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The map label for this gene is frp [H]

Identifier: 156977872

GI number: 156977872

Start: 1800473

End: 1801246

Strand: Direct

Name: frp [H]

Synonym: VIBHAR_06664

Alternate gene names: 156977872

Gene position: 1800473-1801246 (Clockwise)

Preceding gene: 156977869

Following gene: 156977873

Centisome position: 81.69

GC content: 45.74

Gene sequence:

>774_bases
ATGGTGAAGATTCAGCCAATACCAACAACAAGCCAAGGAAGTTTATTCATCATGAACAGTACGATTGAAACCATTCTCGG
TCATCGCTCTATTCGTAAGTTCACCTCTGAGCCAATTGCAAGTGAGCAACTACAAACGATTCTCCAATCGGGGTTAGCTG
CCTCTTCTTCGAGCATGCTGCAAGTCGTGTCGATCATTCGAGTAACAGATACAGAAAAGCGCAAACTGTTAGCGCAATAC
GCTGGCAATCAGACTTACGTTGAAAGTGCCGCAGAATTTTTGGTGTTTTGTATCGATTACCAGCGTCACGCCACTATCAA
CCCAGACGTTCAAGCCGACTTTACTGAATTGACTCTGATTGGTGCAGTGGACTCTGGCATCATGGCGCAAAACTGTTTAC
TTGCAGCCGAGTCTATGGGACTAGGTGGTGTATACATTGGTGGGTTAAGGAACAGCGCCGCACAAGTGGATGAACTGCTC
GGTTTACCTAAAAATACCGCCATTCTGTTTGGTATGTGCTTGGGTCACCCAGATCAAAGTCCAGAAACAAAGCCACGTCT
GCCAGCACATGTGATTGTTCATGAGAACCAATACCAAGCACTTAACATTGACGATGTACAAGCCTACGATAAAACCATGC
AAGAATACTACGCAAGCCGTACAAGTAATCAAAAACAGAGTGTATGGTCACAAGAAACCGCCGGAAAGCTAGCAGGAGAG
TCTCGCCCTCACATTCTGCCTTATTTGAATAGCAAGGGGTTGGCTAAACGCTAA

Upstream 100 bases:

>100_bases
ACGTCACTTTATGTTCGCATCATTATCTATGATTGTTATCTGTTACCCACTAGCACGAACTTGAGAGCTCTATTGGTTTA
CGCCCAATAGAAATAGCGTT

Downstream 100 bases:

>100_bases
TGATATAGTTCGCTAATCAAGAAAGATAAAAAAGGCCTCGTATGAGGCCTTTAGCATTTCTGCACATATTATTTGAATGA
AAATCCACTTTTGACACTAC

Product: nitroreductase A

Products: NA

Alternate protein names: Flavin reductase P; NADPH-FMN oxidoreductase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MVKIQPIPTTSQGSLFIMNSTIETILGHRSIRKFTSEPIASEQLQTILQSGLAASSSSMLQVVSIIRVTDTEKRKLLAQY
AGNQTYVESAAEFLVFCIDYQRHATINPDVQADFTELTLIGAVDSGIMAQNCLLAAESMGLGGVYIGGLRNSAAQVDELL
GLPKNTAILFGMCLGHPDQSPETKPRLPAHVIVHENQYQALNIDDVQAYDKTMQEYYASRTSNQKQSVWSQETAGKLAGE
SRPHILPYLNSKGLAKR

Sequences:

>Translated_257_residues
MVKIQPIPTTSQGSLFIMNSTIETILGHRSIRKFTSEPIASEQLQTILQSGLAASSSSMLQVVSIIRVTDTEKRKLLAQY
AGNQTYVESAAEFLVFCIDYQRHATINPDVQADFTELTLIGAVDSGIMAQNCLLAAESMGLGGVYIGGLRNSAAQVDELL
GLPKNTAILFGMCLGHPDQSPETKPRLPAHVIVHENQYQALNIDDVQAYDKTMQEYYASRTSNQKQSVWSQETAGKLAGE
SRPHILPYLNSKGLAKR
>Mature_257_residues
MVKIQPIPTTSQGSLFIMNSTIETILGHRSIRKFTSEPIASEQLQTILQSGLAASSSSMLQVVSIIRVTDTEKRKLLAQY
AGNQTYVESAAEFLVFCIDYQRHATINPDVQADFTELTLIGAVDSGIMAQNCLLAAESMGLGGVYIGGLRNSAAQVDELL
GLPKNTAILFGMCLGHPDQSPETKPRLPAHVIVHENQYQALNIDDVQAYDKTMQEYYASRTSNQKQSVWSQETAGKLAGE
SRPHILPYLNSKGLAKR

Specific function: Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin oxidoreductase frp family [H]

Homologues:

Organism=Escherichia coli, GI1787075, Length=240, Percent_Identity=51.6666666666667, Blast_Score=240, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016446
- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28115; Mature: 28115

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIQPIPTTSQGSLFIMNSTIETILGHRSIRKFTSEPIASEQLQTILQSGLAASSSSML
CEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHH
QVVSIIRVTDTEKRKLLAQYAGNQTYVESAAEFLVFCIDYQRHATINPDVQADFTELTLI
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHEEEE
GAVDSGIMAQNCLLAAESMGLGGVYIGGLRNSAAQVDELLGLPKNTAILFGMCLGHPDQS
ECCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCHHEEEEEECCCCCCC
PETKPRLPAHVIVHENQYQALNIDDVQAYDKTMQEYYASRTSNQKQSVWSQETAGKLAGE
CCCCCCCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
SRPHILPYLNSKGLAKR
CCCCEEEEECCCCCCCC
>Mature Secondary Structure
MVKIQPIPTTSQGSLFIMNSTIETILGHRSIRKFTSEPIASEQLQTILQSGLAASSSSML
CEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHH
QVVSIIRVTDTEKRKLLAQYAGNQTYVESAAEFLVFCIDYQRHATINPDVQADFTELTLI
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHEEEE
GAVDSGIMAQNCLLAAESMGLGGVYIGGLRNSAAQVDELLGLPKNTAILFGMCLGHPDQS
ECCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCHHEEEEEECCCCCCC
PETKPRLPAHVIVHENQYQALNIDDVQAYDKTMQEYYASRTSNQKQSVWSQETAGKLAGE
CCCCCCCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
SRPHILPYLNSKGLAKR
CCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8206832; 8885832 [H]