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The map label for this gene is ptrB [H]

Identifier: 156977944

GI number: 156977944

Start: 1873199

End: 1875289

Strand: Direct

Name: ptrB [H]

Synonym: VIBHAR_06740

Alternate gene names: 156977944

Gene position: 1873199-1875289 (Clockwise)

Preceding gene: 156977943

Following gene: 156977955

Centisome position: 84.99

GC content: 45.77

Gene sequence:

>2091_bases
ATGAACCATTACTCCCAATCGCAACTCGTTGCTCAACAAACCCAAGCACCCGTTGCTAAAAAAGTCCGTCATGCAATGAA
TATTCATGGTGATACACGAATCGATAATTACTACTGGATGCGTGATGATGAGCGCCAAGACCCAGAAATCTTGCAACACC
TTGAGCAAGAGAATCAATACGCAGAAACCGTTTTAAAACACACCGAAGCACTGCAAGAACAGCTGTTTGAAGAGATCAAA
GGTCGTATTGCGAAAGATGACAATTCGGTTCCAGTTCGTAAAGGCAGTTACTACTACTCAAATGAAGTGACGGGCGATAA
CGAATACGAAGTACACCTGCGTGCAAAAGACTTTGCCGGTACAGACAAGCAAGTCATTCTAGATGTTAACGAGCTGGCAA
AAGAGCATGAGTTCTTTAGCATTGGCGGCCTATACGTGAGCCCAAATGAAAACATGCTGGCTTACGGTGAAGATACGCTG
AGCCGCCGTATTTACACCATCAAGATCAAAGACCTCACAACGGGCGAATATCTAAAAGATGAAATTGAAGGCGCCTCAAG
CGCAATCGCATGGCAAAACGATAACCAAGCCTTCTACTACATCAAGAAAGACCCGCAAACACTGTTGGGTTATCAAGTTT
ACCGCCATGTCTTGGGCACACCTCAAACAAGCGATGAGCTAATCTACGAAGAAACCGATAGCGCTTACTACACCTTCTTG
AGTAAGAGTAAAGACGGTGAGCAAGTTTACATTTGGCACTCAAGCACAGAGACAAGTGGCGTATCTGTGATTGATGCTAA
CAACCCGAACGCCAAAGCCGAAGCTTTCTACCCTAGAGAAACTGGCATTGAGTACAGCATCGCCAAACTGGGAGATTGGT
ACTACGTCTACACTAACTACCAAGCTGTCAACTTTCGTTTGATGAAAGTGAAAGCAGAAGAGATGCATGACCGCTCTAAA
TGGGTCGATGTCATTCCTGCCGACGACAACACCCAGCTGGTCGATTTCGACTTGTTCGACGACCACCTTGTTTACGAGCA
ACGCACAAACGGCTTATCCACCGTCAAGGTTCGCCAACTATCGACGGGCAAAGAATTCCCACTTGAATTTAATGACACCG
CGTTTGCGGCTTACCTGACAGGCAACTACGAATTAGATAACTCAAAAGTTCGTATCTACTACAGCAGCCTGACTACACCG
GGTACTTACTACGATTTCGACCTGAATACAGGTGAATCAGAAATCATGAAACAAACACCAGTACTGGGTGATTTTGATGC
TGATAACTACCAGTCAGAGCGAATTATGGTGACCGCTCGTGATGGTAAGCAAGTACCAGTCTCATTGGTTTACCGCAAAG
ACCTATTTAAGAAAGACGGCACCAATCCAATCTACCAATACGGCTACGGCTCTTACGGTTCAACTATTGAACCAACGTTC
CGTTCAACCCGCCTGAGCCTACTTGATCGCGGCTTCGTGTACGCCATCGCTCATATTCGCGGTTCAGAAATGCTAGGGCG
TCCTTGGTATGAAGATGGCAAAAAGCTGACCAAACAAAACACCTTCAATGATTTTATCGATGTAACCAAAGGACTGGTTG
AAGAAGGCTACGGGGCCAAAGATAAAGTCTTTGCTGTTGGAGGCTCAGCAGGTGGCCTGCTAATGGGTGCAATCATCAAC
CAAGCACCAGAGCTTTACCGTGGTATTGGTGCGCATGTTCCTTTTGTCGACGTTGTAACAACCATGCTGGATGAGTCGAT
TCCTCTTACCACCAACGAGTACGATGAATGGGGTAACCCAAATGACAAAACCTACTACGACTACATGCTGAGCTACTCAC
CGTACGATAATGTGAAAACTCAAAACTACCCGAACATGTTGGTGACAACGGGTTTGCATGATTCACAGGTGCAATACTTT
GAGCCAATGAAGTGGGTAGCCAAACTTCGTGAAATGAAGACTGATGATAATGTCTTGCTGTTCAAAACCGATATGGAAGC
AGGCCATGGCGGCGCTTCTGGTCGATTCAAACGATTAAAAGAAGACGCACTTGAGTACGCTTTCTTCCTAGATCTGTTGG
AGACCAAATAA

Upstream 100 bases:

>100_bases
AGGAGTACACAATAAGGATACACAGATGCGTTTCACTTTAACCACGTTGGCCGTATCGGTCGCGCTAGTCGCCGGATGCA
GCAATCAAGGATTACCAACC

Downstream 100 bases:

>100_bases
GCTTTAGTCGTCAATCACTATGAGTCACCGAAACAATGCCCGCTTTTACGCGGGCATTTTTCAATCTAGATACTCGGTGA
CATGACTCAGATGAGCCAAC

Product: protease

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MNHYSQSQLVAQQTQAPVAKKVRHAMNIHGDTRIDNYYWMRDDERQDPEILQHLEQENQYAETVLKHTEALQEQLFEEIK
GRIAKDDNSVPVRKGSYYYSNEVTGDNEYEVHLRAKDFAGTDKQVILDVNELAKEHEFFSIGGLYVSPNENMLAYGEDTL
SRRIYTIKIKDLTTGEYLKDEIEGASSAIAWQNDNQAFYYIKKDPQTLLGYQVYRHVLGTPQTSDELIYEETDSAYYTFL
SKSKDGEQVYIWHSSTETSGVSVIDANNPNAKAEAFYPRETGIEYSIAKLGDWYYVYTNYQAVNFRLMKVKAEEMHDRSK
WVDVIPADDNTQLVDFDLFDDHLVYEQRTNGLSTVKVRQLSTGKEFPLEFNDTAFAAYLTGNYELDNSKVRIYYSSLTTP
GTYYDFDLNTGESEIMKQTPVLGDFDADNYQSERIMVTARDGKQVPVSLVYRKDLFKKDGTNPIYQYGYGSYGSTIEPTF
RSTRLSLLDRGFVYAIAHIRGSEMLGRPWYEDGKKLTKQNTFNDFIDVTKGLVEEGYGAKDKVFAVGGSAGGLLMGAIIN
QAPELYRGIGAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNDKTYYDYMLSYSPYDNVKTQNYPNMLVTTGLHDSQVQYF
EPMKWVAKLREMKTDDNVLLFKTDMEAGHGGASGRFKRLKEDALEYAFFLDLLETK

Sequences:

>Translated_696_residues
MNHYSQSQLVAQQTQAPVAKKVRHAMNIHGDTRIDNYYWMRDDERQDPEILQHLEQENQYAETVLKHTEALQEQLFEEIK
GRIAKDDNSVPVRKGSYYYSNEVTGDNEYEVHLRAKDFAGTDKQVILDVNELAKEHEFFSIGGLYVSPNENMLAYGEDTL
SRRIYTIKIKDLTTGEYLKDEIEGASSAIAWQNDNQAFYYIKKDPQTLLGYQVYRHVLGTPQTSDELIYEETDSAYYTFL
SKSKDGEQVYIWHSSTETSGVSVIDANNPNAKAEAFYPRETGIEYSIAKLGDWYYVYTNYQAVNFRLMKVKAEEMHDRSK
WVDVIPADDNTQLVDFDLFDDHLVYEQRTNGLSTVKVRQLSTGKEFPLEFNDTAFAAYLTGNYELDNSKVRIYYSSLTTP
GTYYDFDLNTGESEIMKQTPVLGDFDADNYQSERIMVTARDGKQVPVSLVYRKDLFKKDGTNPIYQYGYGSYGSTIEPTF
RSTRLSLLDRGFVYAIAHIRGSEMLGRPWYEDGKKLTKQNTFNDFIDVTKGLVEEGYGAKDKVFAVGGSAGGLLMGAIIN
QAPELYRGIGAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNDKTYYDYMLSYSPYDNVKTQNYPNMLVTTGLHDSQVQYF
EPMKWVAKLREMKTDDNVLLFKTDMEAGHGGASGRFKRLKEDALEYAFFLDLLETK
>Mature_696_residues
MNHYSQSQLVAQQTQAPVAKKVRHAMNIHGDTRIDNYYWMRDDERQDPEILQHLEQENQYAETVLKHTEALQEQLFEEIK
GRIAKDDNSVPVRKGSYYYSNEVTGDNEYEVHLRAKDFAGTDKQVILDVNELAKEHEFFSIGGLYVSPNENMLAYGEDTL
SRRIYTIKIKDLTTGEYLKDEIEGASSAIAWQNDNQAFYYIKKDPQTLLGYQVYRHVLGTPQTSDELIYEETDSAYYTFL
SKSKDGEQVYIWHSSTETSGVSVIDANNPNAKAEAFYPRETGIEYSIAKLGDWYYVYTNYQAVNFRLMKVKAEEMHDRSK
WVDVIPADDNTQLVDFDLFDDHLVYEQRTNGLSTVKVRQLSTGKEFPLEFNDTAFAAYLTGNYELDNSKVRIYYSSLTTP
GTYYDFDLNTGESEIMKQTPVLGDFDADNYQSERIMVTARDGKQVPVSLVYRKDLFKKDGTNPIYQYGYGSYGSTIEPTF
RSTRLSLLDRGFVYAIAHIRGSEMLGRPWYEDGKKLTKQNTFNDFIDVTKGLVEEGYGAKDKVFAVGGSAGGLLMGAIIN
QAPELYRGIGAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNDKTYYDYMLSYSPYDNVKTQNYPNMLVTTGLHDSQVQYF
EPMKWVAKLREMKTDDNVLLFKTDMEAGHGGASGRFKRLKEDALEYAFFLDLLETK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=724, Percent_Identity=27.0718232044199, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI284172420, Length=637, Percent_Identity=27.6295133437991, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI284172413, Length=637, Percent_Identity=27.6295133437991, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI70778815, Length=637, Percent_Identity=27.6295133437991, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI284172438, Length=591, Percent_Identity=28.2571912013536, Blast_Score=196, Evalue=9e-50,
Organism=Homo sapiens, GI284172431, Length=591, Percent_Identity=28.2571912013536, Blast_Score=196, Evalue=9e-50,
Organism=Homo sapiens, GI108860686, Length=297, Percent_Identity=31.986531986532, Blast_Score=143, Evalue=7e-34,
Organism=Homo sapiens, GI108860692, Length=218, Percent_Identity=36.2385321100917, Blast_Score=137, Evalue=4e-32,
Organism=Escherichia coli, GI1788150, Length=680, Percent_Identity=48.5294117647059, Blast_Score=669, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=720, Percent_Identity=26.25, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI221510989, Length=716, Percent_Identity=26.536312849162, Blast_Score=191, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 79818; Mature: 79818

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHYSQSQLVAQQTQAPVAKKVRHAMNIHGDTRIDNYYWMRDDERQDPEILQHLEQENQY
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEECCEEEECCCCCCCHHHHHHHHHHHHH
AETVLKHTEALQEQLFEEIKGRIAKDDNSVPVRKGSYYYSNEVTGDNEYEVHLRAKDFAG
HHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEECCCEEECCCCCCCCCEEEEEEECCCCC
TDKQVILDVNELAKEHEFFSIGGLYVSPNENMLAYGEDTLSRRIYTIKIKDLTTGEYLKD
CCCEEEEEHHHHHHHCCEEEECCEEECCCCCEEEECCHHHHCEEEEEEEEECCCCHHHHH
EIEGASSAIAWQNDNQAFYYIKKDPQTLLGYQVYRHVLGTPQTSDELIYEETDSAYYTFL
HHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEE
SKSKDGEQVYIWHSSTETSGVSVIDANNPNAKAEAFYPRETGIEYSIAKLGDWYYVYTNY
ECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCEEECCCCCCCEEEEEECCCEEEEEEEE
QAVNFRLMKVKAEEMHDRSKWVDVIPADDNTQLVDFDLFDDHLVYEQRTNGLSTVKVRQL
EEEEEEEEEEEHHHHCCCCCEEEEEECCCCCEEEEEECCCCCEEEHHHCCCCCEEEEEEE
STGKEFPLEFNDTAFAAYLTGNYELDNSKVRIYYSSLTTPGTYYDFDLNTGESEIMKQTP
CCCCCCCEEECCCEEEEEEECCEEECCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHCC
VLGDFDADNYQSERIMVTARDGKQVPVSLVYRKDLFKKDGTNPIYQYGYGSYGSTIEPTF
CCCCCCCCCCCCCEEEEEECCCCCCCEEEEEHHHHHHCCCCCCEEECCCCCCCCCCCCCH
RSTRLSLLDRGFVYAIAHIRGSEMLGRPWYEDGKKLTKQNTFNDFIDVTKGLVEEGYGAK
HHHHHHHHHCCEEEEEEEECCCHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
DKVFAVGGSAGGLLMGAIINQAPELYRGIGAHVPFVDVVTTMLDESIPLTTNEYDEWGNP
CEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
NDKTYYDYMLSYSPYDNVKTQNYPNMLVTTGLHDSQVQYFEPMKWVAKLREMKTDDNVLL
CCCEEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
FKTDMEAGHGGASGRFKRLKEDALEYAFFLDLLETK
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHYSQSQLVAQQTQAPVAKKVRHAMNIHGDTRIDNYYWMRDDERQDPEILQHLEQENQY
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEECCEEEECCCCCCCHHHHHHHHHHHHH
AETVLKHTEALQEQLFEEIKGRIAKDDNSVPVRKGSYYYSNEVTGDNEYEVHLRAKDFAG
HHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEECCCEEECCCCCCCCCEEEEEEECCCCC
TDKQVILDVNELAKEHEFFSIGGLYVSPNENMLAYGEDTLSRRIYTIKIKDLTTGEYLKD
CCCEEEEEHHHHHHHCCEEEECCEEECCCCCEEEECCHHHHCEEEEEEEEECCCCHHHHH
EIEGASSAIAWQNDNQAFYYIKKDPQTLLGYQVYRHVLGTPQTSDELIYEETDSAYYTFL
HHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEE
SKSKDGEQVYIWHSSTETSGVSVIDANNPNAKAEAFYPRETGIEYSIAKLGDWYYVYTNY
ECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCEEECCCCCCCEEEEEECCCEEEEEEEE
QAVNFRLMKVKAEEMHDRSKWVDVIPADDNTQLVDFDLFDDHLVYEQRTNGLSTVKVRQL
EEEEEEEEEEEHHHHCCCCCEEEEEECCCCCEEEEEECCCCCEEEHHHCCCCCEEEEEEE
STGKEFPLEFNDTAFAAYLTGNYELDNSKVRIYYSSLTTPGTYYDFDLNTGESEIMKQTP
CCCCCCCEEECCCEEEEEEECCEEECCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHCC
VLGDFDADNYQSERIMVTARDGKQVPVSLVYRKDLFKKDGTNPIYQYGYGSYGSTIEPTF
CCCCCCCCCCCCCEEEEEECCCCCCCEEEEEHHHHHHCCCCCCEEECCCCCCCCCCCCCH
RSTRLSLLDRGFVYAIAHIRGSEMLGRPWYEDGKKLTKQNTFNDFIDVTKGLVEEGYGAK
HHHHHHHHHCCEEEEEEEECCCHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
DKVFAVGGSAGGLLMGAIINQAPELYRGIGAHVPFVDVVTTMLDESIPLTTNEYDEWGNP
CEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
NDKTYYDYMLSYSPYDNVKTQNYPNMLVTTGLHDSQVQYFEPMKWVAKLREMKTDDNVLL
CCCEEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
FKTDMEAGHGGASGRFKRLKEDALEYAFFLDLLETK
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]