAAGAC
TGA

Upstream 100 bases:

>100_bases
GTAGTGAAATACAGAAAGCGAGATTAGGTCTCTTTTCGTACTTTTTCGCTCTAGACCCAGAATGTAATCAAGTAGAATTT
ATACAGAGGAATAATATCTA

Downstream 100 bases:

>100_bases
ATGATTCTAATGGGTTAAAAGGCTAACTTCAGAGACAATATCGTTTTTTCTAAATGAAAGACGATATTGTCTATAAAAAA
CTCAAAAGCAATAAGAGAAT

Product: hypothetical protein

Products: Proton [Cytoplasm]; 2-oxoglutarate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MLLTWKQRLAVVAGNAMEFYDIAVFAAIAPFLTQIMENHGYENATTLIWGMFALRFILRPLGGYIVGNIADYYGKKNALI
MTSSLTGFATLTMAVLPTQLEYVVFYFLFLQIIQAFSFGGEYPTVINYLTNHSPKKEVARTSCLIVASSIVGVLLSIAIV
ETLKFTLSSEAMQSYGWRIPLLIGGVNIAVSFWFRSKLPKEVNTVVEKTKQSPRQWIPLFFISMGGAVVFYIQNLSSTIL
QKSVDIPHFSLINSSLLLACILLSGYLTDKITTPKHAFRTSSLAGALLYFPTYWLLTHAITEVAIVGMLIISIISAIILA
NLAVVLAQIAKNQTVVLGLCYNIALSIFGGLTPLVVAMTTEYDASFVGLYAALCVIPALLSVHYSLTPPAQPHTPTLQQD

Sequences:

>Translated_400_residues
MLLTWKQRLAVVAGNAMEFYDIAVFAAIAPFLTQIMENHGYENATTLIWGMFALRFILRPLGGYIVGNIADYYGKKNALI
MTSSLTGFATLTMAVLPTQLEYVVFYFLFLQIIQAFSFGGEYPTVINYLTNHSPKKEVARTSCLIVASSIVGVLLSIAIV
ETLKFTLSSEAMQSYGWRIPLLIGGVNIAVSFWFRSKLPKEVNTVVEKTKQSPRQWIPLFFISMGGAVVFYIQNLSSTIL
QKSVDIPHFSLINSSLLLACILLSGYLTDKITTPKHAFRTSSLAGALLYFPTYWLLTHAITEVAIVGMLIISIISAIILA
NLAVVLAQIAKNQTVVLGLCYNIALSIFGGLTPLVVAMTTEYDASFVGLYAALCVIPALLSVHYSLTPPAQPHTPTLQQD
>Mature_400_residues
MLLTWKQRLAVVAGNAMEFYDIAVFAAIAPFLTQIMENHGYENATTLIWGMFALRFILRPLGGYIVGNIADYYGKKNALI
MTSSLTGFATLTMAVLPTQLEYVVFYFLFLQIIQAFSFGGEYPTVINYLTNHSPKKEVARTSCLIVASSIVGVLLSIAIV
ETLKFTLSSEAMQSYGWRIPLLIGGVNIAVSFWFRSKLPKEVNTVVEKTKQSPRQWIPLFFISMGGAVVFYIQNLSSTIL
QKSVDIPHFSLINSSLLLACILLSGYLTDKITTPKHAFRTSSLAGALLYFPTYWLLTHAITEVAIVGMLIISIISAIILA
NLAVVLAQIAKNQTVVLGLCYNIALSIFGGLTPLVVAMTTEYDASFVGLYAALCVIPALLSVHYSLTPPAQPHTPTLQQD

Specific function: May be a proton symporter invoved in the uptake of osmolytes such as proline and glycine betaine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788942, Length=365, Percent_Identity=25.7534246575342, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788292, Length=397, Percent_Identity=24.1813602015113, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1790550, Length=220, Percent_Identity=25.4545454545455, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43889; Mature: 43889

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTWKQRLAVVAGNAMEFYDIAVFAAIAPFLTQIMENHGYENATTLIWGMFALRFILRP
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LGGYIVGNIADYYGKKNALIMTSSLTGFATLTMAVLPTQLEYVVFYFLFLQIIQAFSFGG
HCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EYPTVINYLTNHSPKKEVARTSCLIVASSIVGVLLSIAIVETLKFTLSSEAMQSYGWRIP
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LLIGGVNIAVSFWFRSKLPKEVNTVVEKTKQSPRQWIPLFFISMGGAVVFYIQNLSSTIL
EEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEHHHHHHHHHH
QKSVDIPHFSLINSSLLLACILLSGYLTDKITTPKHAFRTSSLAGALLYFPTYWLLTHAI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TEVAIVGMLIISIISAIILANLAVVLAQIAKNQTVVLGLCYNIALSIFGGLTPLVVAMTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHHHHEEEC
EYDASFVGLYAALCVIPALLSVHYSLTPPAQPHTPTLQQD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLTWKQRLAVVAGNAMEFYDIAVFAAIAPFLTQIMENHGYENATTLIWGMFALRFILRP
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LGGYIVGNIADYYGKKNALIMTSSLTGFATLTMAVLPTQLEYVVFYFLFLQIIQAFSFGG
HCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EYPTVINYLTNHSPKKEVARTSCLIVASSIVGVLLSIAIVETLKFTLSSEAMQSYGWRIP
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LLIGGVNIAVSFWFRSKLPKEVNTVVEKTKQSPRQWIPLFFISMGGAVVFYIQNLSSTIL
EEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEHHHHHHHHHH
QKSVDIPHFSLINSSLLLACILLSGYLTDKITTPKHAFRTSSLAGALLYFPTYWLLTHAI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TEVAIVGMLIISIISAIILANLAVVLAQIAKNQTVVLGLCYNIALSIFGGLTPLVVAMTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHHHHEEEC
EYDASFVGLYAALCVIPALLSVHYSLTPPAQPHTPTLQQD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 2-oxoglutarate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 2-oxoglutarate [Periplasm] = Proton [Cytoplasm] + 2-oxoglutarate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10708580 [H]