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The map label for this gene is cueR [H]

Identifier: 156977345

GI number: 156977345

Start: 1311809

End: 1312195

Strand: Direct

Name: cueR [H]

Synonym: VIBHAR_06131

Alternate gene names: 156977345

Gene position: 1311809-1312195 (Clockwise)

Preceding gene: 156977344

Following gene: 156977350

Centisome position: 59.52

GC content: 43.93

Gene sequence:

>387_bases
ATGAATATTGGTGCAGTTGCAAAACTCACAGGATTGTCTTCTAAATCGATTCGTATGTACGAAGACAAAGGCATCATTTC
TTCACCAGCTCGCAGTGACTCAGGCTATCGTGAATATTCTGAAAAACACATCCAAGAGTTAAACCTTGTTTCCAGAGCAA
AAAACGCCGGTTTCTCATTACAAGAATGCAAAGAGTTCGTGCAATTGGCACACAACCCAAACCGCAAAAGTAGCGAAGTA
AAAGCACGAACCATGGACAAACTTCATGAAGTGGAGCAAAAAATTGCCCACTTATTGGAGATGAAAAAGCAGTTGGAGGG
CTGGGTTTCTTCATGTCCTGGGGATGCAAAGAGCCGCTGCCCGATCATGGACGAGCTCACCAAGTAA

Upstream 100 bases:

>100_bases
CACAGAATCGACAGACGAAAAACAGCATTAAAGTCGTTTTTGAACACCAACACTTAGCGTTATACTCGCGAGAAAGGTTA
TCTGAAACACAGAGGTCATC

Downstream 100 bases:

>100_bases
ACTCGTCACTATTTCTACTTCATCTTGCTGGACTATTGTTTTGATGAGCTCTGCTTTAACGGAATTTTGGTCAATAGAAC
CTAACTTTAATGGTAAGTGC

Product: Zn(II)-responsive regulator of ZntA

Products: NA

Alternate protein names: Copper efflux regulator; Copper export regulator [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MNIGAVAKLTGLSSKSIRMYEDKGIISSPARSDSGYREYSEKHIQELNLVSRAKNAGFSLQECKEFVQLAHNPNRKSSEV
KARTMDKLHEVEQKIAHLLEMKKQLEGWVSSCPGDAKSRCPIMDELTK

Sequences:

>Translated_128_residues
MNIGAVAKLTGLSSKSIRMYEDKGIISSPARSDSGYREYSEKHIQELNLVSRAKNAGFSLQECKEFVQLAHNPNRKSSEV
KARTMDKLHEVEQKIAHLLEMKKQLEGWVSSCPGDAKSRCPIMDELTK
>Mature_128_residues
MNIGAVAKLTGLSSKSIRMYEDKGIISSPARSDSGYREYSEKHIQELNLVSRAKNAGFSLQECKEFVQLAHNPNRKSSEV
KARTMDKLHEVEQKIAHLLEMKKQLEGWVSSCPGDAKSRCPIMDELTK

Specific function: Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=46.4566929133858, Blast_Score=137, Evalue=3e-34,
Organism=Escherichia coli, GI1789687, Length=128, Percent_Identity=31.25, Blast_Score=75, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14395; Mature: 14395

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGAVAKLTGLSSKSIRMYEDKGIISSPARSDSGYREYSEKHIQELNLVSRAKNAGFSL
CCCCCHHHHHCCCCCCEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
QECKEFVQLAHNPNRKSSEVKARTMDKLHEVEQKIAHLLEMKKQLEGWVSSCPGDAKSRC
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PIMDELTK
CCHHHHCC
>Mature Secondary Structure
MNIGAVAKLTGLSSKSIRMYEDKGIISSPARSDSGYREYSEKHIQELNLVSRAKNAGFSL
CCCCCHHHHHCCCCCCEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
QECKEFVQLAHNPNRKSSEVKARTMDKLHEVEQKIAHLLEMKKQLEGWVSSCPGDAKSRC
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PIMDELTK
CCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA