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The map label for this gene is dctD [H]

Identifier: 156977927

GI number: 156977927

Start: 1854433

End: 1855782

Strand: Reverse

Name: dctD [H]

Synonym: VIBHAR_06722

Alternate gene names: 156977927

Gene position: 1855782-1854433 (Counterclockwise)

Preceding gene: 156977930

Following gene: 156977925

Centisome position: 84.2

GC content: 46.37

Gene sequence:

>1350_bases
ATGGCTTTTAACGACTCCCCTAAAATTGCACTTATCGAAGACGACGATATTGTTCGTCAGGCAACTAGCCAATGGTTACA
GCTGGCGGGATTTGATGTATCGGCATTCAGTCTGGGGGAAGAGGGCAAAGCCGCCATTCTTAGCCAAGAATTTGATGCCA
TTGTGAGTGATGTTCGCCTACCAGACATCGACGGTTTATCGATACTGGAAAGCCTGATTGCCAACCATATTCAAACCCCG
ATTATTTTGATCACTGGCCACGGTGATGTCGATATGGCTGTTGGTGCTTTACAACGCGGTGCGTTTGATTTTATTGAGAA
GCCTTTCCAGCCAGAGCGTCTATCTCAACGCGTGACTGAGGCCGTTGAGAGTTATCGCGCACAAACTTCTACTCAAGATC
GTCAGGAGTATCTTTCTAGCATTAGCGGCTTAGAAGAAGTGTTGGTTGGGCGAAGCAAAGTGATGCAAAAACTAAGGGAG
CAAGTTGCCAAGCTAGCGCGAATTGATACTAACGTGATCATTTATGGTGAAACAGGTTGTGGTAAAGAGCTGGTGGCCAC
CAGTTTGCATAATGAGAGCCAACGGAGAGCCCATCACTTTGTGCCTATCAACTGTGGCGCAATTCCTGAAACACTGTTCG
AGAGCGAATTATTTGGCCATGAAGCTGGCGCATTTACCGGCGCGGCCAAAAAGCGCATTGGTAAGCTTGAATACGCAGAT
AAGGGCACCTTGTTTTTTGATGAAGTAGAAAGCATGCCTATGTCAATGCAAGTGAAAGTATTGCGCGCTCTTCAAGAACA
CACCATAGAGAGAGTAGGTGGCAACCAACAAATCTCTGTTGATTTACGGGTGATCGCGGCGGCGAAAGAAGATCTCAATG
ATCATGACGACTTTCGTCAGGATTTATATTATCGCCTTAATGTGGCGCAGATCTATCTACCGCCACTGAGAGAGCGTGAA
GAAGACGCATTGATCTTATTCGAACATTTCACATTGAAGAACAACCCAAACTGCCGACCTGTGAGTGAAGCTGATAGAAA
AGCCATTCTTGCTTATGCGTGGCCGGGCAATGTGCGGGAACTAAGAAACGTGGCCATAAGGTTCGCGTTAGACAACACCA
TTTCGGTTATGGAAATTCTCTCTAGTCGCCCTTCCTCGACAAACGAAGAAACACAAGCAGGTGTGCCGTTGGTTATTCAG
CTGCATAATTTTGAACGCAAGGTGCTACATGATTCGTTAGTTCGAAACCAAGGAAGAATTACGGATGTGATGGTCGAATT
AGATTTACCACGCCGAACCCTCAACCAAAAGATGCAGAAGTTTGGGTTGAATCGCTCTGATTACACGTAG

Upstream 100 bases:

>100_bases
TAAGCAAGAAGTGAGATCTAGCTCCTTTTCTCCACAGTGGTTTTTGCTACCGTTAGCACACCACGATGAATTCCTATACT
TATAAATCAGGCAGTAACGT

Downstream 100 bases:

>100_bases
AAAAAACGGCTTCACTTAGGAAGCCGTTTTTTGTTGAGGTACTTATTTGTTAAGGTACTTGCCAATCTAGGCTTGGTTCA
CGAATTCGGTGCGTTGTTGG

Product: acetoacetate metabolism regulatory protein AtoC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MAFNDSPKIALIEDDDIVRQATSQWLQLAGFDVSAFSLGEEGKAAILSQEFDAIVSDVRLPDIDGLSILESLIANHIQTP
IILITGHGDVDMAVGALQRGAFDFIEKPFQPERLSQRVTEAVESYRAQTSTQDRQEYLSSISGLEEVLVGRSKVMQKLRE
QVAKLARIDTNVIIYGETGCGKELVATSLHNESQRRAHHFVPINCGAIPETLFESELFGHEAGAFTGAAKKRIGKLEYAD
KGTLFFDEVESMPMSMQVKVLRALQEHTIERVGGNQQISVDLRVIAAAKEDLNDHDDFRQDLYYRLNVAQIYLPPLRERE
EDALILFEHFTLKNNPNCRPVSEADRKAILAYAWPGNVRELRNVAIRFALDNTISVMEILSSRPSSTNEETQAGVPLVIQ
LHNFERKVLHDSLVRNQGRITDVMVELDLPRRTLNQKMQKFGLNRSDYT

Sequences:

>Translated_449_residues
MAFNDSPKIALIEDDDIVRQATSQWLQLAGFDVSAFSLGEEGKAAILSQEFDAIVSDVRLPDIDGLSILESLIANHIQTP
IILITGHGDVDMAVGALQRGAFDFIEKPFQPERLSQRVTEAVESYRAQTSTQDRQEYLSSISGLEEVLVGRSKVMQKLRE
QVAKLARIDTNVIIYGETGCGKELVATSLHNESQRRAHHFVPINCGAIPETLFESELFGHEAGAFTGAAKKRIGKLEYAD
KGTLFFDEVESMPMSMQVKVLRALQEHTIERVGGNQQISVDLRVIAAAKEDLNDHDDFRQDLYYRLNVAQIYLPPLRERE
EDALILFEHFTLKNNPNCRPVSEADRKAILAYAWPGNVRELRNVAIRFALDNTISVMEILSSRPSSTNEETQAGVPLVIQ
LHNFERKVLHDSLVRNQGRITDVMVELDLPRRTLNQKMQKFGLNRSDYT
>Mature_448_residues
AFNDSPKIALIEDDDIVRQATSQWLQLAGFDVSAFSLGEEGKAAILSQEFDAIVSDVRLPDIDGLSILESLIANHIQTPI
ILITGHGDVDMAVGALQRGAFDFIEKPFQPERLSQRVTEAVESYRAQTSTQDRQEYLSSISGLEEVLVGRSKVMQKLREQ
VAKLARIDTNVIIYGETGCGKELVATSLHNESQRRAHHFVPINCGAIPETLFESELFGHEAGAFTGAAKKRIGKLEYADK
GTLFFDEVESMPMSMQVKVLRALQEHTIERVGGNQQISVDLRVIAAAKEDLNDHDDFRQDLYYRLNVAQIYLPPLREREE
DALILFEHFTLKNNPNCRPVSEADRKAILAYAWPGNVRELRNVAIRFALDNTISVMEILSSRPSSTNEETQAGVPLVIQL
HNFERKVLHDSLVRNQGRITDVMVELDLPRRTLNQKMQKFGLNRSDYT

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=456, Percent_Identity=36.1842105263158, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI1790299, Length=364, Percent_Identity=39.010989010989, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1790437, Length=444, Percent_Identity=36.7117117117117, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI1788905, Length=361, Percent_Identity=37.9501385041551, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1789087, Length=400, Percent_Identity=37, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87082117, Length=373, Percent_Identity=37.5335120643432, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=44.5887445887446, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1786524, Length=243, Percent_Identity=43.6213991769547, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789233, Length=323, Percent_Identity=38.0804953560372, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=36.9085173501577, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI1787583, Length=227, Percent_Identity=40.0881057268723, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1789828, Length=253, Percent_Identity=33.201581027668, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87081858, Length=295, Percent_Identity=27.7966101694915, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=124, Percent_Identity=36.2903225806452, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789402, Length=128, Percent_Identity=30.46875, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789809, Length=112, Percent_Identity=36.6071428571429, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50489; Mature: 50358

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNDSPKIALIEDDDIVRQATSQWLQLAGFDVSAFSLGEEGKAAILSQEFDAIVSDVRL
CCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCCC
PDIDGLSILESLIANHIQTPIILITGHGDVDMAVGALQRGAFDFIEKPFQPERLSQRVTE
CCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHH
AVESYRAQTSTQDRQEYLSSISGLEEVLVGRSKVMQKLREQVAKLARIDTNVIIYGETGC
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GKELVATSLHNESQRRAHHFVPINCGAIPETLFESELFGHEAGAFTGAAKKRIGKLEYAD
CHHHHHHHHCCHHHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
KGTLFFDEVESMPMSMQVKVLRALQEHTIERVGGNQQISVDLRVIAAAKEDLNDHDDFRQ
CCCEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEHHHCCCCHHHHHH
DLYYRLNVAQIYLPPLREREEDALILFEHFTLKNNPNCRPVSEADRKAILAYAWPGNVRE
HHHHEEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCHHH
LRNVAIRFALDNTISVMEILSSRPSSTNEETQAGVPLVIQLHNFERKVLHDSLVRNQGRI
HHHHHHEEEECCHHHHHHHHHCCCCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHCCCCE
TDVMVELDLPRRTLNQKMQKFGLNRSDYT
EEEEEEECCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AFNDSPKIALIEDDDIVRQATSQWLQLAGFDVSAFSLGEEGKAAILSQEFDAIVSDVRL
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCCC
PDIDGLSILESLIANHIQTPIILITGHGDVDMAVGALQRGAFDFIEKPFQPERLSQRVTE
CCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHH
AVESYRAQTSTQDRQEYLSSISGLEEVLVGRSKVMQKLREQVAKLARIDTNVIIYGETGC
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GKELVATSLHNESQRRAHHFVPINCGAIPETLFESELFGHEAGAFTGAAKKRIGKLEYAD
CHHHHHHHHCCHHHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
KGTLFFDEVESMPMSMQVKVLRALQEHTIERVGGNQQISVDLRVIAAAKEDLNDHDDFRQ
CCCEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEHHHCCCCHHHHHH
DLYYRLNVAQIYLPPLREREEDALILFEHFTLKNNPNCRPVSEADRKAILAYAWPGNVRE
HHHHEEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCHHH
LRNVAIRFALDNTISVMEILSSRPSSTNEETQAGVPLVIQLHNFERKVLHDSLVRNQGRI
HHHHHHEEEECCHHHHHHHHHCCCCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHCCCCE
TDVMVELDLPRRTLNQKMQKFGLNRSDYT
EEEEEEECCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]