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The map label for this gene is atpA2

Identifier: 156977320

GI number: 156977320

Start: 1268479

End: 1270017

Strand: Reverse

Name: atpA2

Synonym: VIBHAR_06106

Alternate gene names: 156977320

Gene position: 1270017-1268479 (Counterclockwise)

Preceding gene: 156977321

Following gene: 156977319

Centisome position: 57.62

GC content: 48.99

Gene sequence:

>1539_bases
ATGCAATTAAATTCAAATGAAATCAGTGAATTAATCAGAGAGCGAATTGTTAACTTCAACCTCGAAAGTGAAGCGAGAAA
TGAAGGTACTATCGTCTCTGTGAGTGACGGCATCATCACAATTCACGGTCTTGCAGATGTTATGCAAGGCGAGATGCTAG
AACTGCCAAATAACCGCTTCGCGTTGGCACTTAACTTAGAGCGTCATTCCGTCGGCGCGGTTGTGATGGGTCCATATGCG
GACTTGTCAGAAGGGATGAAAGTAAAAGGCACCGGTCGTATTCTTGAAGTGCCAGTCGGCAACGGTTTGCTAGGTCGCGT
AGTGAACACGCTAGGTCAACCAATCGATGGTAAAGGCGCAGTGTCATTCGATCGTATGGACCCTGTTGAAGTGATTGCCC
CTGGTGTTATCGACCGTAAGTCTGTCGATCAGCCAATCCAAACCGGTTACAAAGCGGTAGACTCCATGGTGCCAATCGGT
CGTGGTCAGCGTGAGTTGATCATCGGTGACCGTCAGACAGGTAAAACCGCGATGGCGATTGATGCCATCATCAACCAAAA
AGAACTGGGCGTTAAATGTATTTACGTCGCAATTGGTCAAAAAGCATCGACCATTGCCAACGTGGTTCGCAAACTAGAAG
AGCACGGTGCACTAGAAAACACCATTGTTGTGGTTGCATCAGCATCAGAAGCGGCAGCGCTGCAATACCTCGCGCCATAC
GCAGGTTGTACCATGGGCGAATACTTCCGTGACCGTGGTGAAGATGCGCTGATTGTTTATGACGATCTATCAAAACAAGC
GGTGGCTTACCGTCAAATCTCACTACTGCTAAAACGTCCACCAGGTCGTGAAGCCTTCCCTGGTGATGTTTTCTACCTCC
ACTCACGCCTTCTAGAACGTGCTGCACGTGTTAACGAAGAATACGTAGAGCGATTCACTAACGGTGAAGTGAAAGGCAAA
ACAGGTTCTCTAACCGCACTGCCAATCATCGAAACCCAAGCGGGTGACGTATCGGCGTTCGTACCAACCAACGTAATCTC
GATTACCGATGGTCAAATCTTCCTACAAACTCAGCTATTCAACTCAGGCTTACGCCCAGCGGTTGACCCAGGTATTTCGG
TATCTCGTGTAGGTGGTGCAGCGCAAACCAAAGTGATCAAGAAACTGTCGGGTGGTATTCGTACCGCGTTGGCGCAATAC
CGTGAATTGGCCGCATTTGCTCAGTTCTCTTCTGACCTAGATGAAGCGACACGTCGTCAGCTTGACCACGGTGAGAAAGT
AACGGAACTCATGAAGCAGAAACAGTACGCACCAATGACGGTTGCGGAGCAAGCACTGGCGATCTTTGCAGCAGAGAAGG
GTTACCTCACTGATGTGGCACTAAACCAAATCTCTCGTTTTGAAGAAGAGTTGATGGCATTTGGTCGTACAAACGCGCAG
CCGCTACTGGACAAGATCAACCAATCCGGTGATTACAACGACGAGATCGAGAGTGAGCTACACAGCTTGCTGAAAGAGTT
TACTGCGCTGCAATCGTAG

Upstream 100 bases:

>100_bases
TGGTGTGGTGATCACAGCAGGGCAGACCGTGTATGACGGCAGTGTCCTCACCAACCTAAGCCGATTGGCGACCAACCTAC
ATGTGTAACGGGGTATAGAA

Downstream 100 bases:

>100_bases
GACCACTAACAGGAGTCCGTTATGGCAAATACCAAAGAGATTCGCACCAAAATTGCTAGCGTGAATAGCACGCAAAAGAT
TACGAGTGCGATGCAAATGG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MQLNSNEISELIRERIVNFNLESEARNEGTIVSVSDGIITIHGLADVMQGEMLELPNNRFALALNLERHSVGAVVMGPYA
DLSEGMKVKGTGRILEVPVGNGLLGRVVNTLGQPIDGKGAVSFDRMDPVEVIAPGVIDRKSVDQPIQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTAMAIDAIINQKELGVKCIYVAIGQKASTIANVVRKLEEHGALENTIVVVASASEAAALQYLAPY
AGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVNEEYVERFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTQLFNSGLRPAVDPGISVSRVGGAAQTKVIKKLSGGIRTALAQY
RELAAFAQFSSDLDEATRRQLDHGEKVTELMKQKQYAPMTVAEQALAIFAAEKGYLTDVALNQISRFEEELMAFGRTNAQ
PLLDKINQSGDYNDEIESELHSLLKEFTALQS

Sequences:

>Translated_512_residues
MQLNSNEISELIRERIVNFNLESEARNEGTIVSVSDGIITIHGLADVMQGEMLELPNNRFALALNLERHSVGAVVMGPYA
DLSEGMKVKGTGRILEVPVGNGLLGRVVNTLGQPIDGKGAVSFDRMDPVEVIAPGVIDRKSVDQPIQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTAMAIDAIINQKELGVKCIYVAIGQKASTIANVVRKLEEHGALENTIVVVASASEAAALQYLAPY
AGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVNEEYVERFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTQLFNSGLRPAVDPGISVSRVGGAAQTKVIKKLSGGIRTALAQY
RELAAFAQFSSDLDEATRRQLDHGEKVTELMKQKQYAPMTVAEQALAIFAAEKGYLTDVALNQISRFEEELMAFGRTNAQ
PLLDKINQSGDYNDEIESELHSLLKEFTALQS
>Mature_512_residues
MQLNSNEISELIRERIVNFNLESEARNEGTIVSVSDGIITIHGLADVMQGEMLELPNNRFALALNLERHSVGAVVMGPYA
DLSEGMKVKGTGRILEVPVGNGLLGRVVNTLGQPIDGKGAVSFDRMDPVEVIAPGVIDRKSVDQPIQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTAMAIDAIINQKELGVKCIYVAIGQKASTIANVVRKLEEHGALENTIVVVASASEAAALQYLAPY
AGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVNEEYVERFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTQLFNSGLRPAVDPGISVSRVGGAAQTKVIKKLSGGIRTALAQY
RELAAFAQFSSDLDEATRRQLDHGEKVTELMKQKQYAPMTVAEQALAIFAAEKGYLTDVALNQISRFEEELMAFGRTNAQ
PLLDKINQSGDYNDEIESELHSLLKEFTALQS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=511, Percent_Identity=54.4031311154599, Blast_Score=547, Evalue=1e-156,
Organism=Homo sapiens, GI4757810, Length=511, Percent_Identity=54.4031311154599, Blast_Score=547, Evalue=1e-156,
Organism=Homo sapiens, GI19913428, Length=307, Percent_Identity=28.9902280130293, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI32189394, Length=467, Percent_Identity=24.6252676659529, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI19913426, Length=308, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI19913424, Length=263, Percent_Identity=27.3764258555133, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1790172, Length=512, Percent_Identity=80.859375, Blast_Score=860, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=429, Percent_Identity=25.4079254079254, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788251, Length=375, Percent_Identity=24.8, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=514, Percent_Identity=54.863813229572, Blast_Score=558, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71988080, Length=514, Percent_Identity=54.863813229572, Blast_Score=557, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71988074, Length=514, Percent_Identity=51.1673151750973, Blast_Score=509, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17510931, Length=370, Percent_Identity=27.5675675675676, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=308, Percent_Identity=27.9220779220779, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=453, Percent_Identity=23.841059602649, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=272, Percent_Identity=26.1029411764706, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=512, Percent_Identity=52.34375, Blast_Score=539, Evalue=1e-154,
Organism=Saccharomyces cerevisiae, GI6319603, Length=399, Percent_Identity=26.8170426065163, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=432, Percent_Identity=24.537037037037, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24658560, Length=513, Percent_Identity=53.9961013645224, Blast_Score=550, Evalue=1e-157,
Organism=Drosophila melanogaster, GI281361666, Length=307, Percent_Identity=28.9902280130293, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646341, Length=307, Percent_Identity=28.9902280130293, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136796, Length=307, Percent_Identity=28.9902280130293, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24638766, Length=453, Percent_Identity=25.60706401766, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574560, Length=374, Percent_Identity=25.9358288770053, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583992, Length=305, Percent_Identity=27.5409836065574, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24583988, Length=305, Percent_Identity=27.5409836065574, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583986, Length=305, Percent_Identity=27.5409836065574, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583984, Length=305, Percent_Identity=27.5409836065574, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129479, Length=242, Percent_Identity=27.6859504132231, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA2_VIBHB (A7N6Q6)

Other databases:

- EMBL:   CP000790
- RefSeq:   YP_001448226.1
- ProteinModelPortal:   A7N6Q6
- SMR:   A7N6Q6
- STRING:   A7N6Q6
- GeneID:   5556999
- GenomeReviews:   CP000790_GR
- KEGG:   vha:VIBHAR_06106
- NMPDR:   fig|338187.4.peg.3595
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   ALNLERH
- ProtClustDB:   PRK13343
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55713; Mature: 55713

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSNEISELIRERIVNFNLESEARNEGTIVSVSDGIITIHGLADVMQGEMLELPNNRF
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEECHHHHHCCHHHCCCCCCE
ALALNLERHSVGAVVMGPYADLSEGMKVKGTGRILEVPVGNGLLGRVVNTLGQPIDGKGA
EEEEEECCCCCCEEEECCCHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHCCCCCCCCC
VSFDRMDPVEVIAPGVIDRKSVDQPIQTGYKAVDSMVPIGRGQRELIIGDRQTGKTAMAI
EECCCCCCHHHHCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKELGVKCIYVAIGQKASTIANVVRKLEEHGALENTIVVVASASEAAALQYLAPY
HHHHCHHHCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
AGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEEYVERFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTQLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEEHH
NSGLRPAVDPGISVSRVGGAAQTKVIKKLSGGIRTALAQYRELAAFAQFSSDLDEATRRQ
CCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGEKVTELMKQKQYAPMTVAEQALAIFAAEKGYLTDVALNQISRFEEELMAFGRTNAQ
HCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
PLLDKINQSGDYNDEIESELHSLLKEFTALQS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLNSNEISELIRERIVNFNLESEARNEGTIVSVSDGIITIHGLADVMQGEMLELPNNRF
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEECHHHHHCCHHHCCCCCCE
ALALNLERHSVGAVVMGPYADLSEGMKVKGTGRILEVPVGNGLLGRVVNTLGQPIDGKGA
EEEEEECCCCCCEEEECCCHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHCCCCCCCCC
VSFDRMDPVEVIAPGVIDRKSVDQPIQTGYKAVDSMVPIGRGQRELIIGDRQTGKTAMAI
EECCCCCCHHHHCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKELGVKCIYVAIGQKASTIANVVRKLEEHGALENTIVVVASASEAAALQYLAPY
HHHHCHHHCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
AGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEEYVERFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTQLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEEHH
NSGLRPAVDPGISVSRVGGAAQTKVIKKLSGGIRTALAQYRELAAFAQFSSDLDEATRRQ
CCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGEKVTELMKQKQYAPMTVAEQALAIFAAEKGYLTDVALNQISRFEEELMAFGRTNAQ
HCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
PLLDKINQSGDYNDEIESELHSLLKEFTALQS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA