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The map label for this gene is aer [H]

Identifier: 156977471

GI number: 156977471

Start: 1439389

End: 1440951

Strand: Reverse

Name: aer [H]

Synonym: VIBHAR_06258

Alternate gene names: 156977471

Gene position: 1440951-1439389 (Counterclockwise)

Preceding gene: 156977472

Following gene: 156977468

Centisome position: 65.38

GC content: 45.81

Gene sequence:

>1563_bases
ATGTCAGCCTTAACTTCCAATAAAGCTCAAGAAACTCTCGTAGGAGATTCTGACGAACTGGTCTCCACTACCGATCTCAA
AGGTGTTATCACTTATTGCAATGATGCATTTTGCAGAATCGCTGAATACAGTCACGATGAACTGCTCGGACAAAACCACA
ATGTCGTACGCCATGGTGACATGCCTAAAGCGGCATTCGGTGATATGTGGACTCGTCTAAAACAAGGCAAAGCGTGGCGC
GGAATTGTAAAAAATAGCACGAAGTCGGGTGGATATTACTGGGTGGATGCTTATGTAACGCCCATTTATGAAGGCCACCA
AGTTGTGGGATATCAGTCGGTTCGTGTAAAGCCAAAGCGAGAGTGGGTGGACATTGCTTCTCAAGCATATCAGGGCTTAT
TGAAGGCTGAAAAATCTGGCCGTGCTTGGACCTTGAAACTGAGTGATACGTTGCGTTATGCGATTCTACTTGGTGCGCTT
GCGGCACCAACAGCTGGCTTCGCTTTTTCACTTGAAGGACCTTTGGCTTGGCTTGCGACATTGCTCCCGGCTGGGGTGCT
CGCAATGTTGTTCCGCCAAGAGCTTATTGATACACCACTGCAATTTAAAAAGCTGCAAACCCAATACGATAGCGTGAGTC
GTTTAGTGTATTCAGGTAATAAACCGTTCTCGATTGCAGATTTTCATATAAAGATGCTCTCTGCTCGTATTCGTACTGTC
CTTGGACGTATGACAGATTCAGCTGTGCCATTACAAAACTGTGCTGAAGAGTTGAGTCACACAACGGCAGAAGTCTTGTC
TGCACTGACTCAGCAAAACAACGATATTCACGAGGTTCGTGACGCGGCCGATTCAATGGAAGCATCTGCCAATTCAGTAT
CATCTAGTTCTCATGAAGCCCATGTATTGATTGATGACACTTTGAAATCTTGTTTGATGGCGAAAGACACGATTGATCAA
ACTCATACTAACCTAGCGCAGCTTAGTTTACAGGCGGAGAAAGCCACAGAGACGACTTATCAACTGAGTGATCAAGCGCA
GAAGGTAAGTCAATTAATGGAGGAGATAGGTGGTATTGCCGATCAAACGAATCTGCTAGCGCTTAATGCAGCAATTGAAG
CAGCACGAGCGGGTGAACAAGGTCGCGGCTTCGCTGTGGTTGCCGATGAAGTGAGAGCGCTATCTGGACGGACTTCGAAT
GCAACTGAGCAAATTAAAGCATCCATTGAAACCATGTTGATGACGATTCAGGGCTGGCAGAAAGACATTATCGCTAACAA
AGATCAAACGGATACATGCTCACAAGTTGCAGAGCAAAGTGCGTTGCGTTTGTCGGAAGTAGAGCAGATGATGCAAACCA
TGAATGGGTTGATGGTGAATGTCGCGGATTCTGCCAATAAGCAACTGCAACTGTCTAGCAATGTGAATCAACACATTCAT
TCGATTGCTTCTACCGCAGAGCAGAACTTGGCCGCGACATATTCTGTAGAGCAAAACAGTAAGCAGTTAAAAGAGCAGGT
TCAAGACTTCTACCGACTTGCGAATCAGTTTGAAGAGAAGTGA

Upstream 100 bases:

>100_bases
AAATGTCGCATCAGTAAGGTTTTTTCTCTAGCATTTTGTAATAAATATAACAATTGTGTATATATCCTGTCGCAATTTAA
TAACTACAGAAGCCTCATCT

Downstream 100 bases:

>100_bases
TACGAACTAGAACTAGATCGTTGAATCATTGTTCAAAATGAACAGATAAAATAAAGCCCCGCTACAGAGAGCGGGGCTTT
TCAGTTTTCAAATTCGCAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSALTSNKAQETLVGDSDELVSTTDLKGVITYCNDAFCRIAEYSHDELLGQNHNVVRHGDMPKAAFGDMWTRLKQGKAWR
GIVKNSTKSGGYYWVDAYVTPIYEGHQVVGYQSVRVKPKREWVDIASQAYQGLLKAEKSGRAWTLKLSDTLRYAILLGAL
AAPTAGFAFSLEGPLAWLATLLPAGVLAMLFRQELIDTPLQFKKLQTQYDSVSRLVYSGNKPFSIADFHIKMLSARIRTV
LGRMTDSAVPLQNCAEELSHTTAEVLSALTQQNNDIHEVRDAADSMEASANSVSSSSHEAHVLIDDTLKSCLMAKDTIDQ
THTNLAQLSLQAEKATETTYQLSDQAQKVSQLMEEIGGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSGRTSN
ATEQIKASIETMLMTIQGWQKDIIANKDQTDTCSQVAEQSALRLSEVEQMMQTMNGLMVNVADSANKQLQLSSNVNQHIH
SIASTAEQNLAATYSVEQNSKQLKEQVQDFYRLANQFEEK

Sequences:

>Translated_520_residues
MSALTSNKAQETLVGDSDELVSTTDLKGVITYCNDAFCRIAEYSHDELLGQNHNVVRHGDMPKAAFGDMWTRLKQGKAWR
GIVKNSTKSGGYYWVDAYVTPIYEGHQVVGYQSVRVKPKREWVDIASQAYQGLLKAEKSGRAWTLKLSDTLRYAILLGAL
AAPTAGFAFSLEGPLAWLATLLPAGVLAMLFRQELIDTPLQFKKLQTQYDSVSRLVYSGNKPFSIADFHIKMLSARIRTV
LGRMTDSAVPLQNCAEELSHTTAEVLSALTQQNNDIHEVRDAADSMEASANSVSSSSHEAHVLIDDTLKSCLMAKDTIDQ
THTNLAQLSLQAEKATETTYQLSDQAQKVSQLMEEIGGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSGRTSN
ATEQIKASIETMLMTIQGWQKDIIANKDQTDTCSQVAEQSALRLSEVEQMMQTMNGLMVNVADSANKQLQLSSNVNQHIH
SIASTAEQNLAATYSVEQNSKQLKEQVQDFYRLANQFEEK
>Mature_519_residues
SALTSNKAQETLVGDSDELVSTTDLKGVITYCNDAFCRIAEYSHDELLGQNHNVVRHGDMPKAAFGDMWTRLKQGKAWRG
IVKNSTKSGGYYWVDAYVTPIYEGHQVVGYQSVRVKPKREWVDIASQAYQGLLKAEKSGRAWTLKLSDTLRYAILLGALA
APTAGFAFSLEGPLAWLATLLPAGVLAMLFRQELIDTPLQFKKLQTQYDSVSRLVYSGNKPFSIADFHIKMLSARIRTVL
GRMTDSAVPLQNCAEELSHTTAEVLSALTQQNNDIHEVRDAADSMEASANSVSSSSHEAHVLIDDTLKSCLMAKDTIDQT
HTNLAQLSLQAEKATETTYQLSDQAQKVSQLMEEIGGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSGRTSNA
TEQIKASIETMLMTIQGWQKDIIANKDQTDTCSQVAEQSALRLSEVEQMMQTMNGLMVNVADSANKQLQLSSNVNQHIHS
IASTAEQNLAATYSVEQNSKQLKEQVQDFYRLANQFEEK

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=456, Percent_Identity=33.9912280701754, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI2367378, Length=238, Percent_Identity=29.8319327731092, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788195, Length=199, Percent_Identity=33.1658291457286, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788194, Length=323, Percent_Identity=28.1733746130031, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787690, Length=184, Percent_Identity=34.7826086956522, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57180; Mature: 57049

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALTSNKAQETLVGDSDELVSTTDLKGVITYCNDAFCRIAEYSHDELLGQNHNVVRHGD
CCCCCCCCHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEECCC
MPKAAFGDMWTRLKQGKAWRGIVKNSTKSGGYYWVDAYVTPIYEGHQVVGYQSVRVKPKR
CCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEECCCHH
EWVDIASQAYQGLLKAEKSGRAWTLKLSDTLRYAILLGALAAPTAGFAFSLEGPLAWLAT
HHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHH
LLPAGVLAMLFRQELIDTPLQFKKLQTQYDSVSRLVYSGNKPFSIADFHIKMLSARIRTV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHH
LGRMTDSAVPLQNCAEELSHTTAEVLSALTQQNNDIHEVRDAADSMEASANSVSSSSHEA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
HVLIDDTLKSCLMAKDTIDQTHTNLAQLSLQAEKATETTYQLSDQAQKVSQLMEEIGGIA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSGRTSNATEQIKASIETMLMTIQGWQ
CCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
KDIIANKDQTDTCSQVAEQSALRLSEVEQMMQTMNGLMVNVADSANKQLQLSSNVNQHIH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHH
SIASTAEQNLAATYSVEQNSKQLKEQVQDFYRLANQFEEK
HHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SALTSNKAQETLVGDSDELVSTTDLKGVITYCNDAFCRIAEYSHDELLGQNHNVVRHGD
CCCCCCCHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEECCC
MPKAAFGDMWTRLKQGKAWRGIVKNSTKSGGYYWVDAYVTPIYEGHQVVGYQSVRVKPKR
CCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEECCCHH
EWVDIASQAYQGLLKAEKSGRAWTLKLSDTLRYAILLGALAAPTAGFAFSLEGPLAWLAT
HHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHH
LLPAGVLAMLFRQELIDTPLQFKKLQTQYDSVSRLVYSGNKPFSIADFHIKMLSARIRTV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHH
LGRMTDSAVPLQNCAEELSHTTAEVLSALTQQNNDIHEVRDAADSMEASANSVSSSSHEA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
HVLIDDTLKSCLMAKDTIDQTHTNLAQLSLQAEKATETTYQLSDQAQKVSQLMEEIGGIA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSGRTSNATEQIKASIETMLMTIQGWQ
CCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
KDIIANKDQTDTCSQVAEQSALRLSEVEQMMQTMNGLMVNVADSANKQLQLSSNVNQHIH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHH
SIASTAEQNLAATYSVEQNSKQLKEQVQDFYRLANQFEEK
HHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]