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The map label for this gene is mcpB [H]

Identifier: 156977526

GI number: 156977526

Start: 1490103

End: 1491974

Strand: Direct

Name: mcpB [H]

Synonym: VIBHAR_06314

Alternate gene names: 156977526

Gene position: 1490103-1491974 (Clockwise)

Preceding gene: 156977525

Following gene: 156977528

Centisome position: 67.61

GC content: 47.22

Gene sequence:

>1872_bases
ATGAAATTTAGACATAAGGTTGTCACCGCCTCTTCTATTTTATTGCTTGTGACTGTGGCGTTGCTGTCGACACAACAAGT
TATGACTATCCGTTCACAGATCGAAGAAAACATCGATACCAGTGTGAGTGAGATCCTATCCAGTGTGGGGAACACGGTAG
AATCGGAAATGAACGCTAAGAAAGAACTCGCTCAATCCATGACTGAGATTCTTGAAATTAACCCAAGCGACCACGGTTAC
GTGAAAGATGTGCTAGAGAAACCAATGCCAAAATCAAGCTTCTTGGCCATAGGTTATGCTTACGACAGCAACGGATTCGT
GATTGAAAACGATGATGGTTGGGAAGCCAGTCCAGATTACGACCCTCGTGTTCGCCCTTGGTTTGTTTCAGCAAAAGCAC
AAGGCAAACTCGTCGTAACGGATCCATACGTCGACGTTTCTTCTAAGAAAGTGATCATCTCTATCGGTACTCCAGTGCGC
GAAGCTGGCCAGTTCCTCGCAGCCATGTTTTACGATATGGAGCTAACCACCCTTTCTGACTTGGTTAACCAAGTAAACCT
ATTTGATGCGGGTTACCTTTTCCTAGTAACGGCAGATGGCACGACGATCGCGCACCCAGAAGCCAAATACAACGGCGAGA
AGCTCTCAAGCTACCTACCACAAGTAGAGCTAGCATCAGGAGCTCAGCACATCGAGATGAACGGCGACAAATTCATGGTC
AGCCTAACCCACATCCCAAGTGAAAACTGGTATGTAGGTGCAGTTGTTGATGAGAGCATTGCGTATGCTGCAGTAGGTAA
GCTGCGTAATAGCGCAATCATCTACTCATTGATTGCTGTGATTGCCTCTATCATTGCGCTGACTATCCTTATCCGTACCT
TGATGCGCCCTCTTGATGAGCTAAACACTGCAATCCAAGCTGTAGCATCAGGCAAAGGCGATTTGACGCAGCGCTTGGAT
ACCAACACAGATCAAGAATTCTCTGAGCTGGCAAAAGGTTTCAACACCTTTATGGAGAACTTGCAGCATCAAATCATCGA
ATCGAAGAGCATTTCTGATCAGATCCTAAGTGGCACGCAAATCACCGCTGAAGGCGCTCGTGATTCTGCTTCTGCAATTC
AAACTCAGCTTCAAGAGCTTGAACAGTTGGCGACAGCAATGCACGAGATGTCGGTAACGGCAACAGAAGTTGCTAACAAC
GCACAAGGCGCAGCAAGTGCAGCGAAAGAAGCGGACGAAGCGACAGTGCAAGGTTCTTCTATCGTGAATGAGTCGACTGA
GACGATTAACCTACTGTCAGACAGCATCGATCAAGCGGTAGAGGAAGTACAAGGTCTTGAGTCAGCAACAGCAAATATCG
AGACGATCCTAAAAGTGATCAACGATATCGCAGACCAAACTAACCTACTGGCACTAAACGCAGCAATCGAGGCAGCCCGT
GCGGGAGAATCTGGTCGTGGCTTTGCCGTTGTAGCGGATGAAGTTCGTACACTGGCGCAACGTACTCAAGAATCTACTAC
AGAAATCCGTAGCATGATTGAGCAGCTTCAATCTGGCGCTTCCTCTGTTGCAAGTGCTATGCACCAGAGCAAAGGCAGTG
CAGTAGAAGCGGTAGAGAAAGCAGAACACGCCAATGACGCTCTACAACGTATCCGCGATGCGATTCAACGTATCTCTGAT
ATGAACCTACAAATTGCGTCAGCAGCAGAAGAACAAAGCTTAGTAGCAGAAGAAATCAACAACAACACGGTTAACATTAA
AGACCTGTCGACCCAAGTTGCTGATTCAGCGAACCGCACCAACGATGCAATGCAAGCACAGCATGAAGACGTTCGTAAGC
AAGATGAGATCCTAAACCGCTTTACGGTTTAA

Upstream 100 bases:

>100_bases
GTTGATTCGGTATATAGTGTGTTCACTTCTGCCGAATGTACCCAACAAAATAAGAGGTACAAGCAGAGTAAACCAGCCGG
GAGACTCGAGAGGAAAAAAT

Downstream 100 bases:

>100_bases
CTTCTCCTTTTTAACCCAGAACAAACTTCATCAAACAACAAGCAAAACAGCGAGCCAAAGTGCTCGCTGTTTTTTGTTTA
CAAAGCCACGTGTATATAAC

Product: histidine kinase

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MKFRHKVVTASSILLLVTVALLSTQQVMTIRSQIEENIDTSVSEILSSVGNTVESEMNAKKELAQSMTEILEINPSDHGY
VKDVLEKPMPKSSFLAIGYAYDSNGFVIENDDGWEASPDYDPRVRPWFVSAKAQGKLVVTDPYVDVSSKKVIISIGTPVR
EAGQFLAAMFYDMELTTLSDLVNQVNLFDAGYLFLVTADGTTIAHPEAKYNGEKLSSYLPQVELASGAQHIEMNGDKFMV
SLTHIPSENWYVGAVVDESIAYAAVGKLRNSAIIYSLIAVIASIIALTILIRTLMRPLDELNTAIQAVASGKGDLTQRLD
TNTDQEFSELAKGFNTFMENLQHQIIESKSISDQILSGTQITAEGARDSASAIQTQLQELEQLATAMHEMSVTATEVANN
AQGAASAAKEADEATVQGSSIVNESTETINLLSDSIDQAVEEVQGLESATANIETILKVINDIADQTNLLALNAAIEAAR
AGESGRGFAVVADEVRTLAQRTQESTTEIRSMIEQLQSGASSVASAMHQSKGSAVEAVEKAEHANDALQRIRDAIQRISD
MNLQIASAAEEQSLVAEEINNNTVNIKDLSTQVADSANRTNDAMQAQHEDVRKQDEILNRFTV

Sequences:

>Translated_623_residues
MKFRHKVVTASSILLLVTVALLSTQQVMTIRSQIEENIDTSVSEILSSVGNTVESEMNAKKELAQSMTEILEINPSDHGY
VKDVLEKPMPKSSFLAIGYAYDSNGFVIENDDGWEASPDYDPRVRPWFVSAKAQGKLVVTDPYVDVSSKKVIISIGTPVR
EAGQFLAAMFYDMELTTLSDLVNQVNLFDAGYLFLVTADGTTIAHPEAKYNGEKLSSYLPQVELASGAQHIEMNGDKFMV
SLTHIPSENWYVGAVVDESIAYAAVGKLRNSAIIYSLIAVIASIIALTILIRTLMRPLDELNTAIQAVASGKGDLTQRLD
TNTDQEFSELAKGFNTFMENLQHQIIESKSISDQILSGTQITAEGARDSASAIQTQLQELEQLATAMHEMSVTATEVANN
AQGAASAAKEADEATVQGSSIVNESTETINLLSDSIDQAVEEVQGLESATANIETILKVINDIADQTNLLALNAAIEAAR
AGESGRGFAVVADEVRTLAQRTQESTTEIRSMIEQLQSGASSVASAMHQSKGSAVEAVEKAEHANDALQRIRDAIQRISD
MNLQIASAAEEQSLVAEEINNNTVNIKDLSTQVADSANRTNDAMQAQHEDVRKQDEILNRFTV
>Mature_623_residues
MKFRHKVVTASSILLLVTVALLSTQQVMTIRSQIEENIDTSVSEILSSVGNTVESEMNAKKELAQSMTEILEINPSDHGY
VKDVLEKPMPKSSFLAIGYAYDSNGFVIENDDGWEASPDYDPRVRPWFVSAKAQGKLVVTDPYVDVSSKKVIISIGTPVR
EAGQFLAAMFYDMELTTLSDLVNQVNLFDAGYLFLVTADGTTIAHPEAKYNGEKLSSYLPQVELASGAQHIEMNGDKFMV
SLTHIPSENWYVGAVVDESIAYAAVGKLRNSAIIYSLIAVIASIIALTILIRTLMRPLDELNTAIQAVASGKGDLTQRLD
TNTDQEFSELAKGFNTFMENLQHQIIESKSISDQILSGTQITAEGARDSASAIQTQLQELEQLATAMHEMSVTATEVANN
AQGAASAAKEADEATVQGSSIVNESTETINLLSDSIDQAVEEVQGLESATANIETILKVINDIADQTNLLALNAAIEAAR
AGESGRGFAVVADEVRTLAQRTQESTTEIRSMIEQLQSGASSVASAMHQSKGSAVEAVEKAEHANDALQRIRDAIQRISD
MNLQIASAAEEQSLVAEEINNNTVNIKDLSTQVADSANRTNDAMQAQHEDVRKQDEILNRFTV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=302, Percent_Identity=33.112582781457, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788195, Length=282, Percent_Identity=33.6879432624113, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1787690, Length=301, Percent_Identity=31.5614617940199, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1788194, Length=312, Percent_Identity=29.4871794871795, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789453, Length=260, Percent_Identity=31.5384615384615, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 67484; Mature: 67484

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRHKVVTASSILLLVTVALLSTQQVMTIRSQIEENIDTSVSEILSSVGNTVESEMNAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELAQSMTEILEINPSDHGYVKDVLEKPMPKSSFLAIGYAYDSNGFVIENDDGWEASPDY
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCCCCCCC
DPRVRPWFVSAKAQGKLVVTDPYVDVSSKKVIISIGTPVREAGQFLAAMFYDMELTTLSD
CCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LVNQVNLFDAGYLFLVTADGTTIAHPEAKYNGEKLSSYLPQVELASGAQHIEMNGDKFMV
HHHHHHHCCCCEEEEEEECCCEECCCCCCCCHHHHHHHCCCHHHHCCCCEEEECCCEEEE
SLTHIPSENWYVGAVVDESIAYAAVGKLRNSAIIYSLIAVIASIIALTILIRTLMRPLDE
EEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNTAIQAVASGKGDLTQRLDTNTDQEFSELAKGFNTFMENLQHQIIESKSISDQILSGTQ
HHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCE
ITAEGARDSASAIQTQLQELEQLATAMHEMSVTATEVANNAQGAASAAKEADEATVQGSS
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCH
IVNESTETINLLSDSIDQAVEEVQGLESATANIETILKVINDIADQTNLLALNAAIEAAR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
AGESGRGFAVVADEVRTLAQRTQESTTEIRSMIEQLQSGASSVASAMHQSKGSAVEAVEK
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AEHANDALQRIRDAIQRISDMNLQIASAAEEQSLVAEEINNNTVNIKDLSTQVADSANRT
HHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCC
NDAMQAQHEDVRKQDEILNRFTV
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFRHKVVTASSILLLVTVALLSTQQVMTIRSQIEENIDTSVSEILSSVGNTVESEMNAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELAQSMTEILEINPSDHGYVKDVLEKPMPKSSFLAIGYAYDSNGFVIENDDGWEASPDY
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCCCCCCC
DPRVRPWFVSAKAQGKLVVTDPYVDVSSKKVIISIGTPVREAGQFLAAMFYDMELTTLSD
CCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LVNQVNLFDAGYLFLVTADGTTIAHPEAKYNGEKLSSYLPQVELASGAQHIEMNGDKFMV
HHHHHHHCCCCEEEEEEECCCEECCCCCCCCHHHHHHHCCCHHHHCCCCEEEECCCEEEE
SLTHIPSENWYVGAVVDESIAYAAVGKLRNSAIIYSLIAVIASIIALTILIRTLMRPLDE
EEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNTAIQAVASGKGDLTQRLDTNTDQEFSELAKGFNTFMENLQHQIIESKSISDQILSGTQ
HHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCE
ITAEGARDSASAIQTQLQELEQLATAMHEMSVTATEVANNAQGAASAAKEADEATVQGSS
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCH
IVNESTETINLLSDSIDQAVEEVQGLESATANIETILKVINDIADQTNLLALNAAIEAAR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
AGESGRGFAVVADEVRTLAQRTQESTTEIRSMIEQLQSGASSVASAMHQSKGSAVEAVEK
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AEHANDALQRIRDAIQRISDMNLQIASAAEEQSLVAEEINNNTVNIKDLSTQVADSANRT
HHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCC
NDAMQAQHEDVRKQDEILNRFTV
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]