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The map label for this gene is pncB

Identifier: 156977787

GI number: 156977787

Start: 1722717

End: 1724027

Strand: Reverse

Name: pncB

Synonym: VIBHAR_06575

Alternate gene names: 156977787

Gene position: 1724027-1722717 (Counterclockwise)

Preceding gene: 156977790

Following gene: 156977785

Centisome position: 78.22

GC content: 45.08

Gene sequence:

>1311_bases
ATGACCACCAATTTATTTTCGTCTCGCATCATCCAAAGTGCGTTAGATTTTGACGTATACAAAGTGAATATGATGAGTGC
TGTTGCAGCGCTATATCCTGATGCGATGGTGTCTTATAAATTCATCGTACGCAGCGAAGAAGACCTGTCTGAATTACTGC
CAGAGGTGAAAGCTGAAGTACTTAAACTGCAAGACATCACTTTCTCCACTGAAGAAATCGAGTACATCAAAGGTGTTGCA
CCTTATCTAAACCCTGAGTTTGTTGATGCGCTGCACGCGTTTCGTTTTAATCCTCAACGTGACGTTTCTTTTAACATTAA
AACCATGGCAGATGGTACCAGCCAATTGCGCATTACCATCAATGGTCTTTGGAAAGAAACCATTCTCTACGAAACCATCA
TCATGAGTATTGTGTCCGAAGTGCGTAGTCGTGCACGTTGGGCAGAGGTTCCAGTCGAGCAATTCCAATCTGTTTTAGAA
GAGAAGGTTCGTCACCTTAAAACAGAACTGAAACGTCGCAATATCACCAACTTTAAGTTTGCCGATATGTCGACTCGTCG
TCGTTTCTCTTTCCAAGCGCAACGCTCAATGCTGAAGTATTTGAGCAAAGAGTTGCCTGACTGCCTGACAGGAACCAGCA
ACTACCACTTGGCGAAAGAGCTAGGTCTAACACCGATTGGTACTGTGGCACATGAATGGTTTATGGGTCATCAAGCATTG
GTGAATGTTCGTGATTCACAAAAGGTGGCTTTGCAACGCTGGCAAAAGATGTTTAACGGCGCGTTAGGTATCGCGTTAAC
GGACACTATTGGCATTGATGCGTTCTTAAAAGACTTTGATGAAGAACTCAGTAACGCGTACGTGGGAGTGCGCCATGATA
GTGGCTGCCCTTACACATGGGGCGAGAAGATGATCGAGCATTACCAATCGCTTGGCATCGACCCAATGACGAAAACCTTA
GTGTTTACCGATGGTTTGAACTTCGAGCAAGCACTGGCTATTTGTGAGCACTTCCAAGATCGTGTTCAAGTGAGTTTTGG
TATTGGTACGTCACTAGCGAACGACATGGGTGATTACGCAAACGCGCAAGGCATCGCATACAAGCCACTGTCTATTGTGA
TTAAGATGGTGTCATGCAATGGCTCACCAGTTGCTAAAATCAGTGATGAGCCAGAGAAAGCGATGTGCGAAGACATCTTC
TTTTTAATGAATTTGAAGCGTCGTTTTGAGCAGCCACTTGATCTTGACGAGTGCCGTGGACTGATCGACCGTCTAGAGGA
TGAAGGAGATAATTACCTCATCGACGCCTGA

Upstream 100 bases:

>100_bases
AACTTTCCACCTACTTGGTTGGGAAAACAATAAGATGCGGTTTGTACCGTGCTGAGGGAATTTGGGTATAAACGAAAAAG
GGCGTGTAGAAGGGCTCCGA

Downstream 100 bases:

>100_bases
TAAGAGAAGTGAATGATTGATAAAAAGAGTGGTGCAAATGCATCACTCTTTTTGTGCCTCACAAACTTCGTTATATTTGA
TCTCGCACAGTGCCCCACAC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTTNLFSSRIIQSALDFDVYKVNMMSAVAALYPDAMVSYKFIVRSEEDLSELLPEVKAEVLKLQDITFSTEEIEYIKGVA
PYLNPEFVDALHAFRFNPQRDVSFNIKTMADGTSQLRITINGLWKETILYETIIMSIVSEVRSRARWAEVPVEQFQSVLE
EKVRHLKTELKRRNITNFKFADMSTRRRFSFQAQRSMLKYLSKELPDCLTGTSNYHLAKELGLTPIGTVAHEWFMGHQAL
VNVRDSQKVALQRWQKMFNGALGIALTDTIGIDAFLKDFDEELSNAYVGVRHDSGCPYTWGEKMIEHYQSLGIDPMTKTL
VFTDGLNFEQALAICEHFQDRVQVSFGIGTSLANDMGDYANAQGIAYKPLSIVIKMVSCNGSPVAKISDEPEKAMCEDIF
FLMNLKRRFEQPLDLDECRGLIDRLEDEGDNYLIDA

Sequences:

>Translated_436_residues
MTTNLFSSRIIQSALDFDVYKVNMMSAVAALYPDAMVSYKFIVRSEEDLSELLPEVKAEVLKLQDITFSTEEIEYIKGVA
PYLNPEFVDALHAFRFNPQRDVSFNIKTMADGTSQLRITINGLWKETILYETIIMSIVSEVRSRARWAEVPVEQFQSVLE
EKVRHLKTELKRRNITNFKFADMSTRRRFSFQAQRSMLKYLSKELPDCLTGTSNYHLAKELGLTPIGTVAHEWFMGHQAL
VNVRDSQKVALQRWQKMFNGALGIALTDTIGIDAFLKDFDEELSNAYVGVRHDSGCPYTWGEKMIEHYQSLGIDPMTKTL
VFTDGLNFEQALAICEHFQDRVQVSFGIGTSLANDMGDYANAQGIAYKPLSIVIKMVSCNGSPVAKISDEPEKAMCEDIF
FLMNLKRRFEQPLDLDECRGLIDRLEDEGDNYLIDA
>Mature_435_residues
TTNLFSSRIIQSALDFDVYKVNMMSAVAALYPDAMVSYKFIVRSEEDLSELLPEVKAEVLKLQDITFSTEEIEYIKGVAP
YLNPEFVDALHAFRFNPQRDVSFNIKTMADGTSQLRITINGLWKETILYETIIMSIVSEVRSRARWAEVPVEQFQSVLEE
KVRHLKTELKRRNITNFKFADMSTRRRFSFQAQRSMLKYLSKELPDCLTGTSNYHLAKELGLTPIGTVAHEWFMGHQALV
NVRDSQKVALQRWQKMFNGALGIALTDTIGIDAFLKDFDEELSNAYVGVRHDSGCPYTWGEKMIEHYQSLGIDPMTKTLV
FTDGLNFEQALAICEHFQDRVQVSFGIGTSLANDMGDYANAQGIAYKPLSIVIKMVSCNGSPVAKISDEPEKAMCEDIFF
LMNLKRRFEQPLDLDECRGLIDRLEDEGDNYLIDA

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family

Homologues:

Organism=Escherichia coli, GI1787162, Length=408, Percent_Identity=39.9509803921569, Blast_Score=313, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6324783, Length=409, Percent_Identity=34.4743276283619, Blast_Score=216, Evalue=8e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PNCB_VIBHB (A7N4I5)

Other databases:

- EMBL:   CP000790
- RefSeq:   YP_001448693.1
- ProteinModelPortal:   A7N4I5
- SMR:   A7N4I5
- STRING:   A7N4I5
- GeneID:   5558570
- GenomeReviews:   CP000790_GR
- KEGG:   vha:VIBHAR_06575
- NMPDR:   fig|338187.4.peg.3900
- eggNOG:   COG1488
- HOGENOM:   HBG325503
- OMA:   GNTFYGK
- ProtClustDB:   PRK05321
- GO:   GO:0005737
- HAMAP:   MF_00570
- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638
- PANTHER:   PTHR11098:SF1
- PIRSF:   PIRSF000484
- TIGRFAMs:   TIGR01514

Pfam domain/function: PF04095 NAPRTase; SSF51690 Q_phspho_trans

EC number: =2.4.2.11

Molecular weight: Translated: 49687; Mature: 49556

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNLFSSRIIQSALDFDVYKVNMMSAVAALYPDAMVSYKFIVRSEEDLSELLPEVKAEV
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHEECCHHHHHHHHHHHHHHH
LKLQDITFSTEEIEYIKGVAPYLNPEFVDALHAFRFNPQRDVSFNIKTMADGTSQLRITI
HHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEE
NGLWKETILYETIIMSIVSEVRSRARWAEVPVEQFQSVLEEKVRHLKTELKRRNITNFKF
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
ADMSTRRRFSFQAQRSMLKYLSKELPDCLTGTSNYHLAKELGLTPIGTVAHEWFMGHQAL
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHCCCCCHHHHHHHHHHCCHHH
VNVRDSQKVALQRWQKMFNGALGIALTDTIGIDAFLKDFDEELSNAYVGVRHDSGCPYTW
EECCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
GEKMIEHYQSLGIDPMTKTLVFTDGLNFEQALAICEHFQDRVQVSFGIGTSLANDMGDYA
HHHHHHHHHHCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHC
NAQGIAYKPLSIVIKMVSCNGSPVAKISDEPEKAMCEDIFFLMNLKRRFEQPLDLDECRG
CCCCCEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LIDRLEDEGDNYLIDA
HHHHHHCCCCCEEECC
>Mature Secondary Structure 
TTNLFSSRIIQSALDFDVYKVNMMSAVAALYPDAMVSYKFIVRSEEDLSELLPEVKAEV
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHEECCHHHHHHHHHHHHHHH
LKLQDITFSTEEIEYIKGVAPYLNPEFVDALHAFRFNPQRDVSFNIKTMADGTSQLRITI
HHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEE
NGLWKETILYETIIMSIVSEVRSRARWAEVPVEQFQSVLEEKVRHLKTELKRRNITNFKF
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
ADMSTRRRFSFQAQRSMLKYLSKELPDCLTGTSNYHLAKELGLTPIGTVAHEWFMGHQAL
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHCCCCCHHHHHHHHHHCCHHH
VNVRDSQKVALQRWQKMFNGALGIALTDTIGIDAFLKDFDEELSNAYVGVRHDSGCPYTW
EECCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
GEKMIEHYQSLGIDPMTKTLVFTDGLNFEQALAICEHFQDRVQVSFGIGTSLANDMGDYA
HHHHHHHHHHCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHC
NAQGIAYKPLSIVIKMVSCNGSPVAKISDEPEKAMCEDIFFLMNLKRRFEQPLDLDECRG
CCCCCEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LIDRLEDEGDNYLIDA
HHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA